Lineage for Family d.153.1.4: Proteasome subunits

  1. Root: SCOP 1.65
  2. 323018Class d: Alpha and beta proteins (a+b) [53931] (234 folds)
  3. 335536Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 335537Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (5 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 335658Family d.153.1.4: Proteasome subunits [56251] (3 proteins)

Proteins:

  1. 335659HslV (ClpQ) protease [56258] (3 species)
    dodecameric prokaryotic homologue of proteasome
    1. 335660Species Escherichia coli [TaxId:562] [56259] (7 PDB entries)
    2. 335696Species Haemophilus influenzae [TaxId:727] [56260] (6 PDB entries)
    3. 335739Species Thermotoga maritima [TaxId:243274] [90045] (1 PDB entry)
  2. 335743Proteasome alpha subunit (non-catalytic) [56255] (4 species)
    contains an extension to the common fold at the N-teminus
    1. 335744Species Archaeon Archaeoglobus fulgidus [TaxId:2234] [90044] (2 PDB entries)
    2. 335759Species Archaeon Thermoplasma acidophilum [TaxId:2303] [56256] (1 PDB entry)
    3. 335774Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56257] (4 PDB entries)
      The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
    4. 335831Species Cow (Bos taurus) [TaxId:9913] [75568] (1 PDB entry)
  3. 335846Proteasome beta subunit (catalytic) [56252] (4 species)
    1. 335847Species Archaeon Archaeoglobus fulgidus [TaxId:2234] [90043] (1 PDB entry)
    2. 335855Species Archaeon Thermoplasma acidophilum [TaxId:2303] [56253] (1 PDB entry)
    3. 335870Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56254] (4 PDB entries)
      The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
    4. 335927Species Cow (Bos taurus) [TaxId:9913] [75567] (1 PDB entry)

More info for Family d.153.1.4: Proteasome subunits

Timeline for Family d.153.1.4: Proteasome subunits: