PDB entry 5fuy

View 5fuy on RCSB PDB site
Description: catalytic domain of Thymidine kinase from Trypanosoma brucei with dTMP
Class: transferase
Keywords: transferase, thymidine kinase, t.brucei, tbtk, tkii, dtmp
Deposited on 2016-01-31, released 2016-07-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-11-09, with a file datestamp of 2016-11-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thymdine kinase
    Species: TRYPANOSOMA BRUCEI [TaxId:5691]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q38CF2 (Start-181)
      • engineered mutation (89)
    Domains in SCOPe 2.07: d5fuya1, d5fuya2
  • Chain 'B':
    Compound: thymdine kinase
    Species: TRYPANOSOMA BRUCEI [TaxId:5691]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q38CF2
      • engineered mutation (89)
    Domains in SCOPe 2.07: d5fuyb1, d5fuyb2
  • Chain 'C':
    Compound: thymdine kinase
    Species: TRYPANOSOMA BRUCEI [TaxId:5691]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q38CF2 (Start-181)
      • engineered mutation (89)
    Domains in SCOPe 2.07: d5fuyc1, d5fuyc2
  • Chain 'D':
    Compound: thymdine kinase
    Species: TRYPANOSOMA BRUCEI [TaxId:5691]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q38CF2 (0-End)
      • engineered mutation (89)
    Domains in SCOPe 2.07: d5fuyd1, d5fuyd2
  • Chain 'E':
    Compound: thymdine kinase
    Species: TRYPANOSOMA BRUCEI [TaxId:5691]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q38CF2 (Start-181)
      • expression tag (182)
      • engineered mutation (89)
    Domains in SCOPe 2.07: d5fuye1, d5fuye2, d5fuye3
  • Chain 'F':
    Compound: thymdine kinase
    Species: TRYPANOSOMA BRUCEI [TaxId:5691]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q38CF2 (Start-181)
      • engineered mutation (89)
    Domains in SCOPe 2.07: d5fuyf1, d5fuyf2
  • Heterogens: PO4, QBT, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5fuyA (A:)
ahgrieliigpmfagkttelmrrvqrhkhaqrscyiikytgdtrysegaitshdqralta
nvsvsnlhdvgdewrkydviavdegqffpdvaafcskaadsgkvvivsaldadylqepfe
eicllvsradsvvklsavcmechnrkasftyrtvksderklvggsdmymsvcrscyetkr
nma

    Sequence, based on observed residues (ATOM records): (download) 
    >5fuyA (A:)
hgrieliigpmfagkttelmrrvqrhkhaqrscyiikytaltanvsvsnlhdvgdewrky
dviavdegqffpdvaafcskaadsgkvvivsaldadylqepfeeicllvsradsvvklsa
vcmechnrkasftyrtvksderklvggsdmymsvcrscyetkrnm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5fuyB (B:)
ahgrieliigpmfagkttelmrrvqrhkhaqrscyiikytgdtrysegaitshdqralta
nvsvsnlhdvgdewrkydviavdegqffpdvaafcskaadsgkvvivsaldadylqepfe
eicllvsradsvvklsavcmechnrkasftyrtvksderklvggsdmymsvcrscyetkr
nma

    Sequence, based on observed residues (ATOM records): (download) 
    >5fuyB (B:)
grieliigpmfagkttelmrrvqrhkhaqrscyiikytgdttanvsvsnlhdvgdewrky
dviavdegqffpdvaafcskaadsgkvvivsaldadylqepfeeicllvsradsvvklsa
vcmechnrkasftyrtvksderklvggsdmymsvcrscyetkrn

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5fuyC (C:)
ahgrieliigpmfagkttelmrrvqrhkhaqrscyiikytgdtrysegaitshdqralta
nvsvsnlhdvgdewrkydviavdegqffpdvaafcskaadsgkvvivsaldadylqepfe
eicllvsradsvvklsavcmechnrkasftyrtvksderklvggsdmymsvcrscyetkr
nma

    Sequence, based on observed residues (ATOM records): (download) 
    >5fuyC (C:)
hgrieliigpmfagkttelmrrvqrhkhaqrscyiikytltanvsvsnlhdvgdewrkyd
viavdegqffpdvaafcskaadsgkvvivsaldadylqepfeeicllvsradsvvklsav
cmechnrkasftyrtvksderklvggsdmymsvcrscyetkrnm

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5fuyD (D:)
ahgrieliigpmfagkttelmrrvqrhkhaqrscyiikytgdtrysegaitshdqralta
nvsvsnlhdvgdewrkydviavdegqffpdvaafcskaadsgkvvivsaldadylqepfe
eicllvsradsvvklsavcmechnrkasftyrtvksderklvggsdmymsvcrscyetkr
nma

    Sequence, based on observed residues (ATOM records): (download) 
    >5fuyD (D:)
ahgrieliigpmfagkttelmrrvqrhkhaqrscyiikytanvsvsnlhdvgdewrkydv
iavdegqffpdvaafcskaadsgkvvivsaldadylqepfeeicllvsradsvvklsavc
mechnrkasftyrtvksderklvggsdmymsvcrscyetkr

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5fuyE (E:)
ahgrieliigpmfagkttelmrrvqrhkhaqrscyiikytgdtrysegaitshdqralta
nvsvsnlhdvgdewrkydviavdegqffpdvaafcskaadsgkvvivsaldadylqepfe
eicllvsradsvvklsavcmechnrkasftyrtvksderklvggsdmymsvcrscyetkr
nma

    Sequence, based on observed residues (ATOM records): (download) 
    >5fuyE (E:)
hgrieliigpmfagkttelmrrvqrhkhaqrscyiikytraltanvsvsnlhdvgdewrk
ydviavdegqffpdvaafcskaadsgkvvivsaldadylqepfeeicllvsradsvvkls
avcmechnrkasftyrtvksderklvggsdmymsvcrscyetkrnma

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5fuyF (F:)
ahgrieliigpmfagkttelmrrvqrhkhaqrscyiikytgdtrysegaitshdqralta
nvsvsnlhdvgdewrkydviavdegqffpdvaafcskaadsgkvvivsaldadylqepfe
eicllvsradsvvklsavcmechnrkasftyrtvksderklvggsdmymsvcrscyetkr
nma

    Sequence, based on observed residues (ATOM records): (download) 
    >5fuyF (F:)
hgrieliigpmfagkttelmrrvqrhkhaqrscyiikytgdtrtanvsvsnlhdvgdewr
kydviavdegqffpdvaafcskaadsgkvvivsaldadylqepfeeicllvsradsvvkl
savcmechnrkasftyrtvksderklvggsdmymsvcrscyetkrnm