Lineage for Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module

  1. Root: SCOP 1.65
  2. 305035Class c: Alpha and beta proteins (a/b) [51349] (121 folds)
  3. 312976Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 312977Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 313084Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module [88749] (5 proteins)
    the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology

Proteins:

  1. 313085Acetohydroxyacid synthase catalytic subunit [88758] (1 species)
  2. 313091Benzoylformate decarboxylase [88756] (1 species)
  3. 313110Indole-3-pyruvate decarboxylase [89654] (1 species)
  4. 313116Pyruvate decarboxylase [88750] (3 species)
    1. 313117Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88752] (2 PDB entries)
    2. 313122Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] [88751] (1 PDB entry)
    3. 313125Species Zymomonas mobilis [TaxId:542] [88753] (1 PDB entry)
  5. 313130Pyruvate oxidase [88754] (1 species)

More info for Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module

Timeline for Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module: