SCOPe 2.08: Domain d3mhub1: 3mhu B:1-312

Lineage for d3mhub1 (3mhu B:1-312)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families)

5. Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 proteins)

6. Protein automated matches [190228] (20 species)
   not a true protein

7. Species Leishmania major [TaxId:347515] [255968] (3 PDB entries)

8. Domain d3mhub1: 3mhu B:1-312 [247708]
   Other proteins in same PDB: d3mhua2, d3mhub2
   automated match to d3c61a_
   complexed with ejz, fmn, gol, so4

Details for d3mhub1

PDB Entry: 3mhu, 1.85 Å

PDB Description: Crystal structure of dihydroorotate dehydrogenase from Leishmania major in complex with 5-Nitroorotic acid

PDB Compounds: (B:) dihydroorotate dehydrogenase

SCOPe Domain Sequences for d3mhub1:

Sequence, based on SEQRES records:

>d3mhub1 c.1.4.1 (B:1-312) automated matches {Leishmania major [TaxId: 347515]}
mslqvnllnntfanpfmnaagvmcttteelvamtesasgslvsksctpalregnptpryq
alplgsinsmglpnngfdfylayaaeqhdygkkplflsmsglsmrenvemckrlaavate
kgvilelnlscpnvpgkpqvaydfdamrqcltavsevyphsfgvkmppyfdfahfdaaae
ilnefpkvqfitcinsignglvidaetesvvikpkqgfgglggryvlptalaninafyrr
cpgklifgcggvytgedaflhvlagasmvqvgtalqeegpsiferltsellgvmakkryq
tldefrgkvrtl

Sequence, based on observed residues (ATOM records):

>d3mhub1 c.1.4.1 (B:1-312) automated matches {Leishmania major [TaxId: 347515]}
mslqvnllnntfanpfmnaagvmcttteelvamtesasgslvsksctpalregnptpryq
alplgsinsmglpnngfdfylayaaeqhdygkkplflsmsglsmrenvemckrlaavate
kgvilelnlscpqvaydfdamrqcltavsevyphsfgvkmppyfdfahfdaaaeilnefp
kvqfitcinsignglvidaetesvvikpkqgfgglggryvlptalaninafyrrcpgkli
fgcggvytgedaflhvlagasmvqvgtalqeegpsiferltsellgvmakkryqtldefr
gkvrtl

Timeline for d3mhub1:

• d3mhub1 first appeared in SCOPe 2.04, called d3mhub_
  
• d3mhub1 appears in SCOPe 2.07