Lineage for Protein: Pyruvate oxidase

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2108258Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 2108259Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 2108535Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module [88749] (8 protein domains)
    the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology
  6. 2108655Protein Pyruvate oxidase [88754] (2 species)

Species:

  1. 2108656Aerococcus viridans [TaxId:1377] [142207] (2 PDB entries)
    1. Domain for 1v5e:
    2. Domain for 2dji:
  2. Lactobacillus plantarum [TaxId:1590] [88755] (2 PDB entries)
    1. Domains for 1pow:
      1. 2108662Domain d1powa3: 1pow A:366-593 [31798]
        Other proteins in same PDB: d1powa1, d1powa2, d1powb1, d1powb2
        complexed with fad, mg, tpp; mutant
      2. 2108663Domain d1powb3: 1pow B:366-593 [31800]
        Other proteins in same PDB: d1powa1, d1powa2, d1powb1, d1powb2
        complexed with fad, mg, tpp; mutant
    2. Domains for 1pox:
      1. 2108660Domain d1poxa3: 1pox A:366-593 [31794]
        Other proteins in same PDB: d1poxa1, d1poxa2, d1poxb1, d1poxb2
        complexed with fad, gol, mg, na, tpp; mutant
      2. 2108661Domain d1poxb3: 1pox B:366-593 [31796]
        Other proteins in same PDB: d1poxa1, d1poxa2, d1poxb1, d1poxb2
        complexed with fad, gol, mg, na, tpp; mutant

More info for Protein Pyruvate oxidase from c.36.1.9: Pyruvate oxidase and decarboxylase PP module

Timeline for Protein Pyruvate oxidase from c.36.1.9: Pyruvate oxidase and decarboxylase PP module: