Lineage for Protein: Acetohydroxyacid synthase catalytic subunit

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2445862Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 2445863Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 2446153Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module [88749] (8 protein domains)
    the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology
  6. 2446154Protein Acetohydroxyacid synthase catalytic subunit [88758] (3 species)

Species:

  1. 2446155Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88759] (8 PDB entries)
    Uniprot P07342 84-687
    1. Domains for 1jsc:
      1. 2446156Domain d1jsca3: 1jsc A:461-648 [67226]
        Other proteins in same PDB: d1jsca1, d1jsca2, d1jscb1, d1jscb2
        complexed with 2hp, fad, k, mg, tpp
      2. 2446157Domain d1jscb3: 1jsc B:464-649 [67229]
        Other proteins in same PDB: d1jsca1, d1jsca2, d1jscb1, d1jscb2
        complexed with 2hp, fad, k, mg, tpp
    2. Domains for 1n0h:
      1. 2446172Domain d1n0ha3: 1n0h A:461-687 [79736]
        Other proteins in same PDB: d1n0ha1, d1n0ha2, d1n0hb1, d1n0hb2
        complexed with ayd, cie, dtt, fad, k, mg, tpp
      2. 2446173Domain d1n0hb3: 1n0h B:461-687 [79739]
        Other proteins in same PDB: d1n0ha1, d1n0ha2, d1n0hb1, d1n0hb2
        complexed with ayd, cie, dtt, fad, k, mg, tpp
    3. Domains for 1t9a:
      1. 2446170Domain d1t9aa3: 1t9a A:461-687 [112330]
        Other proteins in same PDB: d1t9aa1, d1t9aa2, d1t9ab1, d1t9ab2
        complexed with 1tb, fad, k, mg, p23, yf3, yf4
      2. 2446171Domain d1t9ab3: 1t9a B:461-687 [112333]
        Other proteins in same PDB: d1t9aa1, d1t9aa2, d1t9ab1, d1t9ab2
        complexed with 1tb, fad, k, mg, p23, yf3, yf4
    4. Domains for 1t9b:
      1. 2446160Domain d1t9ba3: 1t9b A:461-687 [112336]
        Other proteins in same PDB: d1t9ba1, d1t9ba2, d1t9bb1, d1t9bb2
        complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3
      2. 2446161Domain d1t9bb3: 1t9b B:461-687 [112339]
        Other proteins in same PDB: d1t9ba1, d1t9ba2, d1t9bb1, d1t9bb2
        complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3
    5. Domains for 1t9c:
      1. 2446168Domain d1t9ca3: 1t9c A:461-687 [112342]
        Other proteins in same PDB: d1t9ca1, d1t9ca2, d1t9cb1, d1t9cb2
        complexed with 1sm, fad, k, mg, p22, p23
      2. 2446169Domain d1t9cb3: 1t9c B:461-687 [112345]
        Other proteins in same PDB: d1t9ca1, d1t9ca2, d1t9cb1, d1t9cb2
        complexed with 1sm, fad, k, mg, p22, p23
    6. Domains for 1t9d:
      1. 2446164Domain d1t9da3: 1t9d A:461-687 [112348]
        Other proteins in same PDB: d1t9da1, d1t9da2, d1t9db1, d1t9db2, d1t9dc1, d1t9dc2, d1t9dd1, d1t9dd2
        complexed with 1mm, fad, k, mg, p22, p25, pyd
      2. 2446165Domain d1t9db3: 1t9d B:461-687 [112351]
        Other proteins in same PDB: d1t9da1, d1t9da2, d1t9db1, d1t9db2, d1t9dc1, d1t9dc2, d1t9dd1, d1t9dd2
        complexed with 1mm, fad, k, mg, p22, p25, pyd
      3. 2446166Domain d1t9dc3: 1t9d C:461-687 [112354]
        Other proteins in same PDB: d1t9da1, d1t9da2, d1t9db1, d1t9db2, d1t9dc1, d1t9dc2, d1t9dd1, d1t9dd2
        complexed with 1mm, fad, k, mg, p22, p25, pyd
      4. 2446167Domain d1t9dd3: 1t9d D:461-687 [112357]
        Other proteins in same PDB: d1t9da1, d1t9da2, d1t9db1, d1t9db2, d1t9dc1, d1t9dc2, d1t9dd1, d1t9dd2
        complexed with 1mm, fad, k, mg, p22, p25, pyd
    7. Domains for 6bd3:
      1. 2446162Domain d6bd3a3: 6bd3 A:461-648 [344489]
        Other proteins in same PDB: d6bd3a1, d6bd3a2, d6bd3b1, d6bd3b2
        complexed with act, co2, fad, htl, k, mg, oxy, po4, tpp
      2. 2446163Domain d6bd3b3: 6bd3 B:461-649 [344490]
        Other proteins in same PDB: d6bd3a1, d6bd3a2, d6bd3b1, d6bd3b2
        complexed with act, co2, fad, htl, k, mg, oxy, po4, tpp
    8. Domains for 6bd9:
      1. 2446158Domain d6bd9a3: 6bd9 A:461-648 [344491]
        Other proteins in same PDB: d6bd9a1, d6bd9a2, d6bd9b1, d6bd9b2
        complexed with fad, k, mg, oxy, po4, pyr, tpp
      2. 2446159Domain d6bd9b3: 6bd9 B:461-646 [344492]
        Other proteins in same PDB: d6bd9a1, d6bd9a2, d6bd9b1, d6bd9b2
        complexed with fad, k, mg, oxy, po4, pyr, tpp
  2. 2446174Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [314110] (3 PDB entries)
    1. Domains for 5fem:
      1. 2446177Domain d5fema3: 5fem A:461-687 [314123]
        Other proteins in same PDB: d5fema1, d5fema2, d5femb1, d5femb2
        automated match to d1n0ha3
        complexed with 60g, fad, mg, tpp
      2. 2446178Domain d5femb3: 5fem B:461-687 [314111]
        Other proteins in same PDB: d5fema1, d5fema2, d5femb1, d5femb2
        automated match to d1n0ha3
        complexed with 60g, fad, mg, tpp
    2. Domains for 5ims:
      1. 2446175Domain d5imsa3: 5ims A:461-647 [344276]
        Other proteins in same PDB: d5imsa1, d5imsa2, d5imsb1, d5imsb2
        complexed with act, fad, k, mg, oxy, po4, tpp
      2. 2446176Domain d5imsb3: 5ims B:461-647 [344277]
        Other proteins in same PDB: d5imsa1, d5imsa2, d5imsb1, d5imsb2
        complexed with act, fad, k, mg, oxy, po4, tpp
    3. Domains for 5wkc:
      1. 3048136Domain d5wkca3: 5wkc A:461-687 [348198]
        Other proteins in same PDB: d5wkca1, d5wkca2, d5wkcb1, d5wkcb2, d5wkcd1, d5wkcd2, d5wkce1, d5wkce2
        automated match to d1n0ha3
        complexed with auj, f50, fad, mg, pxd, tp9
      2. 3048156Domain d5wkcd3: 5wkc D:461-687 [348218]
        Other proteins in same PDB: d5wkca1, d5wkca2, d5wkcb1, d5wkcb2, d5wkcd1, d5wkcd2, d5wkce1, d5wkce2
        automated match to d1n0ha3
        complexed with auj, f50, fad, mg, pxd, tp9
      3. 3048242Domain d5wkce3: 5wkc E:461-687 [348304]
        Other proteins in same PDB: d5wkca1, d5wkca2, d5wkcb1, d5wkcb2, d5wkcd1, d5wkcd2, d5wkce1, d5wkce2
        automated match to d1n0ha3
        complexed with auj, f50, fad, mg, pxd, tp9
      4. 3048286Domain d5wkcb3: 5wkc B:461-687 [348348]
        Other proteins in same PDB: d5wkca1, d5wkca2, d5wkcb1, d5wkcb2, d5wkcd1, d5wkcd2, d5wkce1, d5wkce2
        automated match to d1n0ha3
        complexed with auj, f50, fad, mg, pxd, tp9
  3. 2446179Thale cress (Arabidopsis thaliana), chloroplast [TaxId:3702] [142208] (12 PDB entries)
    Uniprot P17597 460-667
    1. Domain for 1ybh:
    2. Domain for 1yhy:
    3. Domain for 1yhz:
    4. Domain for 1yi0:
    5. Domain for 1yi1:
    6. Domain for 1z8n:
    7. Domain for 5k2o:
    8. Domain for 5k3s:
    9. Domain for 5k6q:
    10. Domain for 5k6r:
    11. Domain for 5k6t:
    12. Domain for 5wj1:

More info for Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.9: Pyruvate oxidase and decarboxylase PP module

Timeline for Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.9: Pyruvate oxidase and decarboxylase PP module:

  • Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.9: Pyruvate oxidase and decarboxylase PP module first appeared in SCOP 1.65
  • Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.9: Pyruvate oxidase and decarboxylase PP module appears in SCOPe 2.06