SCOPe 2.05: Domain d3mhub_: 3mhu B:

Lineage for d3mhub_ (3mhu B:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families)

5. Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 proteins)

6. Protein automated matches [190228] (15 species)
   not a true protein

7. Species Leishmania major [TaxId:347515] [255968] (3 PDB entries)

8. Domain d3mhub_: 3mhu B: [247708]
   automated match to d3c61a_
   complexed with ejz, fmn, gol, so4

Details for d3mhub_

PDB Entry: 3mhu, 1.85 Å

PDB Description: Crystal structure of dihydroorotate dehydrogenase from Leishmania major in complex with 5-Nitroorotic acid

PDB Compounds: (B:) dihydroorotate dehydrogenase

SCOPe Domain Sequences for d3mhub_:

Sequence, based on SEQRES records:

>d3mhub_ c.1.4.1 (B:) automated matches {Leishmania major [TaxId: 347515]}
gsmslqvnllnntfanpfmnaagvmcttteelvamtesasgslvsksctpalregnptpr
yqalplgsinsmglpnngfdfylayaaeqhdygkkplflsmsglsmrenvemckrlaava
tekgvilelnlscpnvpgkpqvaydfdamrqcltavsevyphsfgvkmppyfdfahfdaa
aeilnefpkvqfitcinsignglvidaetesvvikpkqgfgglggryvlptalaninafy
rrcpgklifgcggvytgedaflhvlagasmvqvgtalqeegpsiferltsellgvmakkr
yqtldefrgkvrtl

Sequence, based on observed residues (ATOM records):

>d3mhub_ c.1.4.1 (B:) automated matches {Leishmania major [TaxId: 347515]}
gsmslqvnllnntfanpfmnaagvmcttteelvamtesasgslvsksctpalregnptpr
yqalplgsinsmglpnngfdfylayaaeqhdygkkplflsmsglsmrenvemckrlaava
tekgvilelnlscpqvaydfdamrqcltavsevyphsfgvkmppyfdfahfdaaaeilne
fpkvqfitcinsignglvidaetesvvikpkqgfgglggryvlptalaninafyrrcpgk
lifgcggvytgedaflhvlagasmvqvgtalqeegpsiferltsellgvmakkryqtlde
frgkvrtl

Timeline for d3mhub_:

• d3mhub_ first appeared in SCOPe 2.04
  
• d3mhub_ is called d3mhub1 in SCOPe 2.06
  
• d3mhub_ appears in the current release, SCOPe 2.08, called d3mhub1