Lineage for Family d.20.1.1: UBC-related

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.20: UBC-like [54494] (1 superfamily)
    alpha-beta(4)-alpha(3); core: meander beta-sheet plus one helix 2
  4. Superfamily d.20.1: UBC-like [54495] (5 families) (S)
  5. Family d.20.1.1: UBC-related [54496] (7 proteins)

Proteins:

  1. Hypothetical protein Tgtwinscan_2721, E2 domain [143066] (1 species)
  2. Putative ubiquitin-conjugating enzyme, E2 domain [143070] (1 species)
  3. Ubiquitin conjugating enzyme, UBC [54497] (34 species)
    1. Species African clawed frog (Xenopus laevis) [TaxId:8355] [160080] (1 PDB entry)
    2. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [187672] (2 PDB entries)
    3. Species Baker's yeast (Saccharomyces cerevisiae), mms2 [TaxId:4932] [64241] (2 PDB entries)
    4. Species Baker's yeast (Saccharomyces cerevisiae), ubc1 [TaxId:4932] [69685] (3 PDB entries)
      Uniprot P21734
    5. Species Baker's yeast (Saccharomyces cerevisiae), ubc13 [TaxId:4932] [64239] (5 PDB entries)
    6. Species Baker's yeast (Saccharomyces cerevisiae), ubc2 (RAD6) [TaxId:4932] [54499] (1 PDB entry)
    7. Species Baker's yeast (Saccharomyces cerevisiae), ubc4 [TaxId:4932] [54500] (1 PDB entry)
    8. Species Baker's yeast (Saccharomyces cerevisiae), ubc7 [TaxId:4932] [54501] (1 PDB entry)
    9. Species Caenorhabditis elegans, E2 2 [TaxId:6239] [143060] (1 PDB entry)
      Uniprot P35129 1-147
    10. Species Clam (Spisula solidissima), E-2C [TaxId:6584] [54504] (2 PDB entries)
    11. Species Human (Homo sapiens) [TaxId:9606] [385992] (1 PDB entry)
    12. Species Human (Homo sapiens), E2 D3 [TaxId:9606] [143054] (3 PDB entries)
      Uniprot P61077 1-147
    13. Species Human (Homo sapiens), E2 G1 [TaxId:9606] [143056] (1 PDB entry)
      Uniprot P62253 7-131
    14. Species Human (Homo sapiens), E2 H [TaxId:9606] [143055] (2 PDB entries)
      Uniprot P62256 4-155
    15. Species Human (Homo sapiens), E2 J2 [TaxId:9606] [143050] (1 PDB entry)
      Uniprot Q5T7L1 12-168
      ubc6 homologue
    16. Species Human (Homo sapiens), E2 L6 [TaxId:9606] [143052] (1 PDB entry)
      Uniprot O14933 2-151
    17. Species Human (Homo sapiens), E2 M [TaxId:9606] [143058] (3 PDB entries)
      Uniprot P61081 27-183
      the extra N-terminal peptide, bound to the heterodimeric E1 enzyme for NEDD8, can be seen in the PDB entry 1tt5, chains E and F
    18. Species Human (Homo sapiens), E2 S [TaxId:9606] [143048] (1 PDB entry)
      Uniprot Q16763 6-156
    19. Species Human (Homo sapiens), E2 T [TaxId:9606] [143057] (1 PDB entry)
      Uniprot Q9NPD8 1-154
      Hspc150
    20. Species Human (Homo sapiens), E2 U [TaxId:9606] [143053] (1 PDB entry)
      Uniprot Q5VVX9 1-148
    21. Species Human (Homo sapiens), E2 variant 1 [TaxId:9606] [143051] (7 PDB entries)
      Uniprot Q13404 80-221! Uniprot Q13404 82-220
    22. Species Human (Homo sapiens), mms2 [TaxId:9606] [64242] (6 PDB entries)
    23. Species Human (Homo sapiens), ubc13 [TaxId:9606] [64240] (23 PDB entries)
    24. Species Human (Homo sapiens), ubc2b [TaxId:9606] [102840] (4 PDB entries)
      E2-17 kDa
    25. Species Human (Homo sapiens), ubc9 [TaxId:9606] [54503] (29 PDB entries)
      identical sequence in many other species
    26. Species Human (Homo sapiens), ubch10 [TaxId:9606] [64243] (1 PDB entry)
    27. Species Human (Homo sapiens), ubch5b [TaxId:9606] [102841] (31 PDB entries)
      Uniprot P62837
      E2-17 kDa 2
    28. Species Human (Homo sapiens), ubch7 [TaxId:9606] [54502] (2 PDB entries)
    29. Species Human (Homo sapiens), ubch8 [TaxId:9606] [117850] (1 PDB entry)
      Uniprot Q96LR5 54-201
    30. Species Leishmania major [TaxId:5664] [143049] (1 PDB entry)
      Uniprot Q4Q5L3 9-166
      Ubiquitin carrier protein 4, putative
    31. Species Nematode (Caenorhabditis elegans), E2-19 kDa [TaxId:6239] [89862] (1 PDB entry)
    32. Species Nematode (Caenorhabditis elegans), E2-21.5 kDa [TaxId:6239] [102842] (1 PDB entry)
    33. Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [54498] (1 PDB entry)
    34. Species Toxoplasma gondii [TaxId:5811] [143059] (1 PDB entry)
  4. Ubiquitin-conjugating enzyme E2 Q2, C-terminal domain [143068] (1 species)
    this proteins contains the N-terminal RWD domain
  5. Ubiquitin-conjugating enzyme E2-25 kDa, E2 domain [143063] (2 species)
    ubc1 homologue; also contains the C-terminal UBA domain
    1. Species Cow (Bos taurus) [TaxId:9913] [143065] (1 PDB entry)
      Uniprot P61085 1-154
    2. Species Human (Homo sapiens) [TaxId:9606] [143064] (10 PDB entries)
      Uniprot P61086 1-156
  6. Ubiquitin-protein ligase W (E2 W) [143061] (1 species)
    forms segment-swapped dimer
  7. automated matches [190124] (13 species)
    not a true protein
    1. Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [370009] (2 PDB entries)
    2. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [189599] (2 PDB entries)
    3. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [197196] (4 PDB entries)
    4. Species Entamoeba (Entamoeba histolytica) [TaxId:5759] [193761] (1 PDB entry)
    5. Species Fission yeast (Schizosaccharomyces pombe) [TaxId:4896] [189937] (1 PDB entry)
    6. Species Human (Homo sapiens) [TaxId:9606] [186848] (51 PDB entries)
    7. Species Leishmania major [TaxId:5664] [188133] (1 PDB entry)
    8. Species Mouse (Mus musculus) [TaxId:10090] [188773] (1 PDB entry)
    9. Species Nematode (Brugia malayi) [TaxId:6279] [226704] (1 PDB entry)
    10. Species Nematode (Caenorhabditis elegans) [TaxId:6239] [186897] (1 PDB entry)
    11. Species Plasmodium falciparum [TaxId:36329] [187963] (5 PDB entries)
    12. Species Schizosaccharomyces pombe [TaxId:284812] [196618] (2 PDB entries)
    13. Species Zebrafish (Danio rerio) [TaxId:7955] [188346] (1 PDB entry)

More info for Family d.20.1.1: UBC-related

Timeline for Family d.20.1.1: UBC-related: