Lineage for Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2108258Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 2108259Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 2108535Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module [88749] (8 protein domains)
    the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology

Protein Domains:

  1. 2108536Acetohydroxyacid synthase catalytic subunit [88758] (3 species)
    1. 2108537Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88759] (6 PDB entries)
      Uniprot P07342 84-687
    2. 2108552Species Thale cress (Arabidopsis thaliana), chloroplast [TaxId:3702] [142208] (11 PDB entries)
      Uniprot P17597 460-667
    3. 2270805Species Saccharomyces cerevisiae [TaxId:559292] [314110] (1 PDB entry)
  2. 2108559Benzoylformate decarboxylase [88756] (1 species)
  3. 2108583Carboxyethylarginine synthase [102335] (1 species)
  4. 2108611Catabolic acetolactate synthase [102333] (1 species)
  5. 2108621Indole-3-pyruvate decarboxylase [89654] (1 species)
  6. 2108627Oxalyl-CoA decarboxylase [142209] (1 species)
  7. 2108641Pyruvate decarboxylase [88750] (3 species)
    1. 2108642Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88752] (2 PDB entries)
    2. 2108647Species Brewer's yeast (Saccharomyces uvarum) [TaxId:230603] [88751] (1 PDB entry)
    3. 2108650Species Zymomonas mobilis [TaxId:542] [88753] (1 PDB entry)
  8. 2108655Pyruvate oxidase [88754] (2 species)
    1. 2108656Species Aerococcus viridans [TaxId:1377] [142207] (2 PDB entries)
    2. Species Lactobacillus plantarum [TaxId:1590] [88755] (2 PDB entries)

More info for Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module

Timeline for Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module: