SCOPe 2.08: Domain d6syha_: 6syh A:

Lineage for d6syha_ (6syh A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.88: Glutaminase/Asparaginase [53773] (1 superfamily)
   consists of two non-similar alpha/beta domains, 3 layers (a/b/a) each
   Domain 1 has mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest; left-handed crossover connection between strands 4 and 5
   Domain 2 has parallel beta-sheet of 4 strands, order 1234

4. Superfamily c.88.1: Glutaminase/Asparaginase [53774] (2 families)

5. Family c.88.1.1: Glutaminase/Asparaginase [53775] (4 proteins)
   automatically mapped to Pfam PF00710

6. Protein Asparaginase type II [53776] (5 species)

7. Species Wolinella succinogenes [TaxId:273121] [332353] (8 PDB entries)

8. Domain d6syha_: 6syh A: [375896]
   automated match to d5k45a_
   mutant

Details for d6syha_

PDB Entry: 6syh, 1.5 Å

PDB Description: wolinella succinogenes l-asparaginase mutant v23q,k24t in p 22121

PDB Compounds: (A:) L-asparaginase

SCOPe Domain Sequences for d6syha_:

Sequence, based on SEQRES records:

>d6syha_ c.88.1.1 (A:) Asparaginase type II {Wolinella succinogenes [TaxId: 273121]}
kpqvtilatggtiagsgessktssysagavtvdkllaavpaindlatikgeqissigsqe
mtgkvwlklakrvnellaqketeaviithgtdtmeetafflnltvksqkpvvlvgamrpg
ssmsadgpmnlynavnvainkastnkgvvivmndeihaareatklnttavnafaspntgk
igtvyygkveyftqsvrphtlasefdiskieelprvdilyahpddtdvlvnaalqagakg
iihagmgngnpfpltqnalekaaksgvvvarssrvgsgsttqeaevddkklgfvatesln
pqkarvllmlaltktsdreaiqkifsty

Sequence, based on observed residues (ATOM records):

>d6syha_ c.88.1.1 (A:) Asparaginase type II {Wolinella succinogenes [TaxId: 273121]}
kpqvtilatggtiagsagavtvdkllaavpaindlatikgeqissigsqemtgkvwlkla
krvnellaqketeaviithgtdtmeetafflnltvksqkpvvlvgamrpgssmsadgpmn
lynavnvainkastnkgvvivmndeihaareatklnttavnafaspntgkigtvyygkve
yftqsvrphtlasefdiskieelprvdilyahpddtdvlvnaalqagakgiihagmgngn
pfpltqnalekaaksgvvvarssrvgsgsttqeaevddkklgfvateslnpqkarvllml
altktsdreaiqkifsty

Timeline for d6syha_:

• d6syha_ first appeared in SCOPe 2.07