PDB entry 4pkh

View 4pkh on RCSB PDB site
Description: Complex of ADP-actin With the N-terminal Actin-Binding Domain of Tropomodulin
Class: Contractile Protein/Actin-Binding Protein
Keywords: Tmod, Actin Filament, Pointed-End Capping Protein, Tropomyosin, Contractile Protein, Actin-binding Protein, Contractile Protein-Actin-Binding Protein complex
Deposited on 2014-05-14, released 2014-07-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-25, with a file datestamp of 2019-12-20.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4pkha1, d4pkha2
  • Chain 'B':
    Compound: Gelsolin,Tropomodulin-1 chimera
    Species: Homo sapiens [TaxId:9606]
    Gene: TMOD1, D9S57E, TMOD
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4pkhd1, d4pkhd2
  • Chain 'E':
    Compound: Gelsolin,Tropomodulin-1 chimera
    Species: Homo sapiens [TaxId:9606]
    Gene: TMOD1, D9S57E, TMOD
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4pkhe_
  • Chain 'F':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4pkhf1, d4pkhf2
  • Chain 'G':
    Compound: Gelsolin,Tropomodulin-1 chimera
    Species: Homo sapiens [TaxId:9606]
    Gene: TMOD1, D9S57E, TMOD
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4pkhi1, d4pkhi2
  • Chain 'J':
    Compound: Gelsolin,Tropomodulin-1 chimera
    Species: Homo sapiens [TaxId:9606]
    Gene: TMOD1, D9S57E, TMOD
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4pkhj_
  • Heterogens: ADP, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4pkhA (A:)
mcdedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdea
qskrgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrek
mtqimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrl
dlagrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataasssslek
syelpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannv
msggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwit
kqeydeagpsivhrkcf

    Sequence, based on observed residues (ATOM records): (download) 
    >4pkhA (A:)
ttalvcdngsglvkagfagddapravfpsivgrpdsyvgdeaqskrgiltlkypiehgii
tnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimfetfnvpamyvai
qavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrdltdylmkilter
gysfvttaereivrdikeklcyvaldfenemataassssleksyelpdgqvitignerfr
cpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggttmypgiadrmqke
italapstmkikiiapperkysvwiggsilaslstfqqmwitkqeydeagpsivhrkcf

  • Chain 'B':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4pkhD (D:)
mcdedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdea
qskrgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrek
mtqimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrl
dlagrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataasssslek
syelpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannv
msggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwit
kqeydeagpsivhrkcf

    Sequence, based on observed residues (ATOM records): (download) 
    >4pkhD (D:)
ttalvcdngsglvkagfagddapravfpsivgrprdsyvgdeaqskrgiltlkypiehgi
itnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimfetfnvpamyva
iqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrdltdylmkilte
rgysfvttaereivrdikeklcyvaldfenemataassssleksyelpdgqvitignerf
rcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggttmypgiadrmqk
eitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeydeagpsivhrkcf

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4pkhE (E:)
mvvehpeflkagkepglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqyd
lhywlgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkgg
vasgfggsggsggsqkdqttkaptgpfkreelldhlekqakefkdredlvpytgekrgkv
wvpkqk

    Sequence, based on observed residues (ATOM records): (download) 
    >4pkhE (E:)
vvehpeflkagkepglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqydl
hywlgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkggv
asgfg

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4pkhF (F:)
mcdedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdea
qskrgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrek
mtqimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrl
dlagrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataasssslek
syelpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannv
msggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwit
kqeydeagpsivhrkcf

    Sequence, based on observed residues (ATOM records): (download) 
    >4pkhF (F:)
ttalvcdngsglvkagfagddapravfpsivgrprhqgvmvsyvgdeaqskrgiltlkyp
iehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimfetfnvp
amyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrdltdylm
kiltergysfvttaereivrdikeklcyvaldfenemataassssleksyelpdgqviti
gnerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggttmypgia
drmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeydeagpsiv
hrkcf

  • Chain 'G':
    No sequence available.

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >4pkhI (I:)
mcdedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdea
qskrgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrek
mtqimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrl
dlagrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataasssslek
syelpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannv
msggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwit
kqeydeagpsivhrkcf

    Sequence, based on observed residues (ATOM records): (download) 
    >4pkhI (I:)
ttalvcdngsglvkagfagddapravfpsivgrprdsyvgdeaqskrgiltlkypiehgi
itnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimfetfnvpamyva
iqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrdltdylmkilte
rgysfvttaereivrdikeklcyvaldfenemataassssleksyelpdgqvitignerf
rcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggttmypgiadrmqk
eitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeydeagpsivhrkcf

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >4pkhJ (J:)
mvvehpeflkagkepglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqyd
lhywlgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkgg
vasgfggsggsggsqkdqttkaptgpfkreelldhlekqakefkdredlvpytgekrgkv
wvpkqk

    Sequence, based on observed residues (ATOM records): (download) 
    >4pkhJ (J:)
mvvehpeflkagkepglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqyd
lhywlgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkgg
vasgfg