Lineage for Family a.39.1.5: Calmodulin-like

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1994319Fold a.39: EF Hand-like [47472] (4 superfamilies)
    core: 4 helices; array of 2 hairpins, opened
  4. 1994320Superfamily a.39.1: EF-hand [47473] (12 families) (S)
    Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
  5. 1994753Family a.39.1.5: Calmodulin-like [47502] (24 protein domains)
    Duplication: made with two pairs of EF-hands

Protein Domains:

  1. 1994754Calcineurin B-like protein 2 [101182] (1 species)
  2. 1994758Calcineurin regulatory subunit (B-chain) [47530] (3 species)
    1. 1994759Species Cow (Bos taurus) [TaxId:9913] [47531] (1 PDB entry)
    2. 1994761Species Human (Homo sapiens) [TaxId:9606] [47532] (8 PDB entries)
    3. 1994772Species Mouse (Mus musculus) [TaxId:10090] [272883] (1 PDB entry)
  3. 1994774Calcium vector protein [47514] (1 species)
  4. 1994780Calcium- and integrin-binding protein, CIB [47541] (1 species)
  5. 1994786Calcium-dependent protein kinase sk5 CLD [109821] (1 species)
  6. 1994790Calcium-regulated photoprotein [47512] (4 species)
    structurally most similar to sarcoplasmic calcium-binding protein
    1. 1994791Species Hydrozoa (Obelia geniculata), obelin [TaxId:185004] [63542] (1 PDB entry)
    2. 1994793Species Hydrozoa (Obelia longissima), obelin [TaxId:32570] [63541] (8 PDB entries)
      Uniprot Q27709
    3. 1994802Species Jellyfish (Aequorea aequorea), aequorin [TaxId:168712] [47513] (1 PDB entry)
    4. 1994805Species Jellyfish (Aequorea victoria), aequorin 1 [TaxId:6100] [116901] (1 PDB entry)
      Uniprot P07164 16-196
  7. 1994807Calerythrin [101179] (1 species)
    structurally most similar to sarcoplasmic calcium-binding protein
  8. 1994810Calmodulin [47516] (12 species)
    1. 1994811Species African clawed frog (Xenopus laevis) [TaxId:8355] [47521] (19 PDB entries)
    2. 1994831Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [89052] (4 PDB entries)
    3. 1994836Species Chicken (Gallus gallus) [TaxId:9031] [47520] (10 PDB entries)
      mutant with a two residue deletion in the central helix
    4. 1994848Species Ciliate (Paramecium tetraurelia) [TaxId:5888] [47523] (7 PDB entries)
      Uniprot Q42478
    5. 1994857Species Cow (Bos taurus) [TaxId:9913] [47518] (16 PDB entries)
      Uniprot P62157
    6. 1994875Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [47522] (13 PDB entries)
    7. 1994893Species Human (Homo sapiens) [TaxId:9606] [47517] (86 PDB entries)
      Uniprot P02593
    8. 1995051Species Mouse (Mus musculus) [TaxId:10090] [224847] (3 PDB entries)
    9. 1995066Species Nematode (Caenorhabditis elegans) [TaxId:6239] [89051] (1 PDB entry)
    10. 1995068Species Norway rat (Rattus norvegicus) [TaxId:10116] [158477] (17 PDB entries)
    11. 1995102Species Potato (Solanum tuberosum) [TaxId:4113] [109820] (1 PDB entry)
    12. Species Rat (Rattus rattus) [TaxId:10117] [47519] (1 PDB entry)
      Uniprot P62161
  9. 1995106Calmodulin-related protein NB-1 (CLP) [74721] (1 species)
  10. 1995109Calmodulin-related protein T21P5.17 [109823] (1 species)
  11. 1995112Caltractin (centrin 2) [89053] (2 species)
    1. 1995113Species Green alga (Chlamydomonas reinhardtii) [TaxId:3055] [89055] (1 PDB entry)
    2. Species Human (Homo sapiens) [TaxId:9606] [89054] (1 PDB entry)
  12. 1995117Cdc4p [63543] (1 species)
  13. 1995120EHCABP [69021] (1 species)
  14. 1995126Frequenin (neuronal calcium sensor 1) [47535] (3 species)
    1. 1995127Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [47536] (2 PDB entries)
    2. 1995130Species Human (Homo sapiens) [TaxId:9606] [63545] (2 PDB entries)
    3. 1995137Species Norway rat (Rattus norvegicus) [TaxId:10116] [228901] (2 PDB entries)
  15. 1995142Guanylate cyclase activating protein 2, GCAP-2 [47537] (1 species)
  16. 1995145Kchip1, Kv4 potassium channel-interacting protein [101184] (2 species)
    1. 1995146Species Human (Homo sapiens) [TaxId:9606] [116902] (1 PDB entry)
      Uniprot Q9NZI2
    2. 1995148Species Norway rat (Rattus norvegicus) [TaxId:10116] [101185] (1 PDB entry)
  17. 1995150Myosin Essential Chain [47524] (3 species)
    1. 1995151Species Bay scallop (Aequipecten irradians) [TaxId:31199] [47525] (13 PDB entries)
      Uniprot P13543
    2. 1995166Species Chicken (Gallus gallus) [TaxId:9031] [47526] (4 PDB entries)
    3. 1995178Species Human (Homo sapiens) [TaxId:9606] [101181] (1 PDB entry)
  18. 1995180Myosin Light Chain Mlc1p [81756] (1 species)
    light chain of class V myosin
  19. 1995186Myosin Regulatory Chain [47527] (2 species)
    1. 1995187Species Bay scallop (Aequipecten irradians) [TaxId:31199] [47528] (15 PDB entries)
      Uniprot P07291
    2. 1995204Species Chicken (Gallus gallus) [TaxId:9031] [47529] (1 PDB entry)
  20. 1995206Neurocalcin [47539] (1 species)
  21. 1995210Recoverin [47533] (1 species)
    Calcium-myristoyl switch; only one EF-hand is functional
  22. 1995226Sarcoplasmic calcium-binding protein [47509] (2 species)
    1. 1995227Species Amphioxus (Branchiostoma lanceolatum) [TaxId:7740] [47511] (1 PDB entry)
    2. 1995229Species Sandworm (Nereis diversicolor) [TaxId:126592] [47510] (2 PDB entries)
      Uniprot P04571
  23. 1995233Troponin C [47503] (6 species)
    1. 1995234Species Chicken (Gallus gallus) [TaxId:9031] [47504] (28 PDB entries)
      Uniprot P09860
    2. 1995266Species Chicken (Gallus gallus), cardiac isoform [TaxId:9031] [47507] (1 PDB entry)
    3. 1995268Species Human (Homo sapiens), cardiac isoform [TaxId:9606] [47508] (17 PDB entries)
    4. 1995290Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [47506] (4 PDB entries)
    5. 1995295Species Rainbow trout (Oncorhynchus mykiss) [TaxId:8022] [109819] (2 PDB entries)
      Uniprot Q7ZZB9 1-89
    6. 1995298Species Turkey (Meleagris gallopavo) [TaxId:9103] [47505] (2 PDB entries)
  24. 1995301automated matches [190064] (20 species)
    not a true protein
    1. 1995302Species African clawed frog (Xenopus laevis) [TaxId:8355] [225045] (4 PDB entries)
    2. 1995307Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [188855] (3 PDB entries)
    3. 1995315Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [255436] (1 PDB entry)
    4. 1995317Species Bay scallop (Argopecten irradians) [TaxId:31199] [189156] (2 PDB entries)
    5. 1995320Species Chicken (Gallus gallus) [TaxId:9031] [187205] (3 PDB entries)
    6. 1995324Species Cow (Bos taurus) [TaxId:9913] [228970] (3 PDB entries)
    7. 1995328Species Entamoeba histolytica [TaxId:294381] [225835] (3 PDB entries)
    8. 1995335Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [258881] (5 PDB entries)
    9. 1995342Species Human (Homo sapiens) [TaxId:9606] [186813] (24 PDB entries)
    10. 1995373Species Jellyfish (Aequorea victoria) [TaxId:6100] [186782] (4 PDB entries)
    11. 1995382Species Kluyveromyces lactis [TaxId:284590] [195890] (1 PDB entry)
    12. 1995387Species Mitrocoma cellularia [TaxId:31874] [261220] (1 PDB entry)
    13. 1995390Species Mouse (Mus musculus) [TaxId:10090] [187204] (1 PDB entry)
    14. 1995393Species Obelia longissima [TaxId:32570] [237068] (4 PDB entries)
    15. 1995399Species Opsanus tau [TaxId:8068] [255491] (1 PDB entry)
    16. 1995401Species Placopecten magellanicus [TaxId:6577] [189594] (3 PDB entries)
    17. 1995414Species Scherffelia dubia [TaxId:3190] [189616] (1 PDB entry)
    18. 1995417Species Soybean (Glycine max) [TaxId:3847] [255584] (3 PDB entries)
    19. 1995421Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [194524] (2 PDB entries)
    20. 1995424Species Todarodes pacificus [TaxId:6637] [189006] (1 PDB entry)

More info for Family a.39.1.5: Calmodulin-like

Timeline for Family a.39.1.5: Calmodulin-like: