Lineage for Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2108258Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 2108259Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 2108260Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module [88724] (8 protein domains)
    the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpha/beta domain of Rossmann-like topology
    automatically mapped to Pfam PF02776

Protein Domains:

  1. 2108261Acetohydroxyacid synthase catalytic subunit [88733] (3 species)
    1. 2108262Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88734] (10 PDB entries)
      Uniprot P07342 84-687
    2. 2108277Species Thale cress (Arabidopsis thaliana), chloroplast [TaxId:3702] [142204] (11 PDB entries)
      Uniprot P17597 86-280
    3. 2270801Species Saccharomyces cerevisiae [TaxId:559292] [314106] (2 PDB entries)
  2. 2108284Benzoylformate decarboxylase [88731] (1 species)
  3. 2108308Carboxyethylarginine synthase [102330] (1 species)
  4. 2108336Catabolic acetolactate synthase [102328] (1 species)
  5. 2108346Indole-3-pyruvate decarboxylase [89648] (1 species)
  6. 2108352Oxalyl-CoA decarboxylase [142205] (1 species)
  7. 2108366Pyruvate decarboxylase [88725] (3 species)
    1. 2108367Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88727] (2 PDB entries)
    2. 2108372Species Brewer's yeast (Saccharomyces uvarum) [TaxId:230603] [88726] (1 PDB entry)
    3. 2108375Species Zymomonas mobilis [TaxId:542] [88728] (1 PDB entry)
  8. 2108380Pyruvate oxidase [88729] (2 species)
    1. 2108381Species Aerococcus viridans [TaxId:1377] [142203] (2 PDB entries)
    2. Species Lactobacillus plantarum [TaxId:1590] [88730] (2 PDB entries)

More info for Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module

Timeline for Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module: