Lineage for Protein: GDP-mannose 6-dehydrogenase, middle domain

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2334421Fold a.100: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1 superfamily)
    multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry
  4. 2334422Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like [48179] (13 families) (S)
    N-terminal domain is Rossmann-fold with a family-specific C-terminal extension
  5. 2334531Family a.100.1.4: UDP-glucose/GDP-mannose dehydrogenase dimerisation domain [48191] (2 proteins)
    automatically mapped to Pfam PF00984
  6. 2334532Protein GDP-mannose 6-dehydrogenase, middle domain [89103] (1 species)
    forms segment-swapped dimer, unlike the homologous UDPGDH domain

Species:

More info for Protein GDP-mannose 6-dehydrogenase, middle domain from a.100.1.4: UDP-glucose/GDP-mannose dehydrogenase dimerisation domain

Timeline for Protein GDP-mannose 6-dehydrogenase, middle domain from a.100.1.4: UDP-glucose/GDP-mannose dehydrogenase dimerisation domain:

  • Protein GDP-mannose 6-dehydrogenase, middle domain from a.100.1.4: UDP-glucose/GDP-mannose dehydrogenase dimerisation domain first appeared in SCOP 1.65
  • Protein GDP-mannose 6-dehydrogenase, middle domain from a.100.1.4: UDP-glucose/GDP-mannose dehydrogenase dimerisation domain appears in SCOPe 2.06
  • Protein GDP-mannose 6-dehydrogenase, middle domain from a.100.1.4: UDP-glucose/GDP-mannose dehydrogenase dimerisation domain appears in the current release, SCOPe 2.08