Lineage for Protein: Apoptosis regulator Bcl-xL

  1. Root: SCOPe 2.07
  2. 2626587Class f: Membrane and cell surface proteins and peptides [56835] (60 folds)
  3. 2626588Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
    multi-helical domains of various folds which is thought to unfold in the membrane
  4. 2626682Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families) (S)
    PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain
  5. 2626683Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
    Pfam PF00452
  6. 2626689Protein Apoptosis regulator Bcl-xL [56856] (3 species)

Species:

  1. 2626690Human (Homo sapiens) [TaxId:9606] [56857] (46 PDB entries)
    1. Domain for 1bxl:
    2. Domain for 1g5j:
    3. Domain for 1lxl:
    4. Domain for 1maz:
    5. Domain for 1r2d:
    6. Domain for 1r2e:
    7. Domain for 1r2g:
    8. Domain for 1r2h:
    9. Domain for 1r2i:
    10. Domain for 1ysg:
    11. Domain for 1ysi:
    12. Domain for 1ysn:
    13. Domain for 2b48:
    14. Domain for 2lpc:
    15. Domain for 2me8:
    16. Domain for 2me9:
    17. Domain for 2o1y:
    18. Domain for 2o2m:
    19. Domain for 2o2n:
    20. Domains for 2p1l:
      1. 2626765Domain d2p1la_: 2p1l A: [166945]
        automated match to d1g5ja_
      2. 2626766Domain d2p1lc_: 2p1l C: [166946]
        automated match to d1g5ja_
      3. 2626767Domain d2p1le_: 2p1l E: [166947]
        automated match to d1g5ja_
      4. 2626768Domain d2p1lg_: 2p1l G: [166948]
        automated match to d1g5ja_
    21. Domain for 2pon:
    22. Domains for 2yxj:
      1. 2626754Domain d2yxja_: 2yxj A: [170913]
        automated match to d1g5ja_
        complexed with cl, gol, n3c
      2. 2626755Domain d2yxjb_: 2yxj B: [170914]
        automated match to d1g5ja_
        complexed with cl, gol, n3c
    23. Domain for 3cva:
    24. Domains for 3io8:
      1. 2626758Domain d3io8a1: 3io8 A:1-197 [178474]
        Other proteins in same PDB: d3io8a2, d3io8c2
        automated match to d1g5ja_
        complexed with zn
      2. 2626759Domain d3io8c1: 3io8 C:1-197 [178475]
        Other proteins in same PDB: d3io8a2, d3io8c2
        automated match to d1g5ja_
        complexed with zn
    25. Domains for 3pl7:
      1. 2626756Domain d3pl7a_: 3pl7 A: [183827]
        automated match to d1g5ja_
      2. 2626757Domain d3pl7b_: 3pl7 B: [183828]
        automated match to d1g5ja_
    26. Domains for 3qkd:
      1. 2626697Domain d3qkda_: 3qkd A: [184464]
        automated match to d1g5ja_
        complexed with cl, gol, hi0
      2. 2626698Domain d3qkdb_: 3qkd B: [184465]
        automated match to d1g5ja_
        complexed with cl, gol, hi0
    27. Domain for 3sp7:
    28. Domain for 3spf:
    29. Domains for 3wiz:
      1. 2626763Domain d3wiza_: 3wiz A: [233972]
        automated match to d1g5ja_
        complexed with lc6, po4
      2. 2626764Domain d3wizb_: 3wiz B: [233973]
        automated match to d1g5ja_
        complexed with lc6, po4
    30. Domain for 4ehr:
    31. Domain for 4ppi:
    32. Domains for 4qvx:
      1. 2626748Domain d4qvxa_: 4qvx A: [275212]
        automated match to d2m03a_
        complexed with 3cq
      2. 2626749Domain d4qvxb_: 4qvx B: [275211]
        automated match to d2m03a_
        complexed with 3cq
    33. Domains for 4tuh:
      1. 2626705Domain d4tuha1: 4tuh A:1-196 [260442]
        Other proteins in same PDB: d4tuha2, d4tuhb2, d4tuhc2, d4tuhf2, d4tuhg2, d4tuhh2
        automated match to d1ysga_
        complexed with 38h, act, edo
      2. 2626706Domain d4tuhb1: 4tuh B:1-196 [263918]
        Other proteins in same PDB: d4tuha2, d4tuhb2, d4tuhc2, d4tuhf2, d4tuhg2, d4tuhh2
        automated match to d2o1ya_
        complexed with 38h, act, edo
      3. 2626707Domain d4tuhc1: 4tuh C:1-197 [263919]
        Other proteins in same PDB: d4tuha2, d4tuhb2, d4tuhc2, d4tuhf2, d4tuhg2, d4tuhh2
        automated match to d2o1ya_
        complexed with 38h, act, edo
      4. 2626708Domain d4tuhd_: 4tuh D: [263920]
        Other proteins in same PDB: d4tuha2, d4tuhb2, d4tuhc2, d4tuhf2, d4tuhg2, d4tuhh2
        automated match to d2o1ya_
        complexed with 38h, act, edo
      5. 2626709Domain d4tuhe_: 4tuh E: [263921]
        Other proteins in same PDB: d4tuha2, d4tuhb2, d4tuhc2, d4tuhf2, d4tuhg2, d4tuhh2
        automated match to d2o1ya_
        complexed with 38h, act, edo
      6. 2626710Domain d4tuhf1: 4tuh F:1-198 [263922]
        Other proteins in same PDB: d4tuha2, d4tuhb2, d4tuhc2, d4tuhf2, d4tuhg2, d4tuhh2
        automated match to d2o1ya_
        complexed with 38h, act, edo
      7. 2626711Domain d4tuhg1: 4tuh G:1-196 [263923]
        Other proteins in same PDB: d4tuha2, d4tuhb2, d4tuhc2, d4tuhf2, d4tuhg2, d4tuhh2
        automated match to d2o1ya_
        complexed with 38h, act, edo
      8. 2626712Domain d4tuhh1: 4tuh H:1-197 [263924]
        Other proteins in same PDB: d4tuha2, d4tuhb2, d4tuhc2, d4tuhf2, d4tuhg2, d4tuhh2
        automated match to d2o1ya_
        complexed with 38h, act, edo
    34. Domains for 4z9v:
      1. 2626746Domain d4z9va1: 4z9v A:1-208 [312299]
        Other proteins in same PDB: d4z9va2
        automated match to d1zy3a1
        complexed with bct, na
      2. 2626747Domain d4z9vb_: 4z9v B: [312403]
        Other proteins in same PDB: d4z9va2
        automated match to d1zy3a1
        complexed with bct, na
    35. Domains for 5b1z:
      1. 2626751Domain d5b1za_: 5b1z A: [327550]
        automated match to d4z9vb_
      2. 2626752Domain d5b1zb_: 5b1z B: [327567]
        automated match to d4z9vb_
    36. Domain for 6bf2:
    37. Domains for 6uvc:
      1. 2626699Domain d6uvca_: 6uvc A: [403902]
        Other proteins in same PDB: d6uvcb2
        automated match to d4z9vb_
        complexed with edo, so4, xoy
      2. 2626700Domain d6uvcb1: 6uvc B:1-197 [403958]
        Other proteins in same PDB: d6uvcb2
        automated match to d4z9vb_
        complexed with edo, so4, xoy
    38. Domains for 6uvd:
