Lineage for Family a.39.1.5: Calmodulin-like

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2319424Fold a.39: EF Hand-like [47472] (4 superfamilies)
    core: 4 helices; array of 2 hairpins, opened
  4. 2319425Superfamily a.39.1: EF-hand [47473] (12 families) (S)
    Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
  5. 2319893Family a.39.1.5: Calmodulin-like [47502] (24 proteins)
    Duplication: made with two pairs of EF-hands

Proteins:

  1. 2319894Calcineurin B-like protein 2 [101182] (1 species)
  2. 2319898Calcineurin regulatory subunit (B-chain) [47530] (3 species)
    1. 2319899Species Cow (Bos taurus) [TaxId:9913] [47531] (1 PDB entry)
    2. 2319901Species Human (Homo sapiens) [TaxId:9606] [47532] (8 PDB entries)
    3. 2319912Species Mouse (Mus musculus) [TaxId:10090] [272883] (1 PDB entry)
  3. 2319914Calcium vector protein [47514] (1 species)
  4. 2319920Calcium- and integrin-binding protein, CIB [47541] (1 species)
  5. 2319926Calcium-dependent protein kinase sk5 CLD [109821] (1 species)
  6. 2319930Calcium-regulated photoprotein [47512] (4 species)
    structurally most similar to sarcoplasmic calcium-binding protein
    1. 2319931Species Hydrozoa (Obelia geniculata), obelin [TaxId:185004] [63542] (1 PDB entry)
    2. 2319933Species Hydrozoa (Obelia longissima), obelin [TaxId:32570] [63541] (8 PDB entries)
      Uniprot Q27709
    3. 2319942Species Jellyfish (Aequorea aequorea), aequorin [TaxId:168712] [47513] (1 PDB entry)
    4. 2319945Species Jellyfish (Aequorea victoria), aequorin 1 [TaxId:6100] [116901] (1 PDB entry)
      Uniprot P07164 16-196
  7. 2319947Calerythrin [101179] (1 species)
    structurally most similar to sarcoplasmic calcium-binding protein
  8. 2319950Calmodulin [47516] (12 species)
    1. 2319951Species African clawed frog (Xenopus laevis) [TaxId:8355] [47521] (25 PDB entries)
    2. 2319975Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [89052] (4 PDB entries)
    3. 2319980Species Chicken (Gallus gallus) [TaxId:9031] [47520] (10 PDB entries)
      mutant with a two residue deletion in the central helix
    4. 2319993Species Ciliate (Paramecium tetraurelia) [TaxId:5888] [47523] (7 PDB entries)
      Uniprot Q42478
    5. 2320002Species Cow (Bos taurus) [TaxId:9913] [47518] (16 PDB entries)
      Uniprot P62157
    6. 2320020Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [47522] (13 PDB entries)
    7. 2320038Species Human (Homo sapiens) [TaxId:9606] [47517] (98 PDB entries)
      Uniprot P02593
    8. 2320210Species Mouse (Mus musculus) [TaxId:10090] [224847] (3 PDB entries)
    9. 2320226Species Nematode (Caenorhabditis elegans) [TaxId:6239] [89051] (1 PDB entry)
    10. 2320228Species Norway rat (Rattus norvegicus) [TaxId:10116] [158477] (17 PDB entries)
    11. 2320262Species Potato (Solanum tuberosum) [TaxId:4113] [109820] (1 PDB entry)
    12. Species Rat (Rattus rattus) [TaxId:10117] [47519] (1 PDB entry)
      Uniprot P62161
  9. 2320266Calmodulin-related protein NB-1 (CLP) [74721] (1 species)
  10. 2320269Calmodulin-related protein T21P5.17 [109823] (1 species)
  11. 2320272Caltractin (centrin 2) [89053] (2 species)
    1. 2320273Species Green alga (Chlamydomonas reinhardtii) [TaxId:3055] [89055] (1 PDB entry)
    2. Species Human (Homo sapiens) [TaxId:9606] [89054] (1 PDB entry)
  12. 2320277Cdc4p [63543] (1 species)
  13. 2320280EHCABP [69021] (1 species)
  14. 2320286Frequenin (neuronal calcium sensor 1) [47535] (3 species)
    1. 2320287Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [47536] (2 PDB entries)
    2. 2320290Species Human (Homo sapiens) [TaxId:9606] [63545] (2 PDB entries)
    3. 2320297Species Norway rat (Rattus norvegicus) [TaxId:10116] [228901] (2 PDB entries)
  15. 2320302Guanylate cyclase activating protein 2, GCAP-2 [47537] (1 species)
  16. 2320305Kchip1, Kv4 potassium channel-interacting protein [101184] (2 species)
    1. 2320306Species Human (Homo sapiens) [TaxId:9606] [116902] (1 PDB entry)
