SCOPe 2.08: Domain d1twca_: 1twc A:

Lineage for d1twca_ (1twc A:)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.29: beta and beta-prime subunits of DNA dependent RNA-polymerase [64483] (1 superfamily)
   Multidomain subunits of complex domain organization

4. Superfamily e.29.1: beta and beta-prime subunits of DNA dependent RNA-polymerase [64484] (3 families)
   The catalytic site is formed by the association of two double-psi beta-barrel domains, one from each subunit

5. Family e.29.1.2: RNA-polymerase beta-prime [64490] (4 proteins)

6. Protein RBP1 [64486] (2 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [64487] (24 PDB entries)
   Uniprot P04050; part of multichain biological unit

8. Domain d1twca_: 1twc A: [112711]
   Other proteins in same PDB: d1twcb_, d1twcc1, d1twcc2, d1twce1, d1twce2, d1twcf_, d1twch_, d1twci1, d1twci2, d1twcj_, d1twck_, d1twcl_
   protein/RNA complex; complexed with gtp, mn, zn

Details for d1twca_

PDB Entry: 1twc, 3 Å

PDB Description: RNA polymerase II complexed with GTP

PDB Compounds: (A:) DNA-directed RNA polymerase II largest subunit

SCOPe Domain Sequences for d1twca_:

Sequence, based on SEQRES records:

>d1twca_ e.29.1.2 (A:) RBP1 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
gqqyssaplrtvkevqfglfspeevraisvakirfpetmdetqtrakigglndprlgsid
rnlkcqtcqegmnecpghfghidlakpvfhvgfiakikkvcecvcmhcgkllldehnelm
rqalaikdskkrfaaiwtlcktkmvcetdvpseddptqlvsrggcgntqptirkdglklv
gswkkdratgdadepelrvlsteeilnifkhisvkdftslgfnevfsrpewmiltclpvp
pppvrpsisfnesqrgeddltfkladilkanisletlehngaphhaieeaesllqfhvat
ymdndiagqpqalqksgrpvksirarlkgkegrirgnlmgkrvdfsartvisgdpnleld
qvgvpksiaktltypevvtpynidrltqlvrngpnehpgakyvirdsgdridlryskrag
diqlqygwkverhimdndpvlfnrqpslhkmsmmahrvkvipystfrlnlsvtspynadf
dgdemnlhvpqseetraelsqlcavplqivspqsnkpcmgivqdtlcgirkltlrdtfie
ldqvlnmlywvpdwdgviptpaiikpkplwsgkqilsvaipngihlqrfdegttllspkd
ngmliidgqiifgvvekktvgssngglihvvtrekgpqvcaklfgniqkvvnfwllhngf
stgigdtiadgptmreitetiaeakkkvldvtkeaqanlltakhgmtlresfednvvrfl
neardkagrlaevnlkdlnnvkqmvmagskgsfiniaqmsacvgqqsvegkriafgfvdr
tlphfskddyspeskgfvensylrgltpqefffhamggreglidtavktaetgyiqrrlv
kaledimvhydnttrnslgnviqfiygedgmdaahiekqsldtiggsdaafekryrvdll
ntdhtldpsllesgseilgdlklqvlldeeykqlvkdrkflrevfvdgeanwplpvnirr
iiqnaqqtfhidhtkpsdltikdivlgvkdlqenllvlrgkneiiqnaqrdavtlfccll
rsrlatrrvlqeyrltkqafdwvlsnieaqflrsvvhpgemvgvlaaqsigepatqmtln
tfhfagvaskkvtsgvprlkeilnvaknmktpsltvylepghaadqeqaklirsaiehtt
lksvtiaseiyydpdprstvipedeeiiqlhfslldeeaeqsfdqqspwllrleldraam
ndkdltmgqvgerikqtfkndlfviwsedndekliircrvvrpksldaeteaeedhmlkk
ientmlenitlrgveniervvmmkydrkvpsptgeyvkepewvletdgvnlsevmtvpgi
dptriytnsfidimevlgieagraalykevynviasdgsyvnyrhmallvdvmttqgglt
svtrhgfnrsntgalmrcsfeetveilfeagasaelddcrgvsenvilgqmapigtgafd
vmideesl

Sequence, based on observed residues (ATOM records):

>d1twca_ e.29.1.2 (A:) RBP1 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
gqqyssaplrtvkevqfglfspeevraisvakirfpetmdetqtrakigglndprlgsid
rnlkcqtcqegmnecpghfghidlakpvfhvgfiakikkvcecvcmhcgkllldehnelm
rqalaikdskkrfaaiwtlcktkmvcetdvpseddptqlvsrggcgntqptirkdglklv
gswkkdratgdadepelrvlsteeilnifkhisvkdftslgfnevfsrpewmiltclpvp
pppvrpdltfkladilkanisletlehngaphhaieeaesllqfhvatymdsirarldfs
artvisgdpnleldqvgvpksiaktltypevvtpynidrltqlvrngpnehpgakyvird
sgdridlryskragdiqlqygwkverhimdndpvlfnrqpslhkmsmmahrvkvipystf
rlnlsvtspynadfdgdemnlhvpqseetraelsqlcavplqivspqsnkpcmgivqdtl
cgirkltlrdtfieldqvlnmlywvpdwdgviptpaiikpkplwsgkqilsvaipngihl
qrfdegttllspkdngmliidgqiifgvvekktvgssngglihvvtrekgpqvcaklfgn
iqkvvnfwllhngfstgigdtiadgptmreitetiaeakkkvldvtkeaqanlltakhgm
tlresfednvvrflneardkagrlaevnlkdlnnvkqmvmagskgsfiniaqmsacvgqq
svegkriafgfvdrtlphfskddyspeskgfvensylrgltpqefffhamggreglidta
vktaetgyiqrrlvkaledimvhydnttrnslgnviqfiygedgmdaahiekqsldtigg
sdaafekryrvdllntdhtldpsllesgseilgdlklqvlldeeykqlvkdrkflrevfv
dgeanwplpvnirriiqnaqqtfhidhtkpsdltikdivlgvkdlqenllvlrgkneiiq
naqrdavtlfccllrsrlatrrvlqeyrltkqafdwvlsnieaqflrsvvhpgemvgvla
aqsigepatqmtlkkvtsgvprlkeilnvaknmktpsltvylepghaadqeqaklirsai
ehttlksvtiaseiyydpdprstvipedeeiiqlhlqqspwllrleldraamndkdltmg
qvgerikqtfkndlfviwsedndekliircrvvaeedhmlkkientmlenitlrgvenie
rvvmmkydrkvpsptgeyvkepewvletdgvnlsevmtvpgidptriytnsfidimevlg
ieagraalykevynviasdgsyvnyrhmallvdvmttqggltsvttveilfeagasaeld
dcrgvsenvilgqmapigtgafdvmideesl

Timeline for d1twca_:

• d1twca_ first appeared in SCOP 1.71
  
• d1twca_ appears in SCOPe 2.07