Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465 |
Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules |
Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module [88749] (8 proteins) the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology |
Protein Acetohydroxyacid synthase catalytic subunit [88758] (3 species) |
Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88759] (8 PDB entries) Uniprot P07342 84-687 |
Domain d1jsca3: 1jsc A:461-648 [67226] Other proteins in same PDB: d1jsca1, d1jsca2, d1jscb1, d1jscb2 complexed with 2hp, fad, k, mg, tpp |
Domain d1jscb3: 1jsc B:464-649 [67229] Other proteins in same PDB: d1jsca1, d1jsca2, d1jscb1, d1jscb2 complexed with 2hp, fad, k, mg, tpp |
Domain d1n0ha3: 1n0h A:461-687 [79736] Other proteins in same PDB: d1n0ha1, d1n0ha2, d1n0hb1, d1n0hb2 complexed with ayd, cie, dtt, fad, k, mg, tpp |
Domain d1n0hb3: 1n0h B:461-687 [79739] Other proteins in same PDB: d1n0ha1, d1n0ha2, d1n0hb1, d1n0hb2 complexed with ayd, cie, dtt, fad, k, mg, tpp |
Domain d1t9aa3: 1t9a A:461-687 [112330] Other proteins in same PDB: d1t9aa1, d1t9aa2, d1t9ab1, d1t9ab2 complexed with 1tb, fad, k, mg, p23, yf3, yf4 |
Domain d1t9ab3: 1t9a B:461-687 [112333] Other proteins in same PDB: d1t9aa1, d1t9aa2, d1t9ab1, d1t9ab2 complexed with 1tb, fad, k, mg, p23, yf3, yf4 |
Domain d1t9ba3: 1t9b A:461-687 [112336] Other proteins in same PDB: d1t9ba1, d1t9ba2, d1t9bb1, d1t9bb2 complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3 |
Domain d1t9bb3: 1t9b B:461-687 [112339] Other proteins in same PDB: d1t9ba1, d1t9ba2, d1t9bb1, d1t9bb2 complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3 |
Domain d1t9ca3: 1t9c A:461-687 [112342] Other proteins in same PDB: d1t9ca1, d1t9ca2, d1t9cb1, d1t9cb2 complexed with 1sm, fad, k, mg, p22, p23 |
Domain d1t9cb3: 1t9c B:461-687 [112345] Other proteins in same PDB: d1t9ca1, d1t9ca2, d1t9cb1, d1t9cb2 complexed with 1sm, fad, k, mg, p22, p23 |
Domain d1t9da3: 1t9d A:461-687 [112348] Other proteins in same PDB: d1t9da1, d1t9da2, d1t9db1, d1t9db2, d1t9dc1, d1t9dc2, d1t9dd1, d1t9dd2 complexed with 1mm, fad, k, mg, p22, p25, pyd |
Domain d1t9db3: 1t9d B:461-687 [112351] Other proteins in same PDB: d1t9da1, d1t9da2, d1t9db1, d1t9db2, d1t9dc1, d1t9dc2, d1t9dd1, d1t9dd2 complexed with 1mm, fad, k, mg, p22, p25, pyd |
Domain d1t9dc3: 1t9d C:461-687 [112354] Other proteins in same PDB: d1t9da1, d1t9da2, d1t9db1, d1t9db2, d1t9dc1, d1t9dc2, d1t9dd1, d1t9dd2 complexed with 1mm, fad, k, mg, p22, p25, pyd |
Domain d1t9dd3: 1t9d D:461-687 [112357] Other proteins in same PDB: d1t9da1, d1t9da2, d1t9db1, d1t9db2, d1t9dc1, d1t9dc2, d1t9dd1, d1t9dd2 complexed with 1mm, fad, k, mg, p22, p25, pyd |
Domain d6bd3a3: 6bd3 A:461-648 [344489] Other proteins in same PDB: d6bd3a1, d6bd3a2, d6bd3b1, d6bd3b2 complexed with act, co2, fad, htl, k, mg, oxy, po4, tpp |
Domain d6bd3b3: 6bd3 B:461-649 [344490] Other proteins in same PDB: d6bd3a1, d6bd3a2, d6bd3b1, d6bd3b2 complexed with act, co2, fad, htl, k, mg, oxy, po4, tpp |
Domain d6bd9a3: 6bd9 A:461-648 [344491] Other proteins in same PDB: d6bd9a1, d6bd9a2, d6bd9b1, d6bd9b2 complexed with fad, k, mg, oxy, po4, pyr, tpp |
Domain d6bd9b3: 6bd9 B:461-646 [344492] Other proteins in same PDB: d6bd9a1, d6bd9a2, d6bd9b1, d6bd9b2 complexed with fad, k, mg, oxy, po4, pyr, tpp |
Timeline for Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] from c.36.1.9 Acetohydroxyacid synthase catalytic subunit: