PDB entry 5fnv

View 5fnv on RCSB PDB site
Description: a new complex structure of tubulin with an alpha-beta unsaturated lactone
Class: structural protein
Keywords: structural protein, tubulin complex alpha-beta unsaturated lactone
Deposited on 2015-11-16, released 2016-05-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-07-13, with a file datestamp of 2016-07-08.
Experiment type: XRAY
Resolution: 2.61 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tubulin alpha-1B chain
    Species: Gallus gallus [TaxId:9031]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fnva1, d5fnva2
  • Chain 'B':
    Compound: Tubulin beta chain
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fnvb1, d5fnvb2
  • Chain 'C':
    Compound: Tubulin alpha-1B chain
    Species: Gallus gallus [TaxId:9031]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fnvc1, d5fnvc2
  • Chain 'D':
    Compound: Tubulin beta chain
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fnvd1, d5fnvd2
  • Chain 'E':
    Compound: Stathmin-4
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5fnve_
  • Chain 'F':
    Compound: tubulin tyrosine ligase
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
    • Uniprot E1BQ43 (0-377)
      • expression tag (378-383)
    Domains in SCOPe 2.08: d5fnvf1, d5fnvf2, d5fnvf3
  • Heterogens: GTP, MG, CA, GDP, MES, X3H, ACP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5fnvA (A:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsdktigggddsfntffsetgagk
hvpravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvld
rirkladqctglqgflvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvsta
vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrlisqivssita
slrfdgalnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepan
qmvkcdprhgkymaccllyrgdvvpkdvnaaiatiktkrsiqfvdwcptgfkvginyqpp
tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
aredmaalekdyeevgvdsvegegeeegeey

    Sequence, based on observed residues (ATOM records): (download) 
    >5fnvA (A:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsdktigggddsfntffsetgagk
hvpravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvld
rirkladqctglqgflvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvsta
vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrlisqivssita
slrfdgaqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepanqmvkcdpr
hgkymaccllyrgdvvpkdvnaaiatiktkrsiqfvdwcptgfkvginyqpptvvpggdl
akvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefsearedmaal
ekdyeevgv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5fnvB (B:)
mreivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneaagnkyv
prailvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvvpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdaknmm
aacdprhgryltvaavfrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprg
lkmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
eyqqyqdatadeqgefeeegeedea

    Sequence, based on observed residues (ATOM records): (download) 
    >5fnvB (B:)
reivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyynekyvprail
vdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvvrkese
scdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvvpspkvsdtvvepyna
tlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttclrfpgq
lnadlrklavnmvpfprlhffmpgfapltsqyraltvpeltqqmfdaknmmaacdprhgr
yltvaavfrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprglkmsatfig
nstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvseyqqyqda

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5fnvC (C:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsdktigggddsfntffsetgagk
hvpravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvld
rirkladqctglqgflvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvsta
vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrlisqivssita
slrfdgalnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepan
qmvkcdprhgkymaccllyrgdvvpkdvnaaiatiktkrsiqfvdwcptgfkvginyqpp
tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
aredmaalekdyeevgvdsvegegeeegeey

    Sequence, based on observed residues (ATOM records): (download) 
    >5fnvC (C:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsdktigggddsfntffsetgagk
hvpravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvld
rirkladqctglqgflvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvsta
vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrlisqivssita
slrfdgalnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepan
qmvkcdprhgkymaccllyrgdvvpkdvnaaiatiktkrsiqfvdwcptgfkvginyqpp
tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
aredmaalekdyeevgvds

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5fnvD (D:)
mreivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneaagnkyv
prailvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvvpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdaknmm
aacdprhgryltvaavfrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprg
lkmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
eyqqyqdatadeqgefeeegeedea

    Sequence, based on observed residues (ATOM records): (download) 
    >5fnvD (D:)
reivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneaagnkyvp
railvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvvr
kesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvvpspkvsdtvve
pynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttclr
fpgqlnadlrklavnmvpfprlhffmpgfaplltvpeltqqmfdaknmmaacdprhgryl
tvaavfrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprglkmsatfigns
taiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvseyqqyqdata

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5fnvE (E:)
madmevielnkctsgqsfevilkppsfdgvpefnaslprrrdpsleeiqkkleaaeerrk
yqeaellkhlaekrehereviqkaieennnfikmakeklaqkmesnkenreahlaamler
lqekdkhaeevrknkelkeeasr

    Sequence, based on observed residues (ATOM records): (download) 
    >5fnvE (E:)
mevielnkctsgqsfevilkppdpsleeiqkkleaaeerrkyqeaellkhlaekrehere
viqkaieennnfikmakeklaqkmesnkenreahlaamlerlqekdkhaeevrknkelk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5fnvF (F:)
mytfvvrdenssvyaevsrlllatgqwkrlrkdnprfnlmlgernrlpfgrlghepglvq
lvnyyrgadklcrkaslvkliktspelsesctwfpesyviyptnlktpvapaqngirhli
nntrtderevflaaynrrregregnvwiakssagakgegilisseaselldfideqgqvh
viqkylekplllepghrkfdirswvlvdhlyniylyregvlrtssepynsanfqdktchl
tnhciqkeysknygryeegnemffeefnqylmdalnttlensillqikhiirsclmciep
aistkhlhyqsfqlfgfdfmvdeelkvwlievngapacaqklyaelcqgivdvaissvfp
ladtgqktsqptsifiklhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5fnvF (F:)
mytfvvrdenssvyaevsrlllatgqwkrlrkdnprfnlmlgernrlpfgrlghepglvq
lvnyyrgadklcrkaslvkliktspelsesctwfpesyviyptgnvwiakgilisseahv
iqkylekplllepghrkfdirswvlvdhlyniylyregvlrtssepynsanfqdktchlt
nhciqknygryeegnemffeefnqylmdalnttlensillqikhiirsclmciepaistk
hlhyqsfqlfgfdfmvdeelkvwlievngapacaqklyaelcqgivdvaissvfplsifi
klhhhhhh