Lineage for Class b: All beta proteins

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)

Folds:

  1. 2344608b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  2. 2363595b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (9 superfamilies)
    sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold
  3. 2364769b.3: Prealbumin-like [49451] (8 superfamilies)
    sandwich; 7 strands in 2 sheets, greek-key
    variations: some members have additional 1-2 strands to common fold
  4. 2366362b.4: HSP40/DnaJ peptide-binding domain [49492] (1 superfamily)
    sandwich; 6 strands in 2 sheets
  5. 2366391b.5: alpha-Amylase inhibitor tendamistat [49497] (1 superfamily)
    sandwich; 6 strands in 2 sheets
  6. 2366402b.6: Cupredoxin-like [49502] (2 superfamilies)
    sandwich; 7 strands in 2 sheets, greek-key
    variations: some members have additional 1-2 strands
  7. 2368400b.7: C2 domain-like [49561] (5 superfamilies)
    sandwich; 8 strands in 2 sheets; greek-key
  8. 2368843b.8: TRAF domain-like [49598] (1 superfamily)
    sandwich; 8 strands in 2 sheets; greek-key
  9. 2368964b.9: Neurophysin II [49605] (1 superfamily)
    sandwich; 8 strands in 2 sheets; meander
  10. 2368998b.11: gamma-Crystallin-like [49694] (1 superfamily)
    sandwich; 8 strands in 2 sheets; greek-key
    duplication: has internal pseudo twofold symmetry
  11. 2369212b.12: Lipase/lipooxygenase domain (PLAT/LH2 domain) [49722] (1 superfamily)
    sandwich; 8 strands in 2 sheets; complex topology
    duplication: has weak internal pseudo twofold symmetry
  12. 2369319b.14: Calpain large subunit, middle domain (domain III) [49757] (1 superfamily)
    sandwich; 8 strands in 2 sheets; jelly-roll
  13. 2369336b.15: HSP20-like chaperones [49763] (1 superfamily)
    sandwich; 8 strands in 2 sheets; greek-key
  14. 2369490b.16: Ecotin, trypsin inhibitor [49771] (1 superfamily)
    sandwich; 8 strands in 2 sheets; complex topology with the crossing loops
  15. 2369531b.17: PEBP-like [49776] (1 superfamily)
    sandwich; 8 strands in 2 sheets; greek-key: partial topological similarity to immunoglobulin-like folds
  16. 2369590b.18: Galactose-binding domain-like [49784] (1 superfamily)
    sandwich; 9 strands in 2 sheets; jelly-roll
  17. 2370814b.19: Viral protein domain [49817] (1 superfamily)
    sandwich; 9 strands in 2 sheets; jelly-roll; form trimers
  18. 2371813b.20: ENV polyprotein, receptor-binding domain [49829] (1 superfamily)
    sandwich; 9 strands in 2 sheets; greek-key; contains a few helices in loop regions
  19. 2371823b.21: Virus attachment protein globular domain [49834] (1 superfamily)
    sandwich, 10 strands in 2 sheets; greek-key
  20. 2372079b.22: TNF-like [49841] (1 superfamily)
    sandwich, 10 strands in 2 sheets; jelly-roll
  21. 2372519b.23: CUB-like [49853] (3 superfamilies)
    sandwich, 10 strands in 2 sheets; jelly-roll
  22. 2372607b.24: Hyaluronate lyase-like, C-terminal domain [49862] (2 superfamilies)
    sandwich, 10 strands in 2 sheets; "folded meander"
  23. 2372691b.25: Osmotin, thaumatin-like protein [49869] (1 superfamily)
    sandwich; 11 strands in 2 sheets
  24. 2372848b.26: SMAD/FHA domain [49878] (1 superfamily)
    sandwich; 11 strands in 2 sheets; greek-key
  25. 2373010b.27: Soluble secreted chemokine inhibitor, VCCI [49888] (1 superfamily)
    sandwich; 11 strands in 2 sheets; greek-key
  26. 2373024b.28: Baculovirus p35 protein [49893] (1 superfamily)
    sandwich; 14 strands in 2 sheets; greek-key
  27. 2373039b.29: Concanavalin A-like lectins/glucanases [49898] (1 superfamily)
    sandwich; 12-14 strands in 2 sheets; complex topology
  28. 2375752b.30: Supersandwich [49993] (3 superfamilies)
    sandwich; 18 strands in 2 sheets
  29. 2376479b.31: EV matrix protein [50011] (1 superfamily)
    consists of two beta-sandwich domains of similar topologies
  30. 2376507b.32: gp9 [50016] (1 superfamily)
    consists of two different beta-sandwich domains unrelated to other beta-sandwich folds
  31. 2376534b.33: ISP domain [50021] (1 superfamily)
    consists of two all-beta subdomains: conserved small domain has a rubredoxin-like fold; larger domain consists of 6 beta-stands packed in either sandwich of two 3-stranded sheets or closed barrel (n=6; S=8)
  32. 2376890b.34: SH3-like barrel [50036] (21 superfamilies)
    barrel, partly opened; n*=4, S*=8; meander
    the last strand is interrupted by a turn of 3-10 helix
  33. 2379160b.35: GroES-like [50128] (2 superfamilies)
    contains barrel, partly opened; n*=4, S*=8; meander
  34. 2379659b.36: PDZ domain-like [50155] (1 superfamily)
    contains barrel, partly opened; n*=4, S*=8; meander; capped by alpha-helix
  35. 2380416b.37: N-terminal domains of the minor coat protein g3p [50175] (1 superfamily)
    core: barrel, in some members open; n*=4, S*=8; meander
  36. 2380450b.38: Sm-like fold [50181] (5 superfamilies)
    core: barrel, open; n*=4, S*=8; meander; SH3-like topology
  37. 2381352b.39: Ribosomal protein L14 [50192] (1 superfamily)
    barrel, closed; n=5, S=8, meander
  38. 2381452b.40: OB-fold [50198] (17 superfamilies)
    barrel, closed or partly opened n=5, S=10 or S=8; greek-key
  39. 2384684b.41: PRC-barrel domain [50345] (1 superfamily)
    core: barrel, partly opened; n*=5, S*=8; meander
  40. 2384842b.42: beta-Trefoil [50352] (8 superfamilies)
    barrel, closed; n=6, S=12; and a hairpin triplet; meander
    duplication: has internal pseudo threefold symmetry
  41. 2385975b.43: Reductase/isomerase/elongation factor common domain [50412] (4 superfamilies)
    barrel, closed; n=6, S=10; greek-key
  42. 2386873b.44: Elongation factor/aminomethyltransferase common domain [50464] (2 superfamilies)
    barrel, closed; n=6, S=10; greek-key
  43. 2387119b.45: Split barrel-like [50474] (3 superfamilies)
    barrel; n=6, S=10; greek-key
  44. 2387475b.46: FMT C-terminal domain-like [50485] (1 superfamily)
    barrel, open; n*=6, S*=10; greek-key
  45. 2387558b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  46. 2390551b.48: mu transposase, C-terminal domain [50609] (1 superfamily)
    barrel; n=6, S=8, greek-key
  47. 2390559b.49: Domain of alpha and beta subunits of F1 ATP synthase-like [50614] (4 superfamilies)
    barrel, closed; n=6, S=8; greek-key
    Many cradle-loop superfamilies may be homologous, according to PubMed 18457946
  48. 2391025b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  49. 2393881b.51: ValRS/IleRS/LeuRS editing domain [50676] (1 superfamily)
    core: barrel, closed; n=6, S=8; topology is similar to that of the acid proteases barrel
  50. 2393919b.52: Double psi beta-barrel [50684] (2 superfamilies)
    barrel, closed; n=6, S=10; complex topology with crossover (psi) loops
  51. 2394256b.53: Ribosomal protein L25-like [50714] (1 superfamily)
    barrel, closed; n=6, S=10; complex topology
  52. 2394348b.54: Core binding factor beta, CBF [50722] (1 superfamily)
    barrel, closed; n=6, S=10; meander; capped at both ends by alpha-helices
  53. 2394380b.55: PH domain-like barrel [50728] (3 superfamilies)
    barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix
  54. 2395139b.56: Transcription factor IIA (TFIIA), beta-barrel domain [50783] (1 superfamily)
    barrel, closed; n=6, S=12; mixed beta-sheet
  55. 2395155b.57: Herpes virus serine proteinase, assemblin [50788] (1 superfamily)
    core: barrel, closed; n=7, S=8; complex topology
  56. 2395224b.58: PK beta-barrel domain-like [50799] (1 superfamily)
    barrel, closed; n=7, S=10; complex topology
  57. 2395383b.59: XRCC4, N-terminal domain [50808] (1 superfamily)
    barrel, closed; n=7, S=10; order: 1234765; strands 1 and 5 are parallel to each other
  58. 2395396b.60: Lipocalins [50813] (1 superfamily)
    barrel, closed or opened; n=8, S=12; meander
  59. 2396657b.61: Streptavidin-like [50875] (8 superfamilies)
    barrel, closed; n=8, S=10; meander
  60. 2397365b.62: Cyclophilin-like [50890] (1 superfamily)
    barrel, closed; n=8, S=10; complex topology
  61. 2397791b.63: Oncogene products [50903] (1 superfamily)
    barrel, closed; n=8, S=10; one overside connection
  62. 2397805b.64: Mannose 6-phosphate receptor domain [50910] (1 superfamily)
    barrel, partly open; n*=8, S*=10; one psi loop
  63. 2397876b.65: triple barrel [50915] (1 superfamily)
    dimer of two non-identical subunits; forms two similar barrels, n=8, S=10 each, that are fused together with the formation of third barrel, n=6, S=8
  64. 2397935b.66: 4-bladed beta-propeller [50922] (1 superfamily)
    consists of four 4-stranded beta-sheet motifs; meander
  65. 2397987b.67: 5-bladed beta-propeller [50933] (3 superfamilies)
    consists of five 4-stranded beta-sheet motifs; meander
  66. 2398193b.68: 6-bladed beta-propeller [50938] (11 superfamilies)
    consists of six 4-stranded beta-sheet motifs; meander
  67. 2399102b.69: 7-bladed beta-propeller [50964] (15 superfamilies)
    consists of seven 4-stranded beta-sheet motifs; meander
  68. 2399926b.70: 8-bladed beta-propeller [50997] (3 superfamilies)
    consists of eight 4-stranded beta-sheet motifs; meander
    also found in some members of the WD40-repeat superfamily
  69. 2400339b.71: Glycosyl hydrolase domain [51010] (1 superfamily)
    folded sheet; greek-key
  70. 2401160b.72: WW domain-like [51044] (3 superfamilies)
    core: 3-stranded meander beta-sheet
  71. 2401360b.73: Head domain of nucleotide exchange factor GrpE [51063] (1 superfamily)
    small mixed beta-sheet, 4 "generalized" strands
  72. 2401367b.74: Carbonic anhydrase [51068] (1 superfamily)
    single sheet; 10 strands
  73. 2402431b.75: Bacteriochlorophyll A protein [51080] (1 superfamily)
    single sheet; 16 strands; meander
  74. 2402454b.76: open-sided beta-meander [51086] (2 superfamilies)
    single sheet formed by beta-hairpin repeats; exposed on both sides in the middle
  75. 2402521b.77: beta-Prism I [51091] (3 superfamilies)
    consists of 3 4-stranded sheets; strands are parallel to the 3-fold axis
    duplication: has internal pseudo threefold symmetry
  76. 2402758b.78: beta-Prism II [51109] (1 superfamily)
    consists of 3 4-stranded sheets; strands are perpendicular to the 3-fold axis
    duplication: consists of two domains of this fold
  77. 2402886b.80: Single-stranded right-handed beta-helix [51125] (8 superfamilies)
    superhelix turns are made of parallel beta-strands and (short) turns
  78. 2403213b.81: Single-stranded left-handed beta-helix [51160] (4 superfamilies)
    superhelix turns are made of parallel beta-strands and (short) turns
  79. 2403751b.82: Double-stranded beta-helix [51181] (7 superfamilies)
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  80. 2406199b.83: Triple beta-spiral [51224] (1 superfamily)
    trimer formed by the interlocking beta-hairpin repeat units
  81. 2406232b.84: Barrel-sandwich hybrid [51229] (5 superfamilies)
    sandwich of half-barrel shaped beta-sheets
  82. 2406647b.85: beta-clip [51268] (7 superfamilies)
    double-stranded ribbon sharply bent in two places; the ribbon ends form incomplete barrel; jelly-roll
  83. 2407441b.86: Hedgehog/intein (Hint) domain [51293] (1 superfamily)
    complex fold made of five beta-hairpin units and a b-ribbon arc
  84. 2407493b.87: LexA/Signal peptidase [51305] (1 superfamily)
    complex fold made of several coiled beta-sheets; contains an SH3-like barrel
  85. 2407553b.88: Mss4-like [51315] (2 superfamilies)
    complex fold made of several coiled beta-sheets
  86. 2407676b.89: Cyanovirin-N [51321] (1 superfamily)
    complex fold
  87. 2407747b.90: Head-binding domain of phage P22 tailspike protein [51326] (1 superfamily)
    complex fold made of bifurcated and partly folded beta-sheet
  88. 2407758b.91: E2 regulatory, transactivation domain [51331] (1 superfamily)
    complex fold made of bifurcated and coiled beta-sheets
  89. 2407781b.92: Composite domain of metallo-dependent hydrolases [51337] (1 superfamily)
    pseudobarrel; mixed sheet of 7 strand folded upon itself and "buckled" by two beta-turns
  90. 2408044b.93: Epsilon subunit of F1F0-ATP synthase N-terminal domain [51343] (1 superfamily)
    pseudobarrel: sandwich of two sheets packed at a positive interstrand angle and interconnected with many short turns
  91. 2408072b.94: Olfactory marker protein [63696] (1 superfamily)
    sandwich; 8 strands in 2 sheets; jelly-roll
  92. 2408085b.95: Ganglioside M2 (gm2) activator [63706] (1 superfamily)
    sandwich; 8 strands in 2 sheets; greek-key: partial topological similarity to immunoglobulin-like folds
  93. 2408110b.96: Nicotinic receptor ligand binding domain-like [63711] (1 superfamily)
    sandwich; 8 strands in 2 sheets; greek-key: partial topological similarity to immunoglobulin-like folds
  94. 2408952b.97: Cytolysin/lectin [63723] (1 superfamily)
    sandwich, 10 strands in 2 sheets;
  95. 2409030b.98: Zn aminopeptidase N-terminal domain [63736] (1 superfamily)
    duplication: two beta-sandwiches of similar topologies are fused together in a single three beta-sheet domain
  96. 2409175b.100: Sortase [63816] (1 superfamily)
    barrel, closed; n=8, S=10; mixed sheet; two overside connections
  97. 2409207b.101: Ribonuclease domain of colicin E3 [63839] (1 superfamily)
    twisted meander beta-sheet of 6 strands
  98. 2409220b.102: Methuselah ectodomain [63876] (1 superfamily)
    complex fold
  99. 2409231b.103: MoeA N-terminal region -like [63881] (1 superfamily)
    complex fold made of bifurcated and coiled b-sheets
  100. 2409290b.104: P-domain of calnexin/calreticulin [63886] (1 superfamily)
    non-globular proline-rich hairpin
  101. 2409301b.105: Penicillin-binding protein associated domain [69188] (1 superfamily)
    sandwich; 6 strands in 2 sheets
  102. 2409351b.106: Phage tail proteins [69278] (1 superfamily)
    core: barrel; n=6, S=10; greek-key; topologically similar to the FMN-binding split barrel
  103. 2409401b.107: Urease metallochaperone UreE, N-terminal domain [69286] (1 superfamily)
    barrel, closed; n=6, S=8; a crossover loop topology
  104. 2409423b.108: Triple-stranded beta-helix [69348] (1 superfamily)
    (homo)trimer; each chain donates 3 beta-strands per turn of the helix
  105. 2409510b.109: beta-hairpin stack [69359] (1 superfamily)
    Trp-rich beta-hairpin repeat units form helical structures of 3 units per turn
  106. 2409544b.110: Cloacin translocation domain [69368] (1 superfamily)
    complex fold made of several coiled beta-sheets
  107. 2409556b.111: Small protein B (SmpB) [74981] (1 superfamily)
    barrel, closed; n=6, S=8, greek-key, partial similarity to the OB-fold
  108. 2409574b.112: C-terminal domain of mollusc hemocyanin [81278] (1 superfamily)
    six-stranded beta-sandwich, jelly-roll/greek-key topology
  109. 2409585b.113: N-terminal domain of MutM-like DNA repair proteins [81625] (1 superfamily)
    pseudobarrel; capped on both ends by alpha-helices
  110. 2409653b.114: N-utilization substance G protein NusG, insert domain [82003] (1 superfamily)
    sandwich; 8 strands in 2 sheets; meander
  111. 2409668b.115: Calcium-mediated lectin [82025] (1 superfamily)
    sandwich; 9 strands in 2 sheets; greek-key
  112. 2409838b.116: Viral chemokine binding protein m3 [82045] (1 superfamily)
    consists of two different beta-sandwich domains of partial topological similarity to immunoglobulin-like folds
  113. 2409851b.117: Obg-fold [82050] (1 superfamily)
    this fold is formed by three glycine-rich regions inserted into a small 8-stranded beta-sandwich
    these regions form six left-handed collagen-like helices packed and H-bonded together
  114. 2409860b.118: FAS1 domain [82152] (1 superfamily)
    core: barrel, closed; n=7, S=12; meander
  115. 2409870b.119: C-terminal autoproteolytic domain of nucleoporin nup98 [82214] (1 superfamily)
    multisheet protein with a mixture of beta-sandwich and beta-prism features
  116. 2409877b.120: Tp47 lipoprotein, N-terminal domain [82219] (1 superfamily)
    complex fold; consists of two intertwined subdomains
  117. 2409884b.121: Nucleoplasmin-like/VP (viral coat and capsid proteins) [88632] (7 superfamilies)
    sandwich; 8 strands in 2 sheets; jelly-roll; some members can have additional 1-2 strands
    characteristic interaction between the domains of this fold allows the formation of five-fold and pseudo six-fold assemblies
  118. 2411564b.122: PUA domain-like [88696] (1 superfamily)
    pseudobarrel; mixed folded sheet of 5 strands; order 13452; strand 1 and 3 are parallel to each other
  119. 2411864b.123: Hypothetical protein TM1070 [89231] (1 superfamily)
    sandwich; 8 strands in 2 sheets; jelly-roll
  120. 2411897b.124: HesB-like domain [89359] (1 superfamily)
    barrel, closed; n=7, S=10; complex topology
  121. 2411926b.125: LolA-like prokaryotic lipoproteins and lipoprotein localization factors [89391] (1 superfamily)
    11 stranded sheet partly folded in a corner-like structure filled with a few short helices
  122. 2411980b.126: Adsorption protein p2 [89427] (1 superfamily)
    multisheet protein containing partial beta-propeller and beta-sandwich regions
  123. 2411987b.127: Baseplate structural protein gp8 [89432] (1 superfamily)
    multisheet protein with a mixture of beta-sandwich and beta-barrel features
  124. 2412004b.128: Hypothetical protein YojF [89441] (1 superfamily)
    pseudobarrel; capped at one end by an alpha-helix
  125. 2412010b.129: Double-split beta-barrel [89446] (2 superfamilies)
    pseudobarrel; capped on both ends by alpha-helices
  126. 2412078b.130: Heat shock protein 70kD (HSP70), peptide-binding domain [100919] (1 superfamily)
    beta-sandwich: 8 strands in 2 sheets
  127. 2412116b.131: SPOC domain-like [100938] (1 superfamily)
    barrel, closed; n=7, S=10; complex topology
  128. 2412132b.132: Supernatant protein factor (SPF), C-terminal domain [101575] (1 superfamily)
    sandwich; 8 strands in 2 sheets; jelly-roll; similarity to the Nucleoplasmin-like/VP fold
  129. 2412149b.133: Dextranase, N-terminal domain [101595] (1 superfamily)
    sandwich; 9 strands in 2 sheets; greek-key
  130. 2412169b.134: Smp-1-like [101600] (1 superfamily)
    sandwich; 9 strands in 2 sheets; greek-key/jelly-roll
  131. 2412178b.135: Superantigen (mitogen) Ypm [101605] (1 superfamily)
    sandwich; 9 strands in 2 sheets; jelly-roll
  132. 2412187b.136: SspB-like [101737] (1 superfamily)
    core: barrel, open; n*=4, S*=8; meander; SH3-like topology; some similarity to the Sm-like fold
  133. 2412233b.137: Rof/RNase P subunit-like [101743] (1 superfamily)
    core: barrel, open; n*=4, S*=8; meander; SH3-like topology; some similarity to the Sm-like fold
  134. 2412252b.138: Hydrophobin II, HfbII [101750] (1 superfamily)
    core: barrel, closed; n=4, S=8; complex topology; helix-containing crossover connection
  135. 2412289b.139: Surface presentation of antigens (SPOA) [101800] (1 superfamily)
