Lineage for Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module

  1. Root: SCOPe 2.02
  2. 1143363Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1162387Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 1162388Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 1162663Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module [88749] (8 proteins)
    the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology

Proteins:

  1. 1162664Acetohydroxyacid synthase catalytic subunit [88758] (2 species)
    1. 1162665Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88759] (6 PDB entries)
      Uniprot P07342 84-687
    2. 1162680Species Thale cress (Arabidopsis thaliana), chloroplast [TaxId:3702] [142208] (6 PDB entries)
      Uniprot P17597 460-667
  2. 1162687Benzoylformate decarboxylase [88756] (1 species)
  3. 1162716Carboxyethylarginine synthase [102335] (1 species)
  4. 1162740Catabolic acetolactate synthase [102333] (1 species)
  5. 1162750Indole-3-pyruvate decarboxylase [89654] (1 species)
  6. 1162756Oxalyl-CoA decarboxylase [142209] (1 species)
  7. 1162770Pyruvate decarboxylase [88750] (3 species)
    1. 1162771Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88752] (2 PDB entries)
    2. 1162776Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] [88751] (1 PDB entry)
    3. 1162779Species Zymomonas mobilis [TaxId:542] [88753] (1 PDB entry)
  8. 1162784Pyruvate oxidase [88754] (2 species)
    1. 1162785Species Aerococcus viridans [TaxId:1377] [142207] (4 PDB entries)
    2. 1162790Species Lactobacillus plantarum [TaxId:1590] [88755] (7 PDB entries)

More info for Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module

Timeline for Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module: