SCOPe 2.08: Protein: Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1)

Lineage for Protein: Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1)

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
Fold c.62: vWA-like [53299] (1 superfamily)
core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest
Superfamily c.62.1: vWA-like [53300] (6 families)
Family c.62.1.1: Integrin A (or I) domain [53301] (12 proteins)
Protein Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1) [53302] (1 species)

Species:

Human (Homo sapiens) [TaxId:9606] [53303] (26 PDB entries)
Uniprot P20701 153-334
1. Domains for 1cqp:
  1. Domain d1cqpa_: 1cqp A: [34127]
    complexed with lovastatin
    complexed with 803, mg
  2. Domain d1cqpb_: 1cqp B: [34128]
    complexed with lovastatin
    complexed with 803, mg
2. Domain for 1dgq:
  - Domain d1dgqa_: 1dgq A: [34131]
3. Domains for 1lfa:
  1. Domain d1lfaa_: 1lfa A: [34122]
    complexed with cl, mn
  2. Domain d1lfab_: 1lfa B: [34123]
    complexed with cl, mn
4. Domain for 1mjn:
  - Domain d1mjna_: 1mjn A: [79210]
    complexed with mg; mutant
5. Domains for 1mq8:
  1. Domain d1mq8b_: 1mq8 B: [79407]
    Other proteins in same PDB: d1mq8a1, d1mq8a2, d1mq8c1, d1mq8c2
    complex with ICAM-1
    complexed with mg, nag
  2. Domain d1mq8d_: 1mq8 D: [79410]
    Other proteins in same PDB: d1mq8a1, d1mq8a2, d1mq8c1, d1mq8c2
    complex with ICAM-1
    complexed with mg, nag
6. Domain for 1mq9:
  - Domain d1mq9a_: 1mq9 A: [79411]
    complexed with mn
7. Domain for 1mqa:
  - Domain d1mqaa1: 1mqa A:128-300 [79412]
    Other proteins in same PDB: d1mqaa2
8. Domains for 1rd4:
  1. Domain d1rd4a_: 1rd4 A: [97304]
    complexed with l08
  2. Domain d1rd4b_: 1rd4 B: [97305]
    complexed with l08
  3. Domain d1rd4c_: 1rd4 C: [97306]
    complexed with l08
  4. Domain d1rd4d_: 1rd4 D: [97307]
    complexed with l08
9. Domain for 1t0p:
  - Domain d1t0pa_: 1t0p A: [161739]
    automated match to d1mqaa_
    complexed with mg, nag
10. Domains for 1xdd:
  1. Domain d1xdda_: 1xdd A: [109567]
    complexed with aay, mg
  2. Domain d1xddb_: 1xdd B: [109568]
    complexed with aay, mg
11. Domains for 1xdg:
  1. Domain d1xdga_: 1xdg A: [109569]
    complexed with ab8, mg
  2. Domain d1xdgb_: 1xdg B: [109570]
    complexed with ab8, mg
12. Domains for 1xuo:
  1. Domain d1xuoa_: 1xuo A: [122336]
    automated match to d1dgqa_
    complexed with la1, mg
  2. Domain d1xuob_: 1xuo B: [122337]
    automated match to d1dgqa_
    complexed with la1, mg
13. Domain for 1zon:
  - Domain d1zona_: 1zon A: [34126]
14. Domains for 1zoo:
  1. Domain d1zooa_: 1zoo A: [34129]
    complexed with cl, mg
  2. Domain d1zoob_: 1zoo B: [34130]
    complexed with cl, mg
15. Domains for 1zop:
  1. Domain d1zopa_: 1zop A: [34124]
    complexed with cl, mn
  2. Domain d1zopb_: 1zop B: [34125]
    complexed with cl, mn
16. Domain for 2ica:
  - Domain d2icaa2: 2ica A:129-306 [137236]
    Other proteins in same PDB: d2icaa3
    automated match to d1lfaa_
    complexed with 2ic
17. Domain for 2o7n:
  - Domain d2o7na2: 2o7n A:129-307 [138929]
    Other proteins in same PDB: d2o7na3
    automated match to d1lfaa_
    complexed with 2o7
18. Domain for 3bn3:
  - Domain d3bn3a_: 3bn3 A: [172715]
    Other proteins in same PDB: d3bn3b1, d3bn3b2
    automated match to d1dgqa_
    complexed with gol, mg, nag
19. Domains for 3bqm:
  1. Domain d3bqmb_: 3bqm B: [155499]
    automated match to d1cqpa_
    complexed with bqm
  2. Domain d3bqmc_: 3bqm C: [155500]
    automated match to d1cqpa_
    complexed with bqm
20. Domains for 3bqn:
  1. Domain d3bqnb_: 3bqn B: [155501]
    automated match to d1cqpa_
    complexed with bqn
  2. Domain d3bqnc_: 3bqn C: [155502]
    automated match to d1cqpa_
    complexed with bqn
21. Domains for 3e2m:
  1. Domain d3e2ma_: 3e2m A: [157989]
    automated match to d1dgqa_
    complexed with e2m
  2. Domain d3e2mb_: 3e2m B: [157990]
    automated match to d1dgqa_
    complexed with e2m
22. Domains for 3eoa:
  1. Domain d3eoai_: 3eoa I: [175114]
    Other proteins in same PDB: d3eoaa1, d3eoaa2, d3eoab_, d3eoah_, d3eoal1, d3eoal2
    automated match to d1lfaa_
  2. Domain d3eoaj_: 3eoa J: [175115]
    Other proteins in same PDB: d3eoaa1, d3eoaa2, d3eoab_, d3eoah_, d3eoal1, d3eoal2
    automated match to d1lfaa_
23. Domains for 3f74:
  1. Domain d3f74a_: 3f74 A: [175535]
    automated match to d1cqpa_
    complexed with gol, mg
  2. Domain d3f74b_: 3f74 B: [175536]
    automated match to d1cqpa_
    complexed with gol, mg
  3. Domain d3f74c_: 3f74 C: [175537]
    automated match to d1cqpa_
    complexed with gol, mg
24. Domains for 3f78:
  1. Domain d3f78a_: 3f78 A: [175539]
    automated match to d1cqpa_
    complexed with gol, icf, mg
  2. Domain d3f78b_: 3f78 B: [175540]
    automated match to d1cqpa_
    complexed with gol, icf, mg
  3. Domain d3f78c_: 3f78 C: [175541]
    automated match to d1cqpa_
    complexed with gol, icf, mg
25. Domain for 3m6f:
  - Domain d3m6fa1: 3m6f A:129-307 [180894]
    Other proteins in same PDB: d3m6fa2
    automated match to d1lfaa_
    complexed with bjz, no3
26. Domain for 4ixd:
  - Domain d4ixda_: 4ixd A: [236416]
    automated match to d1dgqa_
    complexed with 1hv, mg

More info for Protein Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1) from c.62.1.1: Integrin A (or I) domain

Timeline for Protein Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1) from c.62.1.1: Integrin A (or I) domain:

Protein Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1) from c.62.1.1: Integrin A (or I) domain first appeared (with stable ids) in SCOP 1.55
Protein Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1) from c.62.1.1: Integrin A (or I) domain appears in SCOPe 2.07