Lineage for Family d.20.1.1: UBC-related

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2164133Fold d.20: UBC-like [54494] (1 superfamily)
    alpha-beta(4)-alpha(3); core: meander beta-sheet plus one helix 2
  4. 2164134Superfamily d.20.1: UBC-like [54495] (5 families) (S)
  5. 2164135Family d.20.1.1: UBC-related [54496] (7 protein domains)

Protein Domains:

  1. 2164136Hypothetical protein Tgtwinscan_2721, E2 domain [143066] (1 species)
  2. 2164140Putative ubiquitin-conjugating enzyme, E2 domain [143070] (1 species)
  3. 2164143Ubiquitin conjugating enzyme, UBC [54497] (33 species)
    1. 2164144Species African clawed frog (Xenopus laevis) [TaxId:8355] [160080] (1 PDB entry)
    2. 2164146Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [187672] (2 PDB entries)
    3. 2164153Species Baker's yeast (Saccharomyces cerevisiae), mms2 [TaxId:4932] [64241] (2 PDB entries)
    4. 2164156Species Baker's yeast (Saccharomyces cerevisiae), ubc1 [TaxId:4932] [69685] (3 PDB entries)
      Uniprot P21734
    5. 2164161Species Baker's yeast (Saccharomyces cerevisiae), ubc13 [TaxId:4932] [64239] (5 PDB entries)
    6. 2164167Species Baker's yeast (Saccharomyces cerevisiae), ubc2 (RAD6) [TaxId:4932] [54499] (1 PDB entry)
    7. 2164171Species Baker's yeast (Saccharomyces cerevisiae), ubc4 [TaxId:4932] [54500] (1 PDB entry)
    8. 2164173Species Baker's yeast (Saccharomyces cerevisiae), ubc7 [TaxId:4932] [54501] (1 PDB entry)
    9. 2164175Species Caenorhabditis elegans, E2 2 [TaxId:6239] [143060] (1 PDB entry)
      Uniprot P35129 1-147
    10. 2164177Species Clam (Spisula solidissima), E-2C [TaxId:6584] [54504] (2 PDB entries)
    11. 2164182Species Human (Homo sapiens), E2 D3 [TaxId:9606] [143054] (3 PDB entries)
      Uniprot P61077 1-147
    12. 2164186Species Human (Homo sapiens), E2 G1 [TaxId:9606] [143056] (1 PDB entry)
      Uniprot P62253 7-131
    13. 2164188Species Human (Homo sapiens), E2 H [TaxId:9606] [143055] (2 PDB entries)
      Uniprot P62256 4-155
    14. 2164193Species Human (Homo sapiens), E2 J2 [TaxId:9606] [143050] (1 PDB entry)
      Uniprot Q5T7L1 12-168
      ubc6 homologue
    15. 2164196Species Human (Homo sapiens), E2 L6 [TaxId:9606] [143052] (1 PDB entry)
      Uniprot O14933 2-151
    16. 2164198Species Human (Homo sapiens), E2 M [TaxId:9606] [143058] (3 PDB entries)
      Uniprot P61081 27-183
      the extra N-terminal peptide, bound to the heterodimeric E1 enzyme for NEDD8, can be seen in the PDB entry 1tt5, chains E and F
    17. 2164203Species Human (Homo sapiens), E2 S [TaxId:9606] [143048] (1 PDB entry)
      Uniprot Q16763 6-156
    18. 2164205Species Human (Homo sapiens), E2 T [TaxId:9606] [143057] (1 PDB entry)
      Uniprot Q9NPD8 1-154
      Hspc150
    19. 2164207Species Human (Homo sapiens), E2 U [TaxId:9606] [143053] (1 PDB entry)
      Uniprot Q5VVX9 1-148
    20. 2164209Species Human (Homo sapiens), E2 variant 1 [TaxId:9606] [143051] (6 PDB entries)
      Uniprot Q13404 80-221! Uniprot Q13404 82-220
    21. 2164216Species Human (Homo sapiens), mms2 [TaxId:9606] [64242] (6 PDB entries)
    22. 2164233Species Human (Homo sapiens), ubc13 [TaxId:9606] [64240] (7 PDB entries)
    23. 2164243Species Human (Homo sapiens), ubc2b [TaxId:9606] [102840] (4 PDB entries)
      E2-17 kDa
    24. 2164248Species Human (Homo sapiens), ubc9 [TaxId:9606] [54503] (29 PDB entries)
      identical sequence in many other species
    25. 2164276Species Human (Homo sapiens), ubch10 [TaxId:9606] [64243] (1 PDB entry)
    26. 2164279Species Human (Homo sapiens), ubch5b [TaxId:9606] [102841] (18 PDB entries)
      Uniprot P62837
      E2-17 kDa 2
    27. 2164302Species Human (Homo sapiens), ubch7 [TaxId:9606] [54502] (2 PDB entries)
    28. 2164305Species Human (Homo sapiens), ubch8 [TaxId:9606] [117850] (1 PDB entry)
      Uniprot Q96LR5 54-201
    29. 2164309Species Leishmania major [TaxId:5664] [143049] (1 PDB entry)
      Uniprot Q4Q5L3 9-166
      Ubiquitin carrier protein 4, putative
    30. 2164311Species Nematode (Caenorhabditis elegans), E2-19 kDa [TaxId:6239] [89862] (1 PDB entry)
    31. 2164313Species Nematode (Caenorhabditis elegans), E2-21.5 kDa [TaxId:6239] [102842] (1 PDB entry)
    32. 2164317Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [54498] (1 PDB entry)
    33. 2164319Species Toxoplasma gondii [TaxId:5811] [143059] (1 PDB entry)
  4. 2164321Ubiquitin-conjugating enzyme E2 Q2, C-terminal domain [143068] (1 species)
    this proteins contains the N-terminal RWD domain
  5. 2164325Ubiquitin-conjugating enzyme E2-25 kDa, E2 domain [143063] (2 species)
    ubc1 homologue; also contains the C-terminal UBA domain
    1. 2164326Species Cow (Bos taurus) [TaxId:9913] [143065] (1 PDB entry)
      Uniprot P61085 1-154
    2. 2164328Species Human (Homo sapiens) [TaxId:9606] [143064] (7 PDB entries)
      Uniprot P61086 1-156
  6. 2164338Ubiquitin-protein ligase W (E2 W) [143061] (1 species)
    forms segment-swapped dimer
  7. 2164342automated matches [190124] (12 species)
    not a true protein
    1. 2164343Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [189599] (2 PDB entries)
    2. 2164346Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [197196] (4 PDB entries)
    3. 2164350Species Entamoeba (Entamoeba histolytica) [TaxId:5759] [193761] (1 PDB entry)
    4. 2164352Species Fission yeast (Schizosaccharomyces pombe) [TaxId:4896] [189937] (1 PDB entry)
    5. 2164354Species Human (Homo sapiens) [TaxId:9606] [186848] (46 PDB entries)
    6. 2164432Species Leishmania major [TaxId:5664] [188133] (1 PDB entry)
    7. 2164435Species Mouse (Mus musculus) [TaxId:10090] [188773] (1 PDB entry)
    8. 2164438Species Nematode (Brugia malayi) [TaxId:6279] [226704] (1 PDB entry)
    9. 2164440Species Nematode (Caenorhabditis elegans) [TaxId:6239] [186897] (1 PDB entry)
    10. 2164442Species Plasmodium falciparum [TaxId:36329] [187963] (5 PDB entries)
    11. 2164454Species Schizosaccharomyces pombe [TaxId:284812] [196618] (1 PDB entry)
    12. 2164456Species Zebrafish (Danio rerio) [TaxId:7955] [188346] (1 PDB entry)

More info for Family d.20.1.1: UBC-related

Timeline for Family d.20.1.1: UBC-related: