PDB entry 1r2i

View 1r2i on RCSB PDB site
Description: Human Bcl-XL containing a Phe to Leu mutation at position 146
Class: apoptosis
Keywords: Apoptosis, monomeric, alpha-helical, mutation
Deposited on 2003-09-26, released 2004-02-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: apoptosis regulator bcl-x
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL-XL
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07817 (0-End)
      • engineered (145)
    Domains in SCOPe 2.07: d1r2ia_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1r2iA (A:)
msqsnrelvvdflsyklsqkgyswsqfsdveenrteapegtesemetpsaingnpswhla
dspavngatghsssldarevipmaavkqalreagdefelryrrafsdltsqlhitpgtay
qsfeqvvnelfrdgvnwgrivaffslggalcvesvdkemqvlvsriaawmatylndhlep
wiqenggwdtfvelygnnaaaesrkgqerfnehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1r2iA (A:)
msqsnrelvvdflsyklsqkgyswsqfpmaavkqalreagdefelryrrafsdltsqlhi
tpgtayqsfeqvvnelfrdgvnwgrivaffslggalcvesvdkemqvlvsriaawmatyl
ndhlepwiqenggwdtfvelygn