      1. 2626718Domain d6uvda1: 6uvd A:1-197 [403877]
        Other proteins in same PDB: d6uvda2
        automated match to d4z9vb_
        complexed with edo, so4, xou
      2. 2626719Domain d6uvdb_: 6uvd B: [403901]
        Other proteins in same PDB: d6uvda2
        automated match to d4z9vb_
        complexed with edo, so4, xou
    39. Domains for 6uve:
      1. 2626760Domain d6uvea1: 6uve A:1-196 [403868]
        Other proteins in same PDB: d6uvea2
        automated match to d4z9vb_
        complexed with edo, qhv
      2. 2626761Domain d6uveb_: 6uve B: [403895]
        Other proteins in same PDB: d6uvea2
        automated match to d4z9vb_
        complexed with edo, qhv
      3. 2626762Domain d6uvec_: 6uve C: [403880]
        Other proteins in same PDB: d6uvea2
        automated match to d4z9vb_
        complexed with edo, qhv
    40. Domains for 6uvf:
      1. 2626732Domain d6uvfa1: 6uvf A:1-196 [403963]
        Other proteins in same PDB: d6uvfa2, d6uvfb2, d6uvfc2, d6uvfd2, d6uvfh2, d6uvfj2, d6uvfk2, d6uvfl2
        automated match to d4z9vb_
        complexed with edo, qhs, so4
      2. 2626733Domain d6uvfb1: 6uvf B:1-196 [403978]
        Other proteins in same PDB: d6uvfa2, d6uvfb2, d6uvfc2, d6uvfd2, d6uvfh2, d6uvfj2, d6uvfk2, d6uvfl2
        automated match to d4z9vb_
        complexed with edo, qhs, so4
      3. 2626734Domain d6uvfc1: 6uvf C:1-196 [403990]
        Other proteins in same PDB: d6uvfa2, d6uvfb2, d6uvfc2, d6uvfd2, d6uvfh2, d6uvfj2, d6uvfk2, d6uvfl2
        automated match to d4z9vb_
        complexed with edo, qhs, so4
      4. 2626735Domain d6uvfd1: 6uvf D:1-196 [403907]
        Other proteins in same PDB: d6uvfa2, d6uvfb2, d6uvfc2, d6uvfd2, d6uvfh2, d6uvfj2, d6uvfk2, d6uvfl2
        automated match to d4z9vb_
        complexed with edo, qhs, so4
      5. 2626736Domain d6uvfe_: 6uvf E: [403965]
        Other proteins in same PDB: d6uvfa2, d6uvfb2, d6uvfc2, d6uvfd2, d6uvfh2, d6uvfj2, d6uvfk2, d6uvfl2
        automated match to d4z9vb_
        complexed with edo, qhs, so4
      6. 2626737Domain d6uvff_: 6uvf F: [403989]
        Other proteins in same PDB: d6uvfa2, d6uvfb2, d6uvfc2, d6uvfd2, d6uvfh2, d6uvfj2, d6uvfk2, d6uvfl2
        automated match to d4z9vb_
        complexed with edo, qhs, so4
      7. 2626738Domain d6uvfg_: 6uvf G: [403946]
        Other proteins in same PDB: d6uvfa2, d6uvfb2, d6uvfc2, d6uvfd2, d6uvfh2, d6uvfj2, d6uvfk2, d6uvfl2
        automated match to d4z9vb_
        complexed with edo, qhs, so4
      8. 2626739Domain d6uvfh1: 6uvf H:1-196 [403953]
        Other proteins in same PDB: d6uvfa2, d6uvfb2, d6uvfc2, d6uvfd2, d6uvfh2, d6uvfj2, d6uvfk2, d6uvfl2
        automated match to d4z9vb_
        complexed with edo, qhs, so4
      9. 2626740Domain d6uvfi_: 6uvf I: [404093]
        Other proteins in same PDB: d6uvfa2, d6uvfb2, d6uvfc2, d6uvfd2, d6uvfh2, d6uvfj2, d6uvfk2, d6uvfl2
        automated match to d4z9vb_
        complexed with edo, qhs, so4
      10. 2626741Domain d6uvfj1: 6uvf J:1-195 [404043]
        Other proteins in same PDB: d6uvfa2, d6uvfb2, d6uvfc2, d6uvfd2, d6uvfh2, d6uvfj2, d6uvfk2, d6uvfl2
        automated match to d4z9vb_
        complexed with edo, qhs, so4
      11. 2626742Domain d6uvfk1: 6uvf K:1-202 [403985]
        Other proteins in same PDB: d6uvfa2, d6uvfb2, d6uvfc2, d6uvfd2, d6uvfh2, d6uvfj2, d6uvfk2, d6uvfl2
        automated match to d4z9vb_
        complexed with edo, qhs, so4
      12. 2626743Domain d6uvfl1: 6uvf L:1-195 [404099]
        Other proteins in same PDB: d6uvfa2, d6uvfb2, d6uvfc2, d6uvfd2, d6uvfh2, d6uvfj2, d6uvfk2, d6uvfl2
        automated match to d4z9vb_
        complexed with edo, qhs, so4
    41. Domains for 6uvg:
      1. 2626720Domain d6uvga1: 6uvg A:1-197 [403950]
        Other proteins in same PDB: d6uvga2, d6uvgb2, d6uvgd2, d6uvgg2, d6uvgh2, d6uvgk2, d6uvgl2
        automated match to d4z9vb_
        complexed with edo, qhp, so4
      2. 2626721Domain d6uvgb1: 6uvg B:1-196 [403928]
        Other proteins in same PDB: d6uvga2, d6uvgb2, d6uvgd2, d6uvgg2, d6uvgh2, d6uvgk2, d6uvgl2
        automated match to d4z9vb_
        complexed with edo, qhp, so4
      3. 2626722Domain d6uvgc_: 6uvg C: [403879]
        Other proteins in same PDB: d6uvga2, d6uvgb2, d6uvgd2, d6uvgg2, d6uvgh2, d6uvgk2, d6uvgl2
        automated match to d4z9vb_
        complexed with edo, qhp, so4
      4. 2626723Domain d6uvgd1: 6uvg D:1-195 [403865]
        Other proteins in same PDB: d6uvga2, d6uvgb2, d6uvgd2, d6uvgg2, d6uvgh2, d6uvgk2, d6uvgl2
        automated match to d4z9vb_
        complexed with edo, qhp, so4
      5. 2626724Domain d6uvge_: 6uvg E: [403872]
        Other proteins in same PDB: d6uvga2, d6uvgb2, d6uvgd2, d6uvgg2, d6uvgh2, d6uvgk2, d6uvgl2
        automated match to d4z9vb_
        complexed with edo, qhp, so4
      6. 2626725Domain d6uvgf_: 6uvg F: [404040]
        Other proteins in same PDB: d6uvga2, d6uvgb2, d6uvgd2, d6uvgg2, d6uvgh2, d6uvgk2, d6uvgl2
        automated match to d4z9vb_
        complexed with edo, qhp, so4
      7. 2626726Domain d6uvgg1: 6uvg G:1-196 [403885]
        Other proteins in same PDB: d6uvga2, d6uvgb2, d6uvgd2, d6uvgg2, d6uvgh2, d6uvgk2, d6uvgl2
        automated match to d4z9vb_
        complexed with edo, qhp, so4
      8. 2626727Domain d6uvgh1: 6uvg H:1-197 [403873]
        Other proteins in same PDB: d6uvga2, d6uvgb2, d6uvgd2, d6uvgg2, d6uvgh2, d6uvgk2, d6uvgl2
        automated match to d4z9vb_
        complexed with edo, qhp, so4
      9. 2626728Domain d6uvgi_: 6uvg I: [403882]
        Other proteins in same PDB: d6uvga2, d6uvgb2, d6uvgd2, d6uvgg2, d6uvgh2, d6uvgk2, d6uvgl2
        automated match to d4z9vb_
        complexed with edo, qhp, so4
      10. 2626729Domain d6uvgj_: 6uvg J: [403874]
        Other proteins in same PDB: d6uvga2, d6uvgb2, d6uvgd2, d6uvgg2, d6uvgh2, d6uvgk2, d6uvgl2
        automated match to d4z9vb_
        complexed with edo, qhp, so4
      11. 2626730Domain d6uvgk1: 6uvg K:1-197 [403930]
        Other proteins in same PDB: d6uvga2, d6uvgb2, d6uvgd2, d6uvgg2, d6uvgh2, d6uvgk2, d6uvgl2
        automated match to d4z9vb_
        complexed with edo, qhp, so4
      12. 2626731Domain d6uvgl1: 6uvg L:1-195 [403982]
        Other proteins in same PDB: d6uvga2, d6uvgb2, d6uvgd2, d6uvgg2, d6uvgh2, d6uvgk2, d6uvgl2
        automated match to d4z9vb_
        complexed with edo, qhp, so4
    42. Domains for 6uvh:
      1. 2626713Domain d6uvha1: 6uvh A:1-196 [403892]
        Other proteins in same PDB: d6uvha2
        automated match to d4z9vb_
        complexed with edo, qhj, so4
      2. 2626714Domain d6uvhb_: 6uvh B: [403889]
        Other proteins in same PDB: d6uvha2
        automated match to d4z9vb_
        complexed with edo, qhj, so4
      3. 2626715Domain d6uvhc_: 6uvh C: [403910]
        Other proteins in same PDB: d6uvha2
        automated match to d4z9vb_
        complexed with edo, qhj, so4
      4. 2626716Domain d6uvhd_: 6uvh D: [403883]
        Other proteins in same PDB: d6uvha2
        automated match to d4z9vb_
        complexed with edo, qhj, so4
    43. Domains for 6vwc:
      1. 2626694Domain d6vwca_: 6vwc A: [392838]
        automated match to d4z9vb_
        complexed with rq7
      2. 2626695Domain d6vwcb_: 6vwc B: [392839]
        automated match to d4z9vb_
        complexed with rq7
    44. Domains for 7jgv:
      1. 2626702Domain d7jgva_: 7jgv A: [398964]
        automated match to d4z9vb_
        complexed with v9s
      2. 2626703Domain d7jgvb_: 7jgv B: [398967]
        automated match to d4z9vb_
        complexed with v9s
    45. Domain for 7jgw:
    46. Domains for 7lh7:
      1. 2626692Domain d7lh7a_: 7lh7 A: [405519]
        automated match to d4z9vb_
        complexed with xzm
      2. 2626693Domain d7lh7b_: 7lh7 B: [405553]
        automated match to d4z9vb_
        complexed with xzm
  2. 2626787Mouse (Mus musculus) [TaxId:10090] [103423] (9 PDB entries)
    1. Domain for 1pq0:
    2. Domain for 1pq1:
    3. Domain for 3ihc:
    4. Domain for 3ihd:
    5. Domains for 3ihf:
      1. 2626793Domain d3ihfa_: 3ihf A: [211686]
        automated match to d1r2da_
        mutant
      2. 2626794Domain d3ihfb_: 3ihf B: [211687]
        automated match to d1r2da_
        mutant
      3. 2626795Domain d3ihfc_: 3ihf C: [211688]
        automated match to d1r2da_
        mutant
      4. 2626796Domain d3ihfd_: 3ihf D: [211689]
        automated match to d1r2da_
        mutant
    6. Domain for 3iig:
    7. Domain for 3iih:
    8. Domains for 3ilb:
      1. 2626798Domain d3ilba_: 3ilb A: [211817]
        automated match to d1r2da_
        mutant
      2. 2626799Domain d3ilbn_: 3ilb N: [211818]
        automated match to d1r2da_
        mutant
    9. Domain for 3ilc:
  3. 2626801Norway rat (Rattus norvegicus) [TaxId:10116] [56858] (1 PDB entry)

More info for Protein Apoptosis regulator Bcl-xL from f.1.4.1: Bcl-2 inhibitors of programmed cell death

Timeline for Protein Apoptosis regulator Bcl-xL from f.1.4.1: Bcl-2 inhibitors of programmed cell death: