SCOPe 2.08: Domain d1d6eb1: 1d6e B:93-190

Lineage for d1d6eb1 (1d6e B:93-190)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Class II MHC beta chain, C-terminal domain [88625] (6 species)

7. Species Human (Homo sapiens), HLA-DR group [TaxId:9606] [88628] (43 PDB entries)
   Uniprot P04229 30-219
   probably orthologous to the mouse I-E group

8. Domain d1d6eb1: 1d6e B:93-190 [21622]
   Other proteins in same PDB: d1d6ea1, d1d6ea2, d1d6eb2, d1d6ec1, d1d6ec2

Details for d1d6eb1

PDB Entry: 1d6e, 2.45 Å

PDB Description: crystal structure of hla-dr4 complex with peptidomimetic and seb

PDB Compounds: (B:) hla class II histocompatibility antigen

SCOPe Domain Sequences for d1d6eb1:

Sequence, based on SEQRES records:

>d1d6eb1 b.1.1.2 (B:93-190) Class II MHC beta chain, C-terminal domain {Human (Homo sapiens), HLA-DR group [TaxId: 9606]}
rrvypevtvypaktqplqhhnllvcsvngfypgsievrwfrngqeektgvvstgliqngd
wtfqtlvmletvprsgevytcqvehpsltspltvewra

Sequence, based on observed residues (ATOM records):

>d1d6eb1 b.1.1.2 (B:93-190) Class II MHC beta chain, C-terminal domain {Human (Homo sapiens), HLA-DR group [TaxId: 9606]}
rrvypevtvypallvcsvngfypgsievrwfrngqeektgvvstgliqngdwtfqtlvml
etvprsgevytcqvehpsltspltvewra

Timeline for d1d6eb1:

• d1d6eb1 first appeared (with stable ids) in SCOP 1.55
  
• d1d6eb1 appears in SCOPe 2.07