Lineage for Family d.153.1.4: Proteasome subunits

  1. Root: SCOP 1.63
  2. 251695Class d: Alpha and beta proteins (a+b) [53931] (224 folds)
  3. 263343Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 263344Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (5 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 263459Family d.153.1.4: Proteasome subunits [56251] (3 proteins)

Proteins:

  1. 263460HslV (ClpQ) protease [56258] (2 species)
    dodecameric prokaryotic homologue of proteasome
    1. 263461Species Escherichia coli [TaxId:562] [56259] (7 PDB entries)
    2. 263497Species Haemophilus influenzae [TaxId:727] [56260] (4 PDB entries)
  2. 263528Proteasome alpha subunit (non-catalytic) [56255] (3 species)
    contains an extension to the common fold at the N-teminus
    1. 263529Species Archaeon Thermoplasma acidophilum [TaxId:2303] [56256] (1 PDB entry)
    2. 263544Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56257] (4 PDB entries)
      The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
    3. 263601Species Cow (Bos taurus) [TaxId:9913] [75568] (1 PDB entry)
  3. 263616Proteasome beta subunit (catalytic) [56252] (3 species)
    1. 263617Species Archaeon Thermoplasma acidophilum [TaxId:2303] [56253] (1 PDB entry)
    2. 263632Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56254] (4 PDB entries)
      The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
    3. 263689Species Cow (Bos taurus) [TaxId:9913] [75567] (1 PDB entry)

More info for Family d.153.1.4: Proteasome subunits

Timeline for Family d.153.1.4: Proteasome subunits: