SCOPe 2.08: Domain d4ibma_: 4ibm A:

Lineage for d4ibma_ (4ibm A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Insulin receptor [56162] (1 species)
   PTK group; InsR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56163] (18 PDB entries)

8. Domain d4ibma_: 4ibm A: [223092]
   automated match to d3ekka_
   complexed with ir1

Details for d4ibma_

PDB Entry: 4ibm, 1.8 Å

PDB Description: crystal structure of insulin receptor kinase domain in complex with an inhibitor irfin-1

PDB Compounds: (A:) Insulin receptor

SCOPe Domain Sequences for d4ibma_:

Sequence; same for both SEQRES and ATOM records:

>d4ibma_ d.144.1.7 (A:) Insulin receptor {Human (Homo sapiens) [TaxId: 9606]}
svyvpdewevsrekitllrelgqgsfgmvyegnardiikgeaetrvavktvnesaslrer
ieflneasvmkgftchhvvrllgvvskgqptlvvmelmahgdlksylrslrpeaennpgr
ppptlqemiqmaaeiadgmaylnakkfvhrdlaarncmvahdftvkigdfgmtrdiyetd
yyrkggkgllpvrwmapeslkdgvfttssdmwsfgvvlweitslaeqpyqglsneqvlkf
vmdggyldqpdncpervtdlmrmcwqfnpnmrptfleivnllkddlhpsfpevsffhsee
n

Timeline for d4ibma_:

• d4ibma_ first appeared in SCOPe 2.03
  
• d4ibma_ appears in SCOPe 2.07