PDB entry 5by6

View 5by6 on RCSB PDB site
Description: Crystal structure of Trichinella spiralis thymidylate synthase complexed with dUMP
Class: transferase
Keywords: Trichinella spiralis, parasitic nematode, protein-ligand complex, methyltransferase, transferase
Deposited on 2015-06-10, released 2015-06-17
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-06-17, with a file datestamp of 2015-06-12.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Trichinella spiralis [TaxId:6334]
    Gene: ts, Tsp_03568
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5by6a_
  • Chain 'B':
    Compound: Thymidylate synthase
    Species: Trichinella spiralis [TaxId:6334]
    Gene: ts, Tsp_03568
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5by6b_
  • Chain 'C':
    Compound: Thymidylate synthase
    Species: Trichinella spiralis [TaxId:6334]
    Gene: ts, Tsp_03568
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5by6c_
  • Chain 'D':
    Compound: Thymidylate synthase
    Species: Trichinella spiralis [TaxId:6334]
    Gene: ts, Tsp_03568
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5by6d_
  • Heterogens: UMP, DTT, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5by6A (A:)
mtetvhkldtnstsqddyvnqeelnylnqlkdiidhgvrkndrtgigtlstfgtqsrycl
rddifpllttkrvfwrgvveellwfisgstnakqlseknvniwdgnssrefldsrglyny
eegdlgpvygfqwrhfgcpyssmtadykgkgydqlqqcikmireepesrriimtawnpcd
lekvalppchcfvqfyvadgelscqmyqrsadmglgvpfniasyslltrmiahitslkpg
ffihtigdahvylthvdalkvqmerkprpfpklkilrnveniddfraedfelinykpypk
ismpmav

    Sequence, based on observed residues (ATOM records): (download) 
    >5by6A (A:)
dyvnqeelnylnqlkdiidhgvrkndrtgigtlstfgtqsryclrddifpllttkrvfwr
gvveellwfisgstnakqlseknvniwdgnssrefldsrglynyeegdlgpvygfqwrhf
gcpyssmtadykgkgydqlqqcikmireepesrriimtawnpcdlekvalppchcfvqfy
vadgelscqmyqrsadmglgvpfniasyslltrmiahitslkpgffihtigdahvylthv
dalkvqmerkprpfpklkilrnveniddfraedfelinykpypk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5by6B (B:)
mtetvhkldtnstsqddyvnqeelnylnqlkdiidhgvrkndrtgigtlstfgtqsrycl
rddifpllttkrvfwrgvveellwfisgstnakqlseknvniwdgnssrefldsrglyny
eegdlgpvygfqwrhfgcpyssmtadykgkgydqlqqcikmireepesrriimtawnpcd
lekvalppchcfvqfyvadgelscqmyqrsadmglgvpfniasyslltrmiahitslkpg
ffihtigdahvylthvdalkvqmerkprpfpklkilrnveniddfraedfelinykpypk
ismpmav

    Sequence, based on observed residues (ATOM records): (download) 
    >5by6B (B:)
dyvnqeelnylnqlkdiidhgvrkndrtgigtlstfgtqsryclrddifpllttkrvfwr
gvveellwfisgstnakqlseknvniwdgnssrefldsrglynyeegdlgpvygfqwrhf
gcpyssmtadykgkgydqlqqcikmireepesrriimtawnpcdlekvalppchcfvqfy
vadgelscqmyqrsadmglgvpfniasyslltrmiahitslkpgffihtigdahvylthv
dalkvqmerkprpfpklkilrnveniddfraedfelinykpypkismp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5by6C (C:)
mtetvhkldtnstsqddyvnqeelnylnqlkdiidhgvrkndrtgigtlstfgtqsrycl
rddifpllttkrvfwrgvveellwfisgstnakqlseknvniwdgnssrefldsrglyny
eegdlgpvygfqwrhfgcpyssmtadykgkgydqlqqcikmireepesrriimtawnpcd
lekvalppchcfvqfyvadgelscqmyqrsadmglgvpfniasyslltrmiahitslkpg
ffihtigdahvylthvdalkvqmerkprpfpklkilrnveniddfraedfelinykpypk
ismpmav

    Sequence, based on observed residues (ATOM records): (download) 
    >5by6C (C:)
yvnqeelnylnqlkdiidhgvrkndrtgigtlstfgtqsryclrddifpllttkrvfwrg
vveellwfisgstnakqlseknvniwdgnssrefldsrglynyeegdlgpvygfqwrhfg
cpyssmtadykgkgydqlqqcikmireepesrriimtawnpcdlekvalppchcfvqfyv
adgelscqmyqrsadmglgvpfniasyslltrmiahitslkpgffihtigdahvylthvd
alkvqmerkprpfpklkilrnveniddfraedfelinykpypkism

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5by6D (D:)
mtetvhkldtnstsqddyvnqeelnylnqlkdiidhgvrkndrtgigtlstfgtqsrycl
rddifpllttkrvfwrgvveellwfisgstnakqlseknvniwdgnssrefldsrglyny
eegdlgpvygfqwrhfgcpyssmtadykgkgydqlqqcikmireepesrriimtawnpcd
lekvalppchcfvqfyvadgelscqmyqrsadmglgvpfniasyslltrmiahitslkpg
ffihtigdahvylthvdalkvqmerkprpfpklkilrnveniddfraedfelinykpypk
ismpmav

    Sequence, based on observed residues (ATOM records): (download) 
    >5by6D (D:)
yvnqeelnylnqlkdiidhgvrkndrtgigtlstfgtqsryclrddifpllttkrvfwrg
vveellwfisgstnakqlseknvniwdgnssrefldsrglynyeegdlgpvygfqwrhfg
cpyssmtadykgkgydqlqqcikmireepesrriimtawnpcdlekvalppchcfvqfyv
adgelscqmyqrsadmglgvpfniasyslltrmiahitslkpgffihtigdahvylthvd
alkvqmerkprpfpklkilrnveniddfraedfelinykpyp