Lineage for Family a.39.1.5: Calmodulin-like

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2710066Fold a.39: EF Hand-like [47472] (4 superfamilies)
    core: 4 helices; array of 2 hairpins, opened
  4. 2710067Superfamily a.39.1: EF-hand [47473] (12 families) (S)
    Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
  5. 2710548Family a.39.1.5: Calmodulin-like [47502] (24 proteins)
    Duplication: made with two pairs of EF-hands

Proteins:

  1. 2710549Calcineurin B-like protein 2 [101182] (1 species)
  2. 2710553Calcineurin regulatory subunit (B-chain) [47530] (3 species)
    1. 2710554Species Cow (Bos taurus) [TaxId:9913] [47531] (1 PDB entry)
    2. 2710556Species Human (Homo sapiens) [TaxId:9606] [47532] (11 PDB entries)
    3. 2710570Species Mouse (Mus musculus) [TaxId:10090] [272883] (1 PDB entry)
  3. 2710572Calcium vector protein [47514] (1 species)
  4. 2710578Calcium- and integrin-binding protein, CIB [47541] (1 species)
  5. 2710584Calcium-dependent protein kinase sk5 CLD [109821] (1 species)
  6. 2710588Calcium-regulated photoprotein [47512] (4 species)
    structurally most similar to sarcoplasmic calcium-binding protein
    1. 2710589Species Hydrozoa (Obelia geniculata), obelin [TaxId:185004] [63542] (1 PDB entry)
    2. 2710591Species Hydrozoa (Obelia longissima), obelin [TaxId:32570] [63541] (8 PDB entries)
      Uniprot Q27709
    3. 2710600Species Jellyfish (Aequorea aequorea), aequorin [TaxId:168712] [47513] (1 PDB entry)
    4. 2710603Species Jellyfish (Aequorea victoria), aequorin 1 [TaxId:6100] [116901] (1 PDB entry)
      Uniprot P07164 16-196
  7. 2710605Calerythrin [101179] (1 species)
    structurally most similar to sarcoplasmic calcium-binding protein
  8. 2710608Calmodulin [47516] (13 species)
    1. 2710609Species African clawed frog (Xenopus laevis) [TaxId:8355] [47521] (19 PDB entries)
    2. 2710634Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [89052] (4 PDB entries)
    3. 2710639Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [368931] (2 PDB entries)
    4. 2710643Species Chicken (Gallus gallus) [TaxId:9031] [47520] (10 PDB entries)
      mutant with a two residue deletion in the central helix
    5. 2710656Species Ciliate (Paramecium tetraurelia) [TaxId:5888] [47523] (7 PDB entries)
      Uniprot Q42478
    6. 2710665Species Cow (Bos taurus) [TaxId:9913] [47518] (16 PDB entries)
      Uniprot P62157
    7. 2710683Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [47522] (13 PDB entries)
    8. 2710701Species Human (Homo sapiens) [TaxId:9606] [47517] (123 PDB entries)
      Uniprot P02593
    9. 2710935Species Mouse (Mus musculus) [TaxId:10090] [224847] (3 PDB entries)
    10. 2710951Species Nematode (Caenorhabditis elegans) [TaxId:6239] [89051] (1 PDB entry)
    11. 2710953Species Norway rat (Rattus norvegicus) [TaxId:10116] [158477] (19 PDB entries)
    12. 2710989Species Potato (Solanum tuberosum) [TaxId:4113] [109820] (1 PDB entry)
    13. Species Rat (Rattus rattus) [TaxId:10117] [47519] (1 PDB entry)
      Uniprot P62161
  9. 2710993Calmodulin-related protein NB-1 (CLP) [74721] (1 species)
  10. 2710996Calmodulin-related protein T21P5.17 [109823] (1 species)
  11. 2710999Caltractin (centrin 2) [89053] (2 species)
    1. 2711000Species Green alga (Chlamydomonas reinhardtii) [TaxId:3055] [89055] (1 PDB entry)
    2. Species Human (Homo sapiens) [TaxId:9606] [89054] (1 PDB entry)
  12. 2711004Cdc4p [63543] (1 species)
  13. 2711007EHCABP [69021] (1 species)
  14. 2711013Frequenin (neuronal calcium sensor 1) [47535] (3 species)
    1. 2711014Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [47536] (2 PDB entries)
    2. 2711017Species Human (Homo sapiens) [TaxId:9606] [63545] (4 PDB entries)
    3. 2711027Species Norway rat (Rattus norvegicus) [TaxId:10116] [228901] (2 PDB entries)
  15. 2711032Guanylate cyclase activating protein 2, GCAP-2 [47537] (1 species)
  16. 2711035Kchip1, Kv4 potassium channel-interacting protein [101184] (2 species)
    1. 2711036Species Human (Homo sapiens) [TaxId:9606] [116902] (1 PDB entry)
      Uniprot Q9NZI2
    2. 2711038Species Norway rat (Rattus norvegicus) [TaxId:10116] [101185] (1 PDB entry)
  17. 2711040Myosin Essential Chain [47524] (3 species)
    1. 2711041Species Bay scallop (Aequipecten irradians) [TaxId:31199] [47525] (13 PDB entries)
      Uniprot P13543
    2. 2711056Species Chicken (Gallus gallus) [TaxId:9031] [47526] (4 PDB entries)
    3. 2711068Species Human (Homo sapiens) [TaxId:9606] [101181] (1 PDB entry)
  18. 2711070Myosin Light Chain Mlc1p [81756] (1 species)
    light chain of class V myosin
  19. 2711076Myosin Regulatory Chain [47527] (2 species)
    1. 2711077Species Bay scallop (Aequipecten irradians) [TaxId:31199] [47528] (15 PDB entries)
      Uniprot P07291
    2. 2711094Species Chicken (Gallus gallus) [TaxId:9031] [47529] (1 PDB entry)
  20. 2711096Neurocalcin [47539] (1 species)
  21. 2711100Recoverin [47533] (1 species)
    Calcium-myristoyl switch; only one EF-hand is functional
  22. 2711116Sarcoplasmic calcium-binding protein [47509] (2 species)
    1. 2711117Species Amphioxus (Branchiostoma lanceolatum) [TaxId:7740] [47511] (1 PDB entry)
    2. 2711119Species Sandworm (Nereis diversicolor) [TaxId:126592] [47510] (2 PDB entries)
      Uniprot P04571
  23. 2711123Troponin C [47503] (6 species)
    1. 2711124Species Chicken (Gallus gallus) [TaxId:9031] [47504] (28 PDB entries)
      Uniprot P09860
    2. 2711156Species Chicken (Gallus gallus), cardiac isoform [TaxId:9031] [47507] (1 PDB entry)
    3. 2711158Species Human (Homo sapiens), cardiac isoform [TaxId:9606] [47508] (28 PDB entries)
    4. 2711192Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [47506] (4 PDB entries)
    5. 2711197Species Rainbow trout (Oncorhynchus mykiss) [TaxId:8022] [109819] (2 PDB entries)
      Uniprot Q7ZZB9 1-89
    6. 2711200Species Turkey (Meleagris gallopavo) [TaxId:9103] [47505] (2 PDB entries)
  24. 2711203automated matches [190064] (21 species)
    not a true protein
    1. 2711204Species African clawed frog (Xenopus laevis) [TaxId:8355] [225045] (1 PDB entry)
    2. 2711206Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [188855] (3 PDB entries)
    3. 2711214Species Bay scallop (Argopecten irradians) [TaxId:31199] [189156] (2 PDB entries)
    4. 2711217Species Chicken (Gallus gallus) [TaxId:9031] [187205] (3 PDB entries)
    5. 2711221Species Cow (Bos taurus) [TaxId:9913] [228970] (3 PDB entries)
    6. 2711225Species Entamoeba histolytica [TaxId:294381] [225835] (3 PDB entries)
    7. 2711232Species Entamoeba histolytica [TaxId:885319] [342565] (1 PDB entry)
    8. 2711239Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [258881] (6 PDB entries)
    9. 2711250Species Human (Homo sapiens) [TaxId:9606] [186813] (11 PDB entries)
    10. 2711269Species Jellyfish (Aequorea victoria) [TaxId:6100] [186782] (7 PDB entries)
    11. 2711326Species Kluyveromyces lactis [TaxId:284590] [195890] (1 PDB entry)
    12. 2711331Species Mitrocoma cellularia [TaxId:31874] [261220] (1 PDB entry)
    13. 2711334Species Mouse (Mus musculus) [TaxId:10090] [187204] (1 PDB entry)
    14. 2711337Species Norway rat (Rattus norvegicus) [TaxId:10116] [355456] (1 PDB entry)
    15. 2711339Species Obelia longissima [TaxId:32570] [237068] (4 PDB entries)
    16. 2711345Species Opsanus tau [TaxId:8068] [255491] (1 PDB entry)
    17. 2711347Species Placopecten magellanicus [TaxId:6577] [189594] (3 PDB entries)
    18. 2711360Species Scherffelia dubia [TaxId:3190] [189616] (1 PDB entry)
    19. 2711363Species Soybean (Glycine max) [TaxId:3847] [255584] (3 PDB entries)
    20. 2711367Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [194524] (2 PDB entries)
    21. 2711371Species Todarodes pacificus [TaxId:6637] [189006] (1 PDB entry)

More info for Family a.39.1.5: Calmodulin-like

Timeline for Family a.39.1.5: Calmodulin-like: