Lineage for Protein: Troponin C

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2710066Fold a.39: EF Hand-like [47472] (4 superfamilies)
    core: 4 helices; array of 2 hairpins, opened
  4. 2710067Superfamily a.39.1: EF-hand [47473] (12 families) (S)
    Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
  5. 2710548Family a.39.1.5: Calmodulin-like [47502] (24 proteins)
    Duplication: made with two pairs of EF-hands
  6. 2711123Protein Troponin C [47503] (6 species)

Species:

  1. 2711124Chicken (Gallus gallus) [TaxId:9031] [47504] (28 PDB entries)
    Uniprot P09860
    1. Domain for 1aj4:
    2. Domains for 1avs:
      1. 2711129Domain d1avsa_: 1avs A: [17226]
        calcium-saturated N-terminal domain
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
      2. 2711130Domain d1avsb_: 1avs B: [17227]
        calcium-saturated N-terminal domain
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
    3. Domain for 1blq:
      • 2711154Domain d1blqa_: 1blq A: [17240]
        N-domain only
        fragment; missing more than one-third of the common structure and/or sequence
    4. Domains for 1cta:
      1. 2711136Domain d1ctaa_: 1cta A: [17232]
        fragment, corresponding to the 3rd EF-hand
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
      2. 2711137Domain d1ctab_: 1cta B: [17233]
        fragment, corresponding to the 3rd EF-hand
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
    5. Domains for 1ctd:
      1. 2711134Domain d1ctda_: 1ctd A: [17230]
        fragment, corresponding to the 3rd EF-hand
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
      2. 2711135Domain d1ctdb_: 1ctd B: [17231]
        fragment, corresponding to the 3rd EF-hand
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
    6. Domain for 1dtl:
    7. Domain for 1jc2:
      • 2711144Domain d1jc2a_: 1jc2 A: [62862]
        C-domain only
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
    8. Domain for 1la0:
      • 2711145Domain d1la0a_: 1la0 A: [77864]
        calcium saturated troponin C bound to troponin I
        complexed with ca
    9. Domain for 1ncx:
    10. Domain for 1ncy:
    11. Domain for 1ncz:
    12. Domain for 1npq:
      • 2711151Domain d1npqa_: 1npq A: [85983]
        calcium saturated troponin C bound to troponin I fragment, chain B
        complexed with ca; mutant

        fragment; missing more than one-third of the common structure and/or sequence
    13. Domain for 1pon:
      • 2711148Domain d1pon.1: 1pon A:,B: [17239]
        heterodimer of 3rd and 4th EF-hands
        fragment; missing more than one-third of the common structure and/or sequence
    14. Domain for 1sbj:
      • 2711141Domain d1sbja_: 1sbj A: [112064]
        C-terminal domain
        complexed with mg

        fragment; missing more than one-third of the common structure and/or sequence
    15. Domain for 1scv:
      • 2711142Domain d1scva_: 1scv A: [112072]
        C-terminal domain
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
    16. Domain for 1skt:
      • 2711149Domain d1skta_: 1skt A: [17243]
        N-domain only
        fragment; missing more than one-third of the common structure and/or sequence
    17. Domain for 1smg:
      • 2711143Domain d1smga_: 1smg A: [17234]
        N-domain only
        complexed with ca; mutant

        fragment; missing more than one-third of the common structure and/or sequence
    18. Domain for 1tnp:
      • 2711152Domain d1tnpa_: 1tnp A: [17238]
        N-domain only
        fragment; missing more than one-third of the common structure and/or sequence
    19. Domain for 1tnq:
      • 2711153Domain d1tnqa_: 1tnq A: [17245]
        N-domain only
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
    20. Domain for 1tnw:
    21. Domain for 1tnx:
    22. Domain for 1top:
    23. Domain for 1ytz:
    24. Domain for 1yv0:
    25. Domain for 1zac:
      • 2711138Domain d1zaca_: 1zac A: [17236]
        N-domain only
        fragment; missing more than one-third of the common structure and/or sequence
    26. Domain for 2ctn:
      • 2711150Domain d2ctna_: 2ctn A: [17242]
        N-domain only; C-terminal domain is in 3CTN
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
    27. Domain for 3ctn:
      • 2711146Domain d3ctna_: 3ctn A: [17241]
        C-domain only; N-terminal domain is in 2CTN
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
    28. Domain for 4tnc:
  2. 2711156Chicken (Gallus gallus), cardiac isoform [TaxId:9031] [47507] (1 PDB entry)
    • Domain for 1fi5:
      • 2711157Domain d1fi5a_: 1fi5 A: [17252]
        C-domain only
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
  3. 2711158Human (Homo sapiens), cardiac isoform [TaxId:9606] [47508] (28 PDB entries)
    1. Domain for 1ap4:
      • 2711182Domain d1ap4a_: 1ap4 A: [17253]
        N-domain only
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
    2. Domain for 1ih0:
      • 2711188Domain d1ih0a_: 1ih0 A: [66140]
        C-domain only
        complexed with ca, emd

