Lineage for Family d.153.1.4: Proteasome subunits

  1. Root: SCOPe 2.07
  2. 2530962Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2594580Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 2594581Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 2594772Family d.153.1.4: Proteasome subunits [56251] (4 proteins)

Proteins:

  1. 2594773HslV (ClpQ) protease [56258] (4 species)
    dodecameric prokaryotic homologue of proteasome
    1. 2594774Species Bacillus subtilis [TaxId:1423] [160845] (2 PDB entries)
      Uniprot P39070 2-181
    2. 2594789Species Escherichia coli [TaxId:562] [56259] (8 PDB entries)
    3. 2594837Species Haemophilus influenzae [TaxId:727] [56260] (6 PDB entries)
    4. 2594880Species Thermotoga maritima [TaxId:2336] [90045] (1 PDB entry)
  2. 2594884Proteasome alpha subunit (non-catalytic) [56255] (10 species)
    contains an extension to the common fold at the N-terminus
    1. 2594885Species Archaeoglobus fulgidus [TaxId:2234] [90044] (2 PDB entries)
    2. 2594900Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56257] (242 PDB entries)
      The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
    3. 2596886Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [256264] (12 PDB entries)
    4. 2596982Species Cow (Bos taurus) [TaxId:9913] [75568] (1 PDB entry)
    5. 2596997Species Human (Homo sapiens) [TaxId:9606] [311422] (14 PDB entries)
    6. 2597106Species Methanocaldococcus jannaschii [TaxId:2190] [346387] (1 PDB entry)
      3h4p lower case chains a-g are beta subunits; not included because sids are not case sensitive
    7. 2597114Species Mouse (Mus musculus) [TaxId:10090] [195927] (2 PDB entries)
    8. 2597119Species Rattus norvegicus [TaxId:10116] [385589] (1 PDB entry)
    9. 2597122Species Rhodococcus erythropolis [TaxId:1833] [103314] (3 PDB entries)
    10. 2597144Species Thermoplasma acidophilum [TaxId:2303] [56256] (4 PDB entries)
  3. 2597201Proteasome beta subunit (catalytic) [56252] (7 species)
    1. 2597202Species Archaeoglobus fulgidus [TaxId:2234] [90043] (1 PDB entry)
    2. 2597210Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56254] (202 PDB entries)
      The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
    3. 2599309Species Cow (Bos taurus) [TaxId:9913] [75567] (1 PDB entry)
    4. 2599324Species Human (Homo sapiens) [TaxId:9606] [311421] (14 PDB entries)
    5. 2599406Species Methanocaldococcus jannaschii [TaxId:2190] [346388] (1 PDB entry)
      3h4p upper case chains H-N are alpha subunits; not included because sids are not case sensitive
    6. 2599414Species Rhodococcus erythropolis [TaxId:1833] [103313] (3 PDB entries)
    7. 2599436Species Thermoplasma acidophilum [TaxId:2303] [56253] (7 PDB entries)
  4. 2599521automated matches [190144] (14 species)
    not a true protein
    1. 2599522Species Bacillus anthracis [TaxId:198094] [189742] (1 PDB entry)
    2. 2599529Species Bacillus subtilis [TaxId:1423] [187296] (1 PDB entry)
    3. 2599542Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [187078] (41 PDB entries)
    4. 2599790Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [189752] (203 PDB entries)
    5. 2601263Species Escherichia coli [311130] (1 PDB entry)
    6. 2601268Species Escherichia coli [TaxId:562] [326970] (1 PDB entry)
    7. 2601273Species Human (Homo sapiens) [TaxId:9606] [311423] (24 PDB entries)
    8. 2601384Species Mouse (Mus musculus) [TaxId:10090] [195917] (3 PDB entries)
    9. 2601430Species Mycobacterium tuberculosis [TaxId:1773] [187707] (15 PDB entries)
    10. 2601841Species Mycobacterium tuberculosis [TaxId:419947] [328158] (1 PDB entry)
    11. 2601868Species Mycobacterium tuberculosis [TaxId:83332] [375714] (3 PDB entries)
    12. 2601947Species Rattus norvegicus [TaxId:10116] [385575] (1 PDB entry)
    13. 2601958Species Staphylococcus aureus [TaxId:158878] [389232] (2 PDB entries)
    14. 2601974Species Thermoplasma acidophilum [TaxId:2303] [186869] (8 PDB entries)

More info for Family d.153.1.4: Proteasome subunits

Timeline for Family d.153.1.4: Proteasome subunits: