SCOPe 2.08: Domain d1moxa3: 1mox A:163-311

Lineage for d1moxa3 (1mox A:163-311)

1. Root: SCOPe 2.08

2. Class g: Small proteins [56992] (100 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.9: Growth factor receptor domain [57184] (2 families)

5. Family g.3.9.1: Growth factor receptor domain [57185] (11 proteins)
   Pfam PF00757; Pfam PF14843; Pfam PF15913
   heterogeneous fold; applies to domains that adopt a different fold than the exemplar domain but has similar sequence and number of secondary structures
   

6. Protein EGF receptor Cys-rich domains, N-terminal domain [419056] (1 species)
7. Species Human (Homo sapiens) [TaxId:9606] [419547] (4 PDB entries)

8. Domain d1moxa3: 1mox A:163-311 [91374]
   Other proteins in same PDB: d1moxa1, d1moxa2, d1moxa4, d1moxb1, d1moxb2, d1moxb4, d1moxc_, d1moxd_
   complexed with TGF-alpha
   complexed with cd, cl, nag, pt

Details for d1moxa3

PDB Entry: 1mox, 2.5 Å

PDB Description: crystal structure of human epidermal growth factor receptor (residues 1-501) in complex with tgf-alpha

PDB Compounds: (A:) Epidermal growth factor receptor

SCOPe Domain Sequences for d1moxa3:

Sequence, based on SEQRES records:

>d1moxa3 g.3.9.1 (A:163-311) EGF receptor Cys-rich domains, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
cqkcdpscpngscwgageencqkltkiicaqqcsgrcrgkspsdcchnqcaagctgpres
dclvcrkfrdeatckdtcpplmlynpttyqmdvnpegkysfgatcvkkcprnyvvtdhgs
cvracgadsyemeedgvrkckkcegpcrk

Sequence, based on observed residues (ATOM records):

>d1moxa3 g.3.9.1 (A:163-311) EGF receptor Cys-rich domains, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
cqkcdpscpngscwgageencqkltkiicaqqcsgrcrgkspsdcchnqcaagctgpres
dclvcrkfrdeatckdtcpplmlynpttyqmdvnpegkysfgatcvkkcprnyvvtdhgs
cvracgadsyemeedgvrkckkcgpcrk

Timeline for d1moxa3:

• d1moxa3 first appeared in SCOP 1.67
  
• d1moxa3 appears in SCOPe 2.07