SCOPe 2.08: Domain d1sc6b1: 1sc6 B:108-295

Lineage for d1sc6b1 (1sc6 B:108-295)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.4: Formate/glycerate dehydrogenases, NAD-domain [51830] (10 proteins)
   this domain interrupts the other domain which defines family

6. Protein Phosphoglycerate dehydrogenase [51839] (2 species)
   has additional C-terminal domain of the ferredoxin fold

7. Species Escherichia coli [TaxId:562] [51840] (7 PDB entries)

8. Domain d1sc6b1: 1sc6 B:108-295 [118935]
   Other proteins in same PDB: d1sc6a2, d1sc6a3, d1sc6b2, d1sc6b3, d1sc6c2, d1sc6c3, d1sc6d2, d1sc6d3
   automatically matched to d1psda1
   complexed with nad

Details for d1sc6b1

PDB Entry: 1sc6, 2.09 Å

PDB Description: crystal structure of w139g d-3-phosphoglycerate dehydrogenase complexed with nad+

PDB Compounds: (B:) D-3-phosphoglycerate dehydrogenase

SCOPe Domain Sequences for d1sc6b1:

Sequence, based on SEQRES records:

>d1sc6b1 c.2.1.4 (B:108-295) Phosphoglycerate dehydrogenase {Escherichia coli [TaxId: 562]}
ntrsvaelvigelllllrgvpeanakahrgvgnklaagsfeargkklgiigyghigtqlg
ilaeslgmyvyfydienklplgnatqvqhlsdllnmsdvvslhvpenpstknmmgakeis
lmkpgsllinasrgtvvdipaladalaskhlagaaidvfptepatnsdpftsplaefdnv
lltphigg

Sequence, based on observed residues (ATOM records):

>d1sc6b1 c.2.1.4 (B:108-295) Phosphoglycerate dehydrogenase {Escherichia coli [TaxId: 562]}
ntrsvaelvigelllllrgvpeanakahrgvgnsfeargkklgiigyghigtqlgilaes
lgmyvyfydienklplgnatqvqhlsdllnmsdvvslhvpenpstknmmgakeislmkpg
sllinasrgtvvdipaladalaskhlagaaidsplaefdnvlltphigg

Timeline for d1sc6b1:

• d1sc6b1 first appeared in SCOP 1.73
  
• d1sc6b1 appears in SCOPe 2.07