PDB entry 5mp6

View 5mp6 on RCSB PDB site
Description: Structure of the Unliganded Fab from HIV-1 Neutralizing Antibody CAP248-2B that Binds to the gp120 C-terminus - gp41 Interface, at two Angstrom resolution.
Class: immune system
Keywords: HIV, neutralizing antibody, gp120 C-terminus, CAP248, gp120-gp41 interface, IMMUNE SYSTEM
Deposited on 2016-12-15, released 2016-12-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-11, with a file datestamp of 2020-03-06.
Experiment type: XRAY
Resolution: 1.96 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: CAP248-2B Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5MP6 (0-End)
    Domains in SCOPe 2.08: d5mp6h_
  • Chain 'L':
    Compound: CAP248-2B Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5MP6 (0-224)
    Domains in SCOPe 2.08: d5mp6l1, d5mp6l2
  • Chain 'P':
    Compound: CAP248-2B Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5MP6 (0-End)
    Domains in SCOPe 2.08: d5mp6p_
  • Chain 'Q':
    Compound: CAP248-2B Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5MP6 (0-End)
    Domains in SCOPe 2.08: d5mp6q1, d5mp6q2
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5mp6H (H:)
evqlqqsgpglvkpsqtlsltcnvygvaisnedyywtwirqhpgkglewigdiyynsgtt
hynpslksrasvsvdlsrnqftlkvtsvttadaavyycareastkitddggafdfwgrgt
mvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfp
avlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkglevlfq

    Sequence, based on observed residues (ATOM records): (download) 
    >5mp6H (H:)
evqlqqsgpglvkpsqtlsltcnvygvaisnedyywtwirqhpgkglewigdiyynsgtt
hynpslksrasvsvdlsrnqftlkvtsvttadaavyycareastkitddggafdfwgrgt
mvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfp
avlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscd

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5mp6L (L:)
esaltqpasvsgspgqsisisctgtssdiggykyvswyqqhpgrapkliiydvikrpsgi
sdrfsgsksantasltisglqagdeasyycssyttkktsffgpatrayvfgsgtqvtvlg
qpkanptvtlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskq
snnkyaassylsltpeqwkshksyscqvthegstvektvaptecs

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >5mp6P (P:)
evqlqqsgpglvkpsqtlsltcnvygvaisnedyywtwirqhpgkglewigdiyynsgtt
hynpslksrasvsvdlsrnqftlkvtsvttadaavyycareastkitddggafdfwgrgt
mvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfp
avlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkglevlfq

    Sequence, based on observed residues (ATOM records): (download) 
    >5mp6P (P:)
evqlqqsgpglvkpsqtlsltcnvygvaisnedyywtwirqhpgkglewigdiyynsgtt
hynpslksrasvsvdlsrnqftlkvtsvttadaavyycareastkitddggafdfwgrgt
mvtvssastkgpsvfplapclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkkv

  • Chain 'Q':
    Sequence, based on SEQRES records: (download) 
    >5mp6Q (Q:)
esaltqpasvsgspgqsisisctgtssdiggykyvswyqqhpgrapkliiydvikrpsgi
sdrfsgsksantasltisglqagdeasyycssyttkktsffgpatrayvfgsgtqvtvlg
qpkanptvtlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskq
snnkyaassylsltpeqwkshksyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5mp6Q (Q:)
esaltqpasvsgspgqsisisctgtssdiggykyvswyqqhpgrapkliiydvikrpsgi
sdrfsgsksantasltisglqagdeasyycssyttrayvfgsgtqvtvlgnptvtlfpps
seelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassylslt
peqwkshksyscqvthegstvektvapt