Lineage for Protein: Methylenetetrahydrofolate reductase

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2089931Superfamily c.1.23: FAD-linked oxidoreductase [51730] (2 families) (S)
    distinct cofactor-binding mode from both FMN- and NAD(P)-linked TIM-barrel oxidoreductases; families are related by a circular permutation
  5. 2089932Family c.1.23.1: Methylenetetrahydrofolate reductase [51731] (2 protein domains)
    automatically mapped to Pfam PF02219
  6. 2089933Protein Methylenetetrahydrofolate reductase [51732] (2 species)

Species:

  1. 2089934Escherichia coli [TaxId:562] [51733] (7 PDB entries)
    1. Domains for 1b5t:
      1. 2089950Domain d1b5ta_: 1b5t A: [29676]
        complexed with fad, hg
      2. 2089951Domain d1b5tb_: 1b5t B: [29677]
        complexed with fad, hg
      3. 2089952Domain d1b5tc_: 1b5t C: [29678]
        complexed with fad, hg
    2. Domains for 1zp3:
      1. 2089938Domain d1zp3a_: 1zp3 A: [203352]
        automated match to d1b5tb_
        complexed with fad, mpd, so4
      2. 2089939Domain d1zp3b_: 1zp3 B: [203353]
        automated match to d1b5tb_
        complexed with fad, mpd, so4
      3. 2089940Domain d1zp3c_: 1zp3 C: [203354]
        automated match to d1b5tb_
        complexed with fad, mpd, so4
    3. Domains for 1zp4:
      1. 2089935Domain d1zp4a_: 1zp4 A: [203355]
        automated match to d1b5tb_
        complexed with c2f, fad, so4; mutant
      2. 2089936Domain d1zp4b_: 1zp4 B: [203356]
        automated match to d1b5tb_
        complexed with c2f, fad, so4; mutant
      3. 2089937Domain d1zp4c_: 1zp4 C: [203357]
        automated match to d1b5tb_
        complexed with c2f, fad, so4; mutant
    4. Domains for 1zpt:
      1. 2089947Domain d1zpta_: 1zpt A: [203358]
        automated match to d1b5tb_
        complexed with fad, nai, so4
      2. 2089948Domain d1zptb_: 1zpt B: [203359]
        automated match to d1b5tb_
        complexed with fad, nai, so4
      3. 2089949Domain d1zptc_: 1zpt C: [203360]
        automated match to d1b5tb_
        complexed with fad, nai, so4
    5. Domains for 1zrq:
      1. 2089953Domain d1zrqa_: 1zrq A: [203361]
        automated match to d1b5tb_
        complexed with fad, nai, so4
      2. 2089954Domain d1zrqb_: 1zrq B: [203362]
        automated match to d1b5tb_
        complexed with fad, nai, so4
      3. 2089955Domain d1zrqc_: 1zrq C: [203363]
        automated match to d1b5tb_
        complexed with fad, nai, so4
    6. Domains for 2fmn:
      1. 2089941Domain d2fmna_: 2fmn A: [204229]
        automated match to d1b5tb_
        complexed with 4hf, fad; mutant
      2. 2089942Domain d2fmnb_: 2fmn B: [204230]
        automated match to d1b5tb_
        complexed with 4hf, fad; mutant
      3. 2089943Domain d2fmnc_: 2fmn C: [204231]
        automated match to d1b5tb_
        complexed with 4hf, fad; mutant
    7. Domains for 2fmo:
      1. 2089944Domain d2fmoa_: 2fmo A: [204232]
        automated match to d1b5tb_
        complexed with fad, mpd, so4; mutant
      2. 2089945Domain d2fmob_: 2fmo B: [204233]
        automated match to d1b5tb_
        complexed with fad, mpd, so4; mutant
      3. 2089946Domain d2fmoc_: 2fmo C: [204234]
        automated match to d1b5tb_
        complexed with fad, mpd, so4; mutant
  2. 2089956Thermus thermophilus [TaxId:274] [102106] (1 PDB entry)

More info for Protein Methylenetetrahydrofolate reductase from c.1.23.1: Methylenetetrahydrofolate reductase

Timeline for Protein Methylenetetrahydrofolate reductase from c.1.23.1: Methylenetetrahydrofolate reductase: