SCOPe 2.08: Protein: Insulin receptor

Lineage for Protein: Insulin receptor

Root: SCOPe 2.08
Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
shares functional and structural similarities with the ATP-grasp fold and PIPK
Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
members organized in the groups and subfamiles specified by the comments
Protein Insulin receptor [56162] (1 species)
PTK group; InsR subfamily; membrane spanning protein tyrosine kinase

Species:

Human (Homo sapiens) [TaxId:9606] [56163] (18 PDB entries)
1. Domain for 1gag:
  - Domain d1gaga_: 1gag A: [41704]
    complexed with 112, mg
2. Domain for 1i44:
  - Domain d1i44a_: 1i44 A: [61664]
    complexed with acp, mg; mutant
3. Domain for 1ir3:
  - Domain d1ir3a_: 1ir3 A: [41702]
    complexed with anp, mg
4. Domain for 1irk:
  - Domain d1irka_: 1irk A: [41703]
    complexed with emc
5. Domain for 1p14:
  - Domain d1p14a_: 1p14 A: [87660]
    mutant
6. Domains for 1rqq:
  1. Domain d1rqqa_: 1rqq A: [97760]
    Other proteins in same PDB: d1rqqc_, d1rqqd_
    complexed with adaptor protein Aps
    complexed with 112, mn
  2. Domain d1rqqb_: 1rqq B: [97761]
    Other proteins in same PDB: d1rqqc_, d1rqqd_
    complexed with adaptor protein Aps
    complexed with 112, mn
7. Domain for 2auh:
  - Domain d2auha1: 2auh A:987-1283 [127329]
    automatically matched to d1rqqa_
    complexed with ca
8. Domains for 2b4s:
  1. Domain d2b4sb_: 2b4s B: [127854]
    Other proteins in same PDB: d2b4sa_, d2b4sc_
    automated match to d1p14a_
    complexed with so4
  2. Domain d2b4sd_: 2b4s D: [127855]
    Other proteins in same PDB: d2b4sa_, d2b4sc_
    automated match to d1p14a_
    complexed with so4
9. Domain for 2z8c:
  - Domain d2z8ca1: 2z8c A:984-1283 [154208]
    automatically matched to d1gaga_
    complexed with s91
10. Domain for 3bu3:
  - Domain d3bu3a_: 3bu3 A: [155590]
    automated match to d1p14a_
11. Domain for 3bu5:
  - Domain d3bu5a_: 3bu5 A: [155591]
    automated match to d1p14a_
    complexed with atp, mg
12. Domain for 3bu6:
  - Domain d3bu6a_: 3bu6 A: [155592]
    automated match to d1p14a_
13. Domain for 3ekk:
  - Domain d3ekka_: 3ekk A: [175017]
    automated match to d1p14a_
    complexed with gs2
14. Domain for 3ekn:
  - Domain d3ekna_: 3ekn A: [175018]
    automated match to d1p14a_
    complexed with gs3
15. Domains for 3eta:
  1. Domain d3etaa_: 3eta A: [175212]
    automated match to d1gaga_
    complexed with 351
  2. Domain d3etab_: 3eta B: [175213]
    automated match to d1gaga_
    complexed with 351
16. Domains for 4ibm:
  1. Domain d4ibma_: 4ibm A: [223092]
    automated match to d3ekka_
    complexed with ir1
  2. Domain d4ibmb_: 4ibm B: [223093]
    automated match to d3ekka_
    complexed with ir1
17. Domain for 4xlv:
  - Domain d4xlva_: 4xlv A: [270870]
    automated match to d1p4ob_
    complexed with acp, mg
18. Domain for 5hhw:
  - Domain d5hhwa_: 5hhw A: [315394]
    automated match to d1p14a_
    complexed with 60o, edo

More info for Protein Insulin receptor from d.144.1.7: Protein kinases, catalytic subunit

Timeline for Protein Insulin receptor from d.144.1.7: Protein kinases, catalytic subunit:

Protein Insulin receptor from d.144.1.7: Protein kinases, catalytic subunit first appeared (with stable ids) in SCOP 1.55, called Protein Insulin receptor from d.144.1.2: Tyrosine kinase
Protein Insulin receptor from d.144.1.7: Protein kinases, catalytic subunit appears in SCOPe 2.07