PDB entry 2q9q

View 2q9q on RCSB PDB site
Description: The crystal structure of full length human GINS complex
Class: replication
Keywords: elongated spindle, helix bundle, REPLICATION
Deposited on 2007-06-13, released 2007-08-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.36 Å
R-factor: 0.21
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA replication complex GINS protein PSF2
    Species: Homo sapiens [TaxId:9606]
    Gene: GINS2, PSF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2q9qa1, d2q9qa2
  • Chain 'B':
    Compound: GINS complex subunit 4
    Species: Homo sapiens [TaxId:9606]
    Gene: GINS4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2q9qb1, d2q9qb2
  • Chain 'C':
    Compound: DNA replication complex GINS protein PSF1
    Species: Homo sapiens [TaxId:9606]
    Gene: GINS1, KIAA0186, PSF1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14691 (0-End)
      • variant (96)
    Domains in SCOPe 2.08: d2q9qc_
  • Chain 'D':
    Compound: GINS complex subunit 3
    Species: Homo sapiens [TaxId:9606]
    Gene: GINS3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2q9qd1, d2q9qd2
  • Chain 'E':
    Compound: DNA replication complex GINS protein PSF2
    Species: Homo sapiens [TaxId:9606]
    Gene: GINS2, PSF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2q9qe1, d2q9qe2
  • Chain 'F':
    Compound: GINS complex subunit 4
    Species: Homo sapiens [TaxId:9606]
    Gene: GINS4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2q9qf1, d2q9qf2
  • Chain 'G':
    Compound: DNA replication complex GINS protein PSF1
    Species: Homo sapiens [TaxId:9606]
    Gene: GINS1, KIAA0186, PSF1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14691 (0-End)
      • variant (96)
    Domains in SCOPe 2.08: d2q9qg_
  • Chain 'H':
    Compound: GINS complex subunit 3
    Species: Homo sapiens [TaxId:9606]
    Gene: GINS3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2q9qh1, d2q9qh2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2q9qA (A:)
gplgsnmdaaeveflaekelvtiipnfsldkiyliggdlgpfnpglpvevplwlainlkq
rqkcrllppewmdveklekmrdherkeetftpmpspyymeltklllnhasdnipkadeir
tlvkdmwdtriaklrvsadsfvrqqeahakldnltlmeintsgtfltqalnhmyklrtnl
qplestqsqdf

    Sequence, based on observed residues (ATOM records): (download) 
    >2q9qA (A:)
mdaaeveflaekelvtiipnfsldkiyliggdlgpfnpglpvevplwlainlkqrqkcrl
lppewmdveklekmrdherkeetftpmpspyymeltklllnhasdnipkadeirtlvkdm
wdtriaklrvsadsfvrqqeahakldnltlmeintsgtfltqalnhmyklrtnlq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2q9qB (B:)
mteevdflgqdsdggseevvltpaelierleqawmnekfapelleskpeivecvmeqleh
meenlrrakredlkvsihqmemeriryvlssylrcrlmkiekffphvlekektrpegeps
slspeelafarefmantesylknvalkhmppnlqkvdlfravpkpdldsyvflrvrerqe
nilvepdtdeqrdyvidlekgsqhliryktiaplvasgavqli

    Sequence, based on observed residues (ATOM records): (download) 
    >2q9qB (B:)
ltpaelierleqawmnekfapelleskpeivecvmeqlehmeenldlkvsihqmemerir
yvlssylrcrlmkiekffphvlekektrpegepsslspeelafarefmantesylknval
khmppnlqkvdlfravpkpdldsyvflrvrerqenilvepdtdeqrdyvidlekgsqhli
ryktiaplvasgavql

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2q9qC (C:)
mfcekamelirelhrapegqlpafnedglrqvleemkalyeqnqsdvneaksggrsdlip
tikfrhcsllrnrrctvaylydrllriralrweygsilpnalrfhmaaeemewfnnykrs
latymrslggdeglditqdmkppkslyievrclkdygefevddgtsvllkknsqhflprw
kceqlirqgvlehils

    Sequence, based on observed residues (ATOM records): (download) 
    >2q9qC (C:)
mfcekamelirelhrapegqlpafnedglrqvleemkalyeqnqsdvneaksggrsdlip
tikfrhcsllrnrrctvaylydrllriralrweygsilpnalrfhmaaeemewfnnykrs
latymrslggdeglditqdmkppks

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2q9qD (D:)
gpgggseayfrvesgalgpeenflslddilmsheklpvrtetamprlgafflersagaet
dnavpqgsklelplwlakglfdnkrrilsvelpkiyqegwrtvfsadpnvvdlhkmgphf
ygfgsqllhfdspenadisqsllqtfigrfrrimdssqnaynedtsalvarldemerglf
qtgqkglndfqcwekgqasqitasnlvqnykkrkftdmed

    Sequence, based on observed residues (ATOM records): (download) 
    >2q9qD (D:)
seayfrvesgalgpeenflslddilmsheklpvrtetamprlgaffaetdnavpqgskle
lplwlakglfdnkrrilsvelpkiyqegwrtvfsadpnvvdlhkmgphfygfgsqllhfd
spenadisqsllqtfigrfrrimdssqnaynedtsalvarldemerglfqtgqkglndfq
cwekgq

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2q9qE (E:)
gplgsnmdaaeveflaekelvtiipnfsldkiyliggdlgpfnpglpvevplwlainlkq
rqkcrllppewmdveklekmrdherkeetftpmpspyymeltklllnhasdnipkadeir
tlvkdmwdtriaklrvsadsfvrqqeahakldnltlmeintsgtfltqalnhmyklrtnl
qplestqsqdf

    Sequence, based on observed residues (ATOM records): (download) 
    >2q9qE (E:)
mdaaeveflaekelvtiipnfsldkiyliggdlgpfnpglpvevplwlainlkqrqkcrl
lppewmdveklekmrdherkeetftpmpspyymeltklllnhasdnipkadeirtlvkdm
wdtriaklrvsadsfvrqqeahakldnltlmeintsgtfltqalnhmyklrtnlq

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2q9qF (F:)
mteevdflgqdsdggseevvltpaelierleqawmnekfapelleskpeivecvmeqleh
meenlrrakredlkvsihqmemeriryvlssylrcrlmkiekffphvlekektrpegeps
slspeelafarefmantesylknvalkhmppnlqkvdlfravpkpdldsyvflrvrerqe
nilvepdtdeqrdyvidlekgsqhliryktiaplvasgavqli

    Sequence, based on observed residues (ATOM records): (download) 
    >2q9qF (F:)
ltpaelierleqawmnekfapelleskpeivecvmeqlehmeenldlkvsihqmemerir
yvlssylrcrlmkiekffphvlekektrpegepsslspeelafarefmantesylknval
khmppnlqkvdlfravpkpdldsyvflrvrerqenilvepdtdeqrdyvidlekgsqhli
ryktiaplvasgavql

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2q9qG (G:)
mfcekamelirelhrapegqlpafnedglrqvleemkalyeqnqsdvneaksggrsdlip
tikfrhcsllrnrrctvaylydrllriralrweygsilpnalrfhmaaeemewfnnykrs
latymrslggdeglditqdmkppkslyievrclkdygefevddgtsvllkknsqhflprw
kceqlirqgvlehils

    Sequence, based on observed residues (ATOM records): (download) 
    >2q9qG (G:)
mfcekamelirelhrapegqlpafnedglrqvleemkalyeqnqsdvneaksggrsdlip
tikfrhcsllrnrrctvaylydrllriralrweygsilpnalrfhmaaeemewfnnykrs
latymrslggdeglditqdmkppks

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2q9qH (H:)
gpgggseayfrvesgalgpeenflslddilmsheklpvrtetamprlgafflersagaet
dnavpqgsklelplwlakglfdnkrrilsvelpkiyqegwrtvfsadpnvvdlhkmgphf
ygfgsqllhfdspenadisqsllqtfigrfrrimdssqnaynedtsalvarldemerglf
qtgqkglndfqcwekgqasqitasnlvqnykkrkftdmed

    Sequence, based on observed residues (ATOM records): (download) 
    >2q9qH (H:)
seayfrvesgalgpeenflslddilmsheklpvrtetamprlgaffaetdnavpqgskle
lplwlakglfdnkrrilsvelpkiyqegwrtvfsadpnvvdlhkmgphfygfgsqllhfd
spenadisqsllqtfigrfrrimdssqnaynedtsalvarldemerglfqtgqkglndfq
cwekgq