SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Family c.88.1.1: Glutaminase/Asparaginase

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2142620Fold c.88: Glutaminase/Asparaginase [53773] (1 superfamily)
    consists of two non-similar alpha/beta domains, 3 layers (a/b/a) each
    Domain 1 has mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest; left-handed crossover connection between strands 4 and 5
    Domain 2 has parallel beta-sheet of 4 strands, order 1234
  4. 2142621Superfamily c.88.1: Glutaminase/Asparaginase [53774] (2 families) (S)
  5. 2142622Family c.88.1.1: Glutaminase/Asparaginase [53775] (4 protein domains)
    automatically mapped to Pfam PF00710

Protein Domains:

  1. 2142623Asparaginase type II [53776] (5 species)
    1. 2142624Species Erwinia chrysanthemi [TaxId:556] [53779] (8 PDB entries)
    2. 2142653Species Escherichia coli [TaxId:562] [53777] (7 PDB entries)
    3. 2142676Species Vibrio cholerae [TaxId:666] [159797] (2 PDB entries)
      Uniprot Q9KQK3 2-337
    4. 2142685Species Wolinella succinogenes [TaxId:844] [53778] (1 PDB entry)
    5. 2289052Species Wolinella succinogenes [TaxId:273121] [332353] (4 PDB entries)
  2. 2142688Glutaminase-asparaginase [53780] (2 species)
    1. 2142689Species Acinetobacter glutaminasificans [TaxId:474] [53781] (1 PDB entry)
    2. 2142691Species Pseudomonas sp., 7A [TaxId:306] [53782] (4 PDB entries)
  3. 2142702Glutamyl-tRNA(Gln) amidotransferase subunit D, GatD [142776] (2 species)
    1. 2142703Species Methanobacterium thermoautotrophicum [TaxId:145262] [142778] (1 PDB entry)
      Uniprot O26802 84-435
    2. 2142705Species Pyrococcus abyssi [TaxId:29292] [142777] (1 PDB entry)
      Uniprot Q9V0T9 76-438
  4. 2142708automated matches [190446] (8 species)
    not a true protein
    1. 2142709Species Escherichia coli [TaxId:562] [225264] (3 PDB entries)
    2. Species Methanothermobacter thermautotrophicus [TaxId:145262] [255110] (1 PDB entry)
    3. 2142724Species Pectobacterium atrosepticum [TaxId:218491] [255007] (1 PDB entry)
    4. 2142733Species Pectobacterium atrosepticum [TaxId:29471] [187353] (2 PDB entries)
    5. 2142754Species Pectobacterium carotovorum [TaxId:554] [188521] (1 PDB entry)
    6. 2142763Species Yersinia pestis [TaxId:214092] [189425] (1 PDB entry)
    7. 2270579Species Dickeya chrysanthemi [TaxId:556] [313884] (5 PDB entries)
    8. 2289049Species Wolinella succinogenes [TaxId:273121] [332350] (1 PDB entry)

More info for Family c.88.1.1: Glutaminase/Asparaginase

Timeline for Family c.88.1.1: Glutaminase/Asparaginase: