PDB entry 3m6f

View 3m6f on RCSB PDB site
Description: CD11A I-domain complexed with 6-((5S,9R)-9-(4-CYANOPHENYL)-3-(3,5-DICHLOROPHENYL)-1-METHYL-2,4-DIOXO-1,3,7- TRIAZASPIRO[4.4]NON-7-YL)NICOTINIC ACID
Class: cell adhesion
Keywords: LFA1, INHIBITOR, Alternative splicing, Calcium, Cell adhesion, Disulfide bond, Glycoprotein, Integrin, Magnesium, Membrane, Polymorphism, Receptor, Transmembrane
Deposited on 2010-03-15, released 2010-05-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-04-11, with a file datestamp of 2018-04-06.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Integrin alpha-L
    Species: Homo sapiens [TaxId:9606]
    Gene: ITGAL, CD11A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20701 (4-182)
      • expression tag (3)
    Domains in SCOPe 2.08: d3m6fa1, d3m6fa2
  • Heterogens: BJZ, NO3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3m6fA (A:)
gshmnvdlvflfdgsmslqpdefqkildfmkdvmkklsntsyqfaavqfstsyktefdfs
dyvkrkdpdallkhvkhmllltntfgainyvatevfreelgarpdatkvliiitdgeatd
sgnidaakdiiryiigigkhfqtkesqetlhkfaskpasefvkildtfeklkdlftelqk
kiy

    Sequence, based on observed residues (ATOM records): (download) 
    >3m6fA (A:)
mnvdlvflfdgsmslqpdefqkildfmkdvmkklsntsyqfaavqfstsyktefdfsdyv
krkdpdallkhvkhmllltntfgainyvatevfreelgarpdatkvliiitdgeatdsgn
idaakdiiryiigigkhfqtkesqetlhkfaskpasefvkildtfeklkdlftelqkkiy