Lineage for d2icaa2 (2ica A:129-306)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2128912Fold c.62: vWA-like [53299] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest
  4. 2128913Superfamily c.62.1: vWA-like [53300] (6 families) (S)
  5. 2128914Family c.62.1.1: Integrin A (or I) domain [53301] (11 protein domains)
  6. 2128986Protein Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1) [53302] (1 species)
  7. 2128987Species Human (Homo sapiens) [TaxId:9606] [53303] (26 PDB entries)
    Uniprot P20701 153-334
  8. 2128995Domain d2icaa2: 2ica A:129-306 [137236]
    Other proteins in same PDB: d2icaa3
    automated match to d1lfaa_
    complexed with 2ic

Details for d2icaa2

PDB Entry: 2ica (more details), 1.56 Å

PDB Description: CD11a (LFA1) I-domain complexed with BMS-587101 aka 5-[(5S, 9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro [4.4]non-7-yl]methyl]-3-thiophenecarboxylicacid
PDB Compounds: (A:) Integrin alpha-L

SCOPe Domain Sequences for d2icaa2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2icaa2 c.62.1.1 (A:129-306) Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2icaa2:

Click to download the PDB-style file with coordinates for d2icaa2.
(The format of our PDB-style files is described here.)

Timeline for d2icaa2:

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