      Uniprot Q9NZI2
    2. 2320308Species Norway rat (Rattus norvegicus) [TaxId:10116] [101185] (1 PDB entry)
  17. 2320310Myosin Essential Chain [47524] (3 species)
    1. 2320311Species Bay scallop (Aequipecten irradians) [TaxId:31199] [47525] (13 PDB entries)
      Uniprot P13543
    2. 2320326Species Chicken (Gallus gallus) [TaxId:9031] [47526] (4 PDB entries)
    3. 2320338Species Human (Homo sapiens) [TaxId:9606] [101181] (1 PDB entry)
  18. 2320340Myosin Light Chain Mlc1p [81756] (1 species)
    light chain of class V myosin
  19. 2320346Myosin Regulatory Chain [47527] (2 species)
    1. 2320347Species Bay scallop (Aequipecten irradians) [TaxId:31199] [47528] (15 PDB entries)
      Uniprot P07291
    2. 2320364Species Chicken (Gallus gallus) [TaxId:9031] [47529] (1 PDB entry)
  20. 2320366Neurocalcin [47539] (1 species)
  21. 2320370Recoverin [47533] (1 species)
    Calcium-myristoyl switch; only one EF-hand is functional
  22. 2320386Sarcoplasmic calcium-binding protein [47509] (2 species)
    1. 2320387Species Amphioxus (Branchiostoma lanceolatum) [TaxId:7740] [47511] (1 PDB entry)
    2. 2320389Species Sandworm (Nereis diversicolor) [TaxId:126592] [47510] (2 PDB entries)
      Uniprot P04571
  23. 2320393Troponin C [47503] (6 species)
    1. 2320394Species Chicken (Gallus gallus) [TaxId:9031] [47504] (28 PDB entries)
      Uniprot P09860
    2. 2320426Species Chicken (Gallus gallus), cardiac isoform [TaxId:9031] [47507] (1 PDB entry)
    3. 2320428Species Human (Homo sapiens), cardiac isoform [TaxId:9606] [47508] (28 PDB entries)
    4. 2320462Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [47506] (4 PDB entries)
    5. 2320467Species Rainbow trout (Oncorhynchus mykiss) [TaxId:8022] [109819] (2 PDB entries)
      Uniprot Q7ZZB9 1-89
    6. 2320470Species Turkey (Meleagris gallopavo) [TaxId:9103] [47505] (2 PDB entries)
  24. 2320473automated matches [190064] (22 species)
    not a true protein
    1. 2320474Species African clawed frog (Xenopus laevis) [TaxId:8355] [225045] (1 PDB entry)
    2. 2320476Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [188855] (3 PDB entries)
    3. 2320484Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [255436] (1 PDB entry)
    4. 2320486Species Bay scallop (Argopecten irradians) [TaxId:31199] [189156] (2 PDB entries)
    5. 2320489Species Chicken (Gallus gallus) [TaxId:9031] [187205] (3 PDB entries)
    6. 2320493Species Cow (Bos taurus) [TaxId:9913] [228970] (3 PDB entries)
    7. 2320497Species Entamoeba histolytica [TaxId:294381] [225835] (3 PDB entries)
    8. 2320504Species Entamoeba histolytica [TaxId:885319] [342565] (1 PDB entry)
    9. 2320511Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [258881] (6 PDB entries)
    10. 2320521Species Human (Homo sapiens) [TaxId:9606] [186813] (12 PDB entries)
    11. 2320541Species Jellyfish (Aequorea victoria) [TaxId:6100] [186782] (5 PDB entries)
    12. 2320550Species Kluyveromyces lactis [TaxId:284590] [195890] (1 PDB entry)
    13. 2320555Species Mitrocoma cellularia [TaxId:31874] [261220] (1 PDB entry)
    14. 2320558Species Mouse (Mus musculus) [TaxId:10090] [187204] (1 PDB entry)
    15. 2320561Species Obelia longissima [TaxId:32570] [237068] (4 PDB entries)
    16. 2320567Species Opsanus tau [TaxId:8068] [255491] (1 PDB entry)
    17. 2320569Species Placopecten magellanicus [TaxId:6577] [189594] (3 PDB entries)
    18. 2320582Species Scherffelia dubia [TaxId:3190] [189616] (1 PDB entry)
    19. 2320585Species Soybean (Glycine max) [TaxId:3847] [255584] (3 PDB entries)
    20. 2320589Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [194524] (2 PDB entries)
    21. 2320593Species Todarodes pacificus [TaxId:6637] [189006] (1 PDB entry)
    22. 3055394Species Rattus norvegicus [TaxId:10116] [355456] (2 PDB entries)

More info for Family a.39.1.5: Calmodulin-like

Timeline for Family a.39.1.5: Calmodulin-like: