SCOPe 2.08: Fold d.153: Ntn hydrolase-like

Lineage for Fold d.153: Ntn hydrolase-like

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
   4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing

Superfamilies:

1. d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families)
   N-terminal residue provides two catalytic groups, nucleophile and proton donor

2. d.153.2: Archaeal IMP cyclohydrolase PurO [75569] (1 family)
   has a putative active site in the same topological location as the Ntn hydrolase but lacks the N-terminal nucleophile
   automatically mapped to Pfam PF07826

More info for Fold d.153: Ntn hydrolase-like

Timeline for Fold d.153: Ntn hydrolase-like:

• Fold d.153: Ntn hydrolase-like first appeared (with stable ids) in SCOP 1.55, called Fold d.153: N-terminal nucleophile aminohydrolases (Ntn hydrolases)
  
• Fold d.153: Ntn hydrolase-like appears in SCOPe 2.07