    segment-swapped dimer forming two identical conjoint barrels (n=6, S=10) topologically similar to the FMN-binding split barrel
  136. 2412304b.140: Replicase NSP9 [101815] (1 superfamily)
    barrel; n=6, S=8, greek-key; similar to one trypsin-like protease barrel
  137. 2412332b.141: Bacterial fluorinating enzyme, C-terminal domain [101851] (1 superfamily)
    barrel, closed; n=7, S=10; greek-key topology; one overside connection
  138. 2412402b.142: DNA-binding pseudobarrel domain [101935] (1 superfamily)
    core: barrel, open; n=7, S*=10; capped with helices at both ends; partial similarity to the AbrB/MazE/MraZ-like fold (89446)
  139. 2412416b.143: NAC domain [101940] (1 superfamily)
    core: twisted 7-stranded beta-sheet (half-barrel)
  140. 2412430b.144: Trimeric adhesin [101998] (1 superfamily)
    trimer; contains two different beta-prism-like domains connected by an linker subdomain of less regular structure
  141. 2412441b.145: AXH domain [102030] (1 superfamily)
    pseudobarrel; some similarity to OB-fold
  142. 2412473b.146: Ctag/Cox11 [110110] (1 superfamily)
    sandwich; 7 strands in 2 sheets, greek-key; permutation of the immunoglobulin-like fold
  143. 2412480b.147: BTV NS2-like ssRNA-binding domain [110131] (1 superfamily)
    sandwich; 9 strands in 2 sheets; unusual topology with 2 crossover loops
  144. 2412487b.148: Coronavirus RNA-binding domain [110303] (1 superfamily)
    coiled antiparallel beta-sheet of 5 strands, order 51324; complex topology, crossing loops
  145. 2412502b.149: Beta-galactosidase LacA, domain 3 [117099] (1 superfamily)
    sandwich; 8 strands in 2 sheets
  146. 2412525b.150: Glycolsyl hydrolase family 31 C-terminal domain-like [117124] (1 superfamily)
    sandwich; 10 strands in two sheets
  147. 2412587b.151: CsrA-like [117129] (1 superfamily)
    sandwich; 10 strands in 2 sheets; intertwined dimer (segment-swapped, 5-stranded greek-key sandwich?)
  148. 2412633b.152: Flagellar hook protein flgE [117142] (1 superfamily)
    consists of two different domains; d1: [complex fold made of bifurcated beta-sheets]; d2 (inserted into d1): [beta-sandwich; 8 strands in 2 sheets]
  149. 2412640b.153: PheT/TilS domain [56036] (1 superfamily)
    core: 3 layers; contains beta-sandwich of unusual topology
  150. 2412661b.154: HPA-like [141085] (1 superfamily)
    sandwich, 6 strands in 2 sheets; jelly-roll (truncated); also includes the pending PCSK9 V domain-like superfamily (the C-terminal domains of 2p4e and 2pmw)
  151. 2412674b.155: L21p-like [141090] (1 superfamily)
    core: sandwich, 6 strands in 2 sheets
  152. 2412729b.156: Atu1913-like [141098] (1 superfamily)
    sandwich; 7 strands in two sheets, greek-key/jelly-roll; forms segment swapped dimers, swapping is probably facilitated by the helix insertion after strand 3
  153. 2412735b.157: Hcp1-like [141451] (1 superfamily)
    barrel, closed; n=6, S=12; contains extra, non-barrel strand 7 at the C-terminus
  154. 2412766b.158: BH3618-like [141456] (1 superfamily)
    barrel, closed; n=7, S=10; meander
  155. 2412773b.159: AOC barrel-like [141492] (2 superfamilies)
    barrel, closed; n=8, S=10; meander; mirrored (reversed) topology to the Spreptavidin-like and Lipocalin-like folds
  156. 2412856b.160: L,D-transpeptidase catalytic domain-like [141522] (1 superfamily)
    barrel, closed; n=8, S=10; one overside connection
  157. 2412885b.161: PTSIIA/GutA-like [141529] (1 superfamily)
    barrel, closed; n=8, S=12; mixed sheet; two overside connections; duplication: consists of two intertwinned structural repeats
  158. 2412894b.162: At5g01610-like [141561] (1 superfamily)
    contains large meander beta-sheet bent into a scoop-like shape
  159. 2412900b.163: Pseudo beta-prism I [141657] (1 superfamily)
    beta-sandwich with one regular beta-sheet and the other beta-sheet bent in the middle with a set of aligned beta-bulges
  160. 2412927b.164: SARS ORF9b-like [141665] (1 superfamily)
    complex dimeric fold with three intersubunit beta-sheets packed around a single core
  161. 2412940b.165: MOSC N-terminal domain-like [141672] (1 superfamily)
    complex fold; comprises a beta-hairpin and a meander 3-stranded sheet packed against beta-barrel: closed, n=5, S=8; contains three short helices
  162. 2412947b.166: MAL13P1.257-like [141677] (1 superfamily)
    complex fold; duplication: consists of two intertwinned structural repeats related by pseudo dyad
  163. 2412954b.167: FimD N-terminal domain-like [141728] (1 superfamily)
    pseudo barrel, capped by an alpha-helix; some topological similarity to the PRC-barrel domain (50346) and the N-terminal domain of Glutamine synthetase (54368)
  164. 2412968b.168: HisI-like [141733] (1 superfamily)
    pseudo barrel, capped by an alpha-helix; contains a beta-triangle structure on one side; some topological similarity to the Ribosomal protein L25-like fold (50714) and the N-terminal domain of Glutamine synthetase (54368)
  165. 2412975b.169: MFPT repeat-like [141738] (1 superfamily)
    consists of two similar pseudo barrel subdomains with structural similarity to a circularly permuted SAND domain (63764)
  166. 2412987b.170: WSSV envelope protein-like [158973] (1 superfamily)
    beta-sandwich; 9 strands in 2 sheets; greek-key
  167. 2413007b.171: Trm112p-like [158996] (1 superfamily)
    similar to the small domain of the ISP (50021)
  168. 2413027b.172: YopX-like [159005] (1 superfamily)
    consists of two domains: the N-terminal dimerisation domain of variable structure and the C-terminal domain with similarity to the SH3-like fold
  169. 2413048b.173: NifT/FixU barrel-like [159202] (1 superfamily)
    barrel, closed, n=6, S=10; meander
  170. 2413054b.174: YopT-like [159221] (1 superfamily)
    beta-sheet barrel, closed, n=6, S=12, capped at both ends by helices; intertwined dimer of beta-alpha-beta(2) subinits;
  171. 2413063b.175: FomD barrel-like [159233] (1 superfamily)
    barrel, closed; n=8, S=12; meander; similar topology to the AOC barrel-like fold (reversed to the lipocalin barrel topology)
  172. 2413070b.176: AttH-like [159244] (1 superfamily)
    duplication: two flattened beta-barrels of lipocalin-like topology are orthogonally packed with a pseudo twofold symmetry
  173. 2413077b.177: YmcC-like [159269] (1 superfamily)
    12-stranded meander beta-sheet, folded into a deformed beta-barrel; topological similarity to the LolA-like fold (89391)
  174. 2413084b.178: Spiral beta-roll [159274] (1 superfamily)
    a large 15-stranded beta-sheet rolled about a single helix core; overlapping edges form a sandwich-like structure; topological similarity to the LolA-like fold (89391)
  175. 2413091b.179: Anthrax protective antigen N-terminal-like [254104] (1 superfamily)
    core: sandwich; 10-12 strands in 2 sheets; jelly roll; may contain inserted subdomains
  176. 2413164b.180: Pseudo beta-prism II [254120] (1 superfamily)
    sandwich with one 5-strand antiparallel beta-sheet and a 5-strand mixed beta-sheet bent in the middle with a set of aligned beta-bulges and/or strand breaks; disulfide linked
  177. 2413175b.181: Handle domain of Transferrin binding protein TbpB-like [310564] (1 superfamily)
    2 layers; antiparallel B-sheet, order 1432 or 216543, flanked by alpha helix or 2-strand beta hairpin
  178. 2413212b.182: U5 small nuclear riboprotein particle assembly factor Aar2 N-terminal domain-like [345889] (1 superfamily)
    10-stranded mixed beta sandwich with 3 helices surrounding the upper rim

More info for Class b: All beta proteins

Timeline for Class b: All beta proteins: