Lineage for Family a.60.2.5: Hef domain-like

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1998615Fold a.60: SAM domain-like [47768] (16 superfamilies)
    4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins
  4. 1998807Superfamily a.60.2: RuvA domain 2-like [47781] (7 families) (S)
    duplication: contains two helix-hairpin-helix (HhH) motifs
  5. 1998863Family a.60.2.5: Hef domain-like [140629] (4 protein domains)
    helicase/nuclease domain; forms homo and heterodimers; probably includes the Excinuclease UvrC C-terminal domain ((81795), that contains a single NMR structure of a monomeric truncated domain, 1kft)

Protein Domains:

  1. 1998864ATP-dependent RNA helicase PF2015 [140632] (1 species)
  2. 1998868DNA excision repair protein ERCC-1 [140630] (1 species)
  3. 1998873DNA repair endonuclease XPF [140634] (2 species)
    1. 1998874Species Aeropyrum pernix [TaxId:56636] [140635] (2 PDB entries)
      Uniprot Q9YC15 160-229
    2. 1998881Species Human (Homo sapiens) [TaxId:9606] [140636] (4 PDB entries)
      Uniprot Q92889 823-905! Uniprot Q92889 837-898
  4. 1998887automated matches [254584] (1 species)
    not a true protein

More info for Family a.60.2.5: Hef domain-like

Timeline for Family a.60.2.5: Hef domain-like: