Lineage for Protein: Pyruvate oxidase

  1. Root: SCOPe 2.02
  2. 1143363Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1162387Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 1162388Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 1162663Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module [88749] (8 proteins)
    the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology
  6. 1162784Protein Pyruvate oxidase [88754] (2 species)

Species:

  1. 1162785Aerococcus viridans [TaxId:1377] [142207] (4 PDB entries)
    1. Domain for 1v5e:
    2. Domain for 1v5f:
    3. Domain for 1v5g:
    4. Domain for 2dji:
  2. 1162790Lactobacillus plantarum [TaxId:1590] [88755] (7 PDB entries)
    1. Domains for 1pow:
      1. 1162803Domain d1powa3: 1pow A:366-593 [31798]
        Other proteins in same PDB: d1powa1, d1powa2, d1powb1, d1powb2
        complexed with fad, mg, tpp; mutant
      2. 1162804Domain d1powb3: 1pow B:366-593 [31800]
        Other proteins in same PDB: d1powa1, d1powa2, d1powb1, d1powb2
        complexed with fad, mg, tpp; mutant
    2. Domains for 1pox:
      1. 1162797Domain d1poxa3: 1pox A:366-593 [31794]
        Other proteins in same PDB: d1poxa1, d1poxa2, d1poxb1, d1poxb2
        complexed with fad, gol, mg, na, tpp; mutant
      2. 1162798Domain d1poxb3: 1pox B:366-593 [31796]
        Other proteins in same PDB: d1poxa1, d1poxa2, d1poxb1, d1poxb2
        complexed with fad, gol, mg, na, tpp; mutant
    3. Domains for 2ez4:
      1. 1162795Domain d2ez4a3: 2ez4 A:366-593 [132612]
        Other proteins in same PDB: d2ez4a1, d2ez4a2, d2ez4b1, d2ez4b2
        automatically matched to d1powa3
        complexed with fad, mg, na, po4, tpp
      2. 1162796Domain d2ez4b3: 2ez4 B:366-593 [132615]
        Other proteins in same PDB: d2ez4a1, d2ez4a2, d2ez4b1, d2ez4b2
        automatically matched to d1powa3
        complexed with fad, mg, na, po4, tpp
    4. Domains for 2ez8:
      1. 1162793Domain d2ez8a3: 2ez8 A:366-593 [132623]
        Other proteins in same PDB: d2ez8a1, d2ez8a2, d2ez8b1, d2ez8b2
        automatically matched to d1powa3
        complexed with fad, mg, na, pyr, tdl
      2. 1162794Domain d2ez8b3: 2ez8 B:366-593 [132626]
        Other proteins in same PDB: d2ez8a1, d2ez8a2, d2ez8b1, d2ez8b2
        automatically matched to d1powa3
        complexed with fad, mg, na, pyr, tdl
    5. Domains for 2ez9:
      1. 1162791Domain d2ez9a3: 2ez9 A:366-593 [132629]
        Other proteins in same PDB: d2ez9a1, d2ez9a2, d2ez9b1, d2ez9b2
        automatically matched to d1powa3
        complexed with fad, mg, na, tdk
      2. 1162792Domain d2ez9b3: 2ez9 B:366-593 [132632]
        Other proteins in same PDB: d2ez9a1, d2ez9a2, d2ez9b1, d2ez9b2
        automatically matched to d1powa3
        complexed with fad, mg, na, tdk
    6. Domains for 2ezt:
      1. 1162801Domain d2ezta3: 2ezt A:366-593 [132635]
        Other proteins in same PDB: d2ezta1, d2ezta2, d2eztb1, d2eztb2
        automatically matched to d1powa3
        complexed with fad, mg, na, po4, pyr, tdm
      2. 1162802Domain d2eztb3: 2ezt B:366-593 [132638]
        Other proteins in same PDB: d2ezta1, d2ezta2, d2eztb1, d2eztb2
        automatically matched to d1powa3
        complexed with fad, mg, na, po4, pyr, tdm
    7. Domains for 2ezu:
      1. 1162799Domain d2ezua3: 2ezu A:366-593 [132641]
        Other proteins in same PDB: d2ezua1, d2ezua2, d2ezub1, d2ezub2
        automatically matched to d1powa3
        complexed with fad, htl, mg, na, pyr
      2. 1162800Domain d2ezub3: 2ezu B:366-593 [132644]
        Other proteins in same PDB: d2ezua1, d2ezua2, d2ezub1, d2ezub2
        automatically matched to d1powa3
        complexed with fad, htl, mg, na, pyr

More info for Protein Pyruvate oxidase from c.36.1.9: Pyruvate oxidase and decarboxylase PP module

Timeline for Protein Pyruvate oxidase from c.36.1.9: Pyruvate oxidase and decarboxylase PP module: