Lineage for Protein: Interferon-gamma

  1. Root: SCOP 1.71
  2. 530466Class a: All alpha proteins [46456] (226 folds)
  3. 536620Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 536621Superfamily a.26.1: 4-helical cytokines [47266] (3 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 536777Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (8 proteins)
    contains an additional helix in one of the crossover connections
  6. 536796Protein Interferon-gamma [47318] (3 species)
    intertwined dimer

Species:

  1. 536797Cow (Bos taurus) [TaxId:9913] [47319] (3 PDB entries)
    1. Domains for 1d9c:
      1. 536798Domain d1d9ca_: 1d9c A: [16901]
      2. 536799Domain d1d9cb_: 1d9c B: [16902]
    2. Domains for 1d9g:
      1. 536800Domain d1d9ga_: 1d9g A: [16903]
      2. 536801Domain d1d9gb_: 1d9g B: [16904]
    3. Domains for 1rfb:
      1. 536802Domain d1rfba_: 1rfb A: [16905]
      2. 536803Domain d1rfbb_: 1rfb B: [16906]
  2. 536804Human (Homo sapiens) [TaxId:9606] [47320] (4 PDB entries)
    1. Domains for 1eku:
      1. 536815Domain d1ekua1: 1eku A:0-121 [16911]
      2. 536816Domain d1ekua2: 1eku A:123-242 [16912]
      3. 536817Domain d1ekub1: 1eku B:0-121 [16913]
      4. 536818Domain d1ekub2: 1eku B:123-241 [16914]
        biologically active single chain mutant
    2. Domains for 1fg9:
      1. 536809Domain d1fg9a_: 1fg9 A: [16915]
        Other proteins in same PDB: d1fg9c1, d1fg9c2, d1fg9d1, d1fg9d2, d1fg9e1, d1fg9e2
      2. 536810Domain d1fg9b_: 1fg9 B: [16916]
        Other proteins in same PDB: d1fg9c1, d1fg9c2, d1fg9d1, d1fg9d2, d1fg9e1, d1fg9e2
    3. Domains for 1fyh:
      1. 536805Domain d1fyha1: 1fyh A:0-124 [16907]
        Other proteins in same PDB: d1fyhb1, d1fyhb2, d1fyhe1, d1fyhe2
      2. 536806Domain d1fyha2: 1fyh A:201-324 [16908]
        Other proteins in same PDB: d1fyhb1, d1fyhb2, d1fyhe1, d1fyhe2
      3. 536807Domain d1fyhd1: 1fyh D:0-124 [16909]
        Other proteins in same PDB: d1fyhb1, d1fyhb2, d1fyhe1, d1fyhe2
      4. 536808Domain d1fyhd2: 1fyh D:201-324 [16910]
        Other proteins in same PDB: d1fyhb1, d1fyhb2, d1fyhe1, d1fyhe2
        a single-chain variant
        complexed with cl
    4. Domains for 1hig:
      1. 536811Domain d1higa_: 1hig A: [16917]
      2. 536812Domain d1higb_: 1hig B: [16918]
      3. 536813Domain d1higc_: 1hig C: [16919]
      4. 536814Domain d1higd_: 1hig D: [16920]
        CA-atoms only
  3. 536819Rabbit (Oryctolagus cuniculus) [TaxId:9986] [47321] (1 PDB entry)

More info for Protein Interferon-gamma from a.26.1.3: Interferons/interleukin-10 (IL-10)

Timeline for Protein Interferon-gamma from a.26.1.3: Interferons/interleukin-10 (IL-10):