        fragment; missing more than one-third of the common structure and/or sequence
    3. Domains for 1j1d:
      1. 2711169Domain d1j1da_: 1j1d A: [83963]
        Other proteins in same PDB: d1j1db_, d1j1dc_, d1j1de_, d1j1df_
        complexed with ca
      2. 2711170Domain d1j1dd_: 1j1d D: [83966]
        Other proteins in same PDB: d1j1db_, d1j1dc_, d1j1de_, d1j1df_
        complexed with ca
    4. Domains for 1j1e:
      1. 2711171Domain d1j1ea_: 1j1e A: [83969]
        Other proteins in same PDB: d1j1eb_, d1j1ec_, d1j1ee_, d1j1ef_
        complexed with ca
      2. 2711172Domain d1j1ed_: 1j1e D: [83972]
        Other proteins in same PDB: d1j1eb_, d1j1ec_, d1j1ee_, d1j1ef_
        complexed with ca
    5. Domain for 1lxf:
      • 2711190Domain d1lxfc_: 1lxf C: [78292]
        Other proteins in same PDB: d1lxfi_
        N-domain only; complexed with a troponin I fragment
        complexed with bep, ca

        fragment; missing more than one-third of the common structure and/or sequence
    6. Domain for 1mxl:
      • 2711184Domain d1mxlc_: 1mxl C: [17255]
        Other proteins in same PDB: d1mxli_
        N-domain only; complexed with a troponin I fragment
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
    7. Domain for 1ozs:
      • 2711191Domain d1ozsa1: 1ozs A:90-161 [93857]
        Other proteins in same PDB: d1ozsa2
        N-domain only; complexed with a troponin I fragment; chain B
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
    8. Domain for 1spy:
      • 2711186Domain d1spya_: 1spy A: [17254]
        N-domain only
        fragment; missing more than one-third of the common structure and/or sequence
    9. Domain for 2hf5:
      • 2711176Domain d2hf5a1: 2hf5 A:81-113 [147275]
        automatically matched to d1ctaa_
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
    10. Domain for 2jt0:
    11. Domain for 2jt3:
    12. Domain for 2jt8:
    13. Domain for 2jtz:
    14. Domain for 2jxl:
      • 2711178Domain d2jxla_: 2jxl A: [242306]
        automated match to d3sd6a_
        complexed with ca; mutant

        fragment; missing more than one-third of the common structure and/or sequence
    15. Domain for 2kdh:
      • 2711187Domain d2kdha1: 2kdh A:91-161 [242470]
        Other proteins in same PDB: d2kdha2
        automated match to d1ozsa_
        complexed with ca, kdh

        fragment; missing more than one-third of the common structure and/or sequence
    16. Domain for 2kfx:
      • 2711177Domain d2kfxt_: 2kfx T: [242505]
        automated match to d3sd6a_
        complexed with ca, ww7

        fragment; missing more than one-third of the common structure and/or sequence
    17. Domain for 2kgb:
      • 2711180Domain d2kgbc_: 2kgb C: [264350]
        automated match to d2jxla_
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
    18. Domain for 2l98:
      • 2711181Domain d2l98a1: 2l98 A:91-161 [242813]
        Other proteins in same PDB: d2l98a2
        automated match to d1ozsa_
        complexed with ca, stl

        fragment; missing more than one-third of the common structure and/or sequence
    19. Domain for 2mle:
      • 2711174Domain d2mlec1: 2mle C:91-161 [243196]
        Other proteins in same PDB: d2mlec2
        automated match to d1ozsa_
        complexed with ca

        fragment; missing more than one-third of the common structure and/or sequence
    20. Domain for 2mlf:
      • 2711173Domain d2mlfc_: 2mlf C: [243197]
        automated match to d1ozsa_
        complexed with ca; mutant

        fragment; missing more than one-third of the common structure and/or sequence
    21. Domain for 2n79:
      • 2711175Domain d2n79c_: 2n79 C: [278710]
        automated match to d2kfxt_
        complexed with ca; mutant

        fragment; missing more than one-third of the common structure and/or sequence
    22. Domains for 3rv5:
      1. 2711162Domain d3rv5a_: 3rv5 A: [216078]
        automated match to d1mxlc_
        complexed with ca, cd, dxc

        fragment; missing more than one-third of the common structure and/or sequence
      2. 2711163Domain d3rv5b_: 3rv5 B: [216079]
        automated match to d1mxlc_
        complexed with ca, cd, dxc

        fragment; missing more than one-third of the common structure and/or sequence
      3. 2711164Domain d3rv5c_: 3rv5 C: [216080]
        automated match to d1mxlc_
        complexed with ca, cd, dxc

        fragment; missing more than one-third of the common structure and/or sequence
      4. 2711165Domain d3rv5d_: 3rv5 D: [216081]
        automated match to d1mxlc_
        complexed with ca, cd, dxc

        fragment; missing more than one-third of the common structure and/or sequence
    23. Domain for 3sd6:
      • 2711159Domain d3sd6a_: 3sd6 A: [216345]
        automated match to d1mxlc_
        complexed with act, ca, cd

        fragment; missing more than one-third of the common structure and/or sequence
    24. Domain for 3swb:
      • 2711161Domain d3swba_: 3swb A: [216585]
        automated match to d1mxlc_
        complexed with act, ca, cd

        fragment; missing more than one-third of the common structure and/or sequence
    25. Domain for 4gje:
      • 2711160Domain d4gjea_: 4gje A: [221955]
        automated match to d1mxlc_
        complexed with act, ca, cd

        fragment; missing more than one-third of the common structure and/or sequence
    26. Domain for 4gjf:
      • 2711166Domain d4gjfa_: 4gjf A: [221956]
        automated match to d4gjga_
        complexed with act, ca, cd, gol; mutant

        fragment; missing more than one-third of the common structure and/or sequence
    27. Domain for 4gjg:
      • 2711168Domain d4gjga_: 4gjg A: [193067]
        automated match to d1r2ua_
        complexed with act, ca, cd, gol; mutant

        fragment; missing more than one-third of the common structure and/or sequence
    28. Domain for 4y99:
  4. 2711192Rabbit (Oryctolagus cuniculus) [TaxId:9986] [47506] (4 PDB entries)
    1. Domain for 1a2x:
      • 2711196Domain d1a2xa_: 1a2x A: [17251]
        Other proteins in same PDB: d1a2xb_
        complexed with a 47 residue (1-47) fragment of troponin I
        complexed with ca
    2. Domain for 1tcf:
    3. Domain for 1tn4:
    4. Domain for 2tn4:
  5. 2711197Rainbow trout (Oncorhynchus mykiss) [TaxId:8022] [109819] (2 PDB entries)
    Uniprot Q7ZZB9 1-89
    1. Domain for 1r2u:
      • 2711198Domain d1r2ua_: 1r2u A: [104783]
        complexed with ca
        fragment; missing more than one-third of the common structure and/or sequence
    2. Domain for 1r6p:
      • 2711199Domain d1r6pa_: 1r6p A: [104822]
        complexed with ca
        fragment; missing more than one-third of the common structure and/or sequence
  6. 2711200Turkey (Meleagris gallopavo) [TaxId:9103] [47505] (2 PDB entries)
    1. Domain for 1trf:
      • 2711202Domain d1trfa_: 1trf A: [17247]
        N-terminal domain of two EF-hands
        fragment; missing more than one-third of the common structure and/or sequence
    2. Domain for 5tnc:

More info for Protein Troponin C from a.39.1.5: Calmodulin-like

Timeline for Protein Troponin C from a.39.1.5: Calmodulin-like: