Lineage for Family d.153.1.4: Proteasome subunits

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2988339Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 2988340Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 2988529Family d.153.1.4: Proteasome subunits [56251] (4 proteins)

Proteins:

  1. 2988530HslV (ClpQ) protease [56258] (4 species)
    dodecameric prokaryotic homologue of proteasome
    1. 2988531Species Bacillus subtilis [TaxId:1423] [160845] (2 PDB entries)
      Uniprot P39070 2-181
    2. 2988546Species Escherichia coli [TaxId:562] [56259] (8 PDB entries)
    3. 2988594Species Haemophilus influenzae [TaxId:727] [56260] (6 PDB entries)
    4. 2988637Species Thermotoga maritima [TaxId:2336] [90045] (1 PDB entry)
  2. 2988641Proteasome alpha subunit (non-catalytic) [56255] (10 species)
    contains an extension to the common fold at the N-terminus
    1. 2988642Species Archaeoglobus fulgidus [TaxId:2234] [90044] (2 PDB entries)
    2. 2988657Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56257] (240 PDB entries)
      The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
    3. 2990638Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [256264] (12 PDB entries)
    4. 2990734Species Cow (Bos taurus) [TaxId:9913] [75568] (1 PDB entry)
    5. 2990749Species Human (Homo sapiens) [TaxId:9606] [311422] (15 PDB entries)
    6. 2990863Species Methanocaldococcus jannaschii [TaxId:2190] [346387] (1 PDB entry)
      3h4p lower case chains a-g are beta subunits; not included because sids are not case sensitive
    7. 2990871Species Mouse (Mus musculus) [TaxId:10090] [195927] (2 PDB entries)
    8. 2990876Species Norway rat (Rattus norvegicus) [TaxId:10116] [385589] (1 PDB entry)
    9. 2990879Species Rhodococcus erythropolis [TaxId:1833] [103314] (3 PDB entries)
    10. 2990901Species Thermoplasma acidophilum [TaxId:2303] [56256] (8 PDB entries)
  3. 2990986Proteasome beta subunit (catalytic) [56252] (7 species)
    1. 2990987Species Archaeoglobus fulgidus [TaxId:2234] [90043] (1 PDB entry)
    2. 2990995Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56254] (202 PDB entries)
      The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
    3. 2993094Species Cow (Bos taurus) [TaxId:9913] [75567] (1 PDB entry)
    4. 2993109Species Human (Homo sapiens) [TaxId:9606] [311421] (15 PDB entries)
    5. 2993197Species Methanocaldococcus jannaschii [TaxId:2190] [346388] (1 PDB entry)
      3h4p upper case chains H-N are alpha subunits; not included because sids are not case sensitive
    6. 2993205Species Rhodococcus erythropolis [TaxId:1833] [103313] (3 PDB entries)
    7. 2993227Species Thermoplasma acidophilum [TaxId:2303] [56253] (7 PDB entries)
  4. 2993312automated matches [190144] (14 species)
    not a true protein
    1. 2993313Species Bacillus anthracis [TaxId:198094] [189742] (1 PDB entry)
    2. 2993320Species Bacillus subtilis [TaxId:1423] [187296] (1 PDB entry)
    3. 2993333Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [187078] (41 PDB entries)
    4. 2993581Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [189752] (202 PDB entries)
    5. 2995053Species Escherichia coli [311130] (1 PDB entry)
    6. 2995058Species Escherichia coli [TaxId:562] [326970] (1 PDB entry)
    7. 2995063Species Human (Homo sapiens) [TaxId:9606] [311423] (25 PDB entries)
    8. 2995169Species Mouse (Mus musculus) [TaxId:10090] [195917] (3 PDB entries)
    9. 2995215Species Mycobacterium tuberculosis [TaxId:1773] [187707] (16 PDB entries)
    10. 2995626Species Mycobacterium tuberculosis [TaxId:419947] [328158] (1 PDB entry)
    11. 2995653Species Mycobacterium tuberculosis [TaxId:83332] [375714] (3 PDB entries)
    12. 2995732Species Norway rat (Rattus norvegicus) [TaxId:10116] [385575] (1 PDB entry)
    13. 2995743Species Staphylococcus aureus [TaxId:158878] [389232] (2 PDB entries)
    14. 2995759Species Thermoplasma acidophilum [TaxId:2303] [186869] (4 PDB entries)

More info for Family d.153.1.4: Proteasome subunits

Timeline for Family d.153.1.4: Proteasome subunits: