Lineage for d1jscb2 (1jsc B:82-272)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2108258Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 2108259Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 2108260Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module [88724] (8 protein domains)
    the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpha/beta domain of Rossmann-like topology
    automatically mapped to Pfam PF02776
  6. 2108261Protein Acetohydroxyacid synthase catalytic subunit [88733] (3 species)
  7. 2108262Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88734] (6 PDB entries)
    Uniprot P07342 84-687
  8. 2108274Domain d1jscb2: 1jsc B:82-272 [67228]
    Other proteins in same PDB: d1jsca1, d1jsca3, d1jscb1, d1jscb3
    complexed with 2hp, fad, k, mg, tpp

Details for d1jscb2

PDB Entry: 1jsc (more details), 2.6 Å

PDB Description: Crystal Structure of the Catalytic Subunit of Yeast Acetohydroxyacid Synthase: A target for Herbicidal Inhibitors
PDB Compounds: (B:) acetohydroxy-acid synthase

SCOPe Domain Sequences for d1jscb2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1jscb2 c.36.1.5 (B:82-272) Acetohydroxyacid synthase catalytic subunit {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}

SCOPe Domain Coordinates for d1jscb2:

Click to download the PDB-style file with coordinates for d1jscb2.
(The format of our PDB-style files is described here.)

Timeline for d1jscb2: