Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465 |
Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules |
Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module [88724] (8 proteins) the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpha/beta domain of Rossmann-like topology automatically mapped to Pfam PF02776 |
Protein Acetohydroxyacid synthase catalytic subunit [88733] (3 species) |
Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88734] (8 PDB entries) Uniprot P07342 84-687 |
Domain d1jsca2: 1jsc A:83-270 [67225] Other proteins in same PDB: d1jsca1, d1jsca3, d1jscb1, d1jscb3 complexed with 2hp, fad, k, mg, tpp |
Domain d1jscb2: 1jsc B:82-272 [67228] Other proteins in same PDB: d1jsca1, d1jsca3, d1jscb1, d1jscb3 complexed with 2hp, fad, k, mg, tpp |
Domain d1n0ha2: 1n0h A:83-270 [79735] Other proteins in same PDB: d1n0ha1, d1n0ha3, d1n0hb1, d1n0hb3 complexed with ayd, cie, dtt, fad, k, mg, tpp |
Domain d1n0hb2: 1n0h B:83-270 [79738] Other proteins in same PDB: d1n0ha1, d1n0ha3, d1n0hb1, d1n0hb3 complexed with ayd, cie, dtt, fad, k, mg, tpp |
Domain d1t9aa2: 1t9a A:89-263 [112329] Other proteins in same PDB: d1t9aa1, d1t9aa3, d1t9ab1, d1t9ab3 complexed with 1tb, fad, k, mg, p23, yf3, yf4 |
Domain d1t9ab2: 1t9a B:89-263 [112332] Other proteins in same PDB: d1t9aa1, d1t9aa3, d1t9ab1, d1t9ab3 complexed with 1tb, fad, k, mg, p23, yf3, yf4 |
Domain d1t9ba2: 1t9b A:89-263 [112335] Other proteins in same PDB: d1t9ba1, d1t9ba3, d1t9bb1, d1t9bb3 complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3 |
Domain d1t9bb2: 1t9b B:89-263 [112338] Other proteins in same PDB: d1t9ba1, d1t9ba3, d1t9bb1, d1t9bb3 complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3 |
Domain d1t9ca2: 1t9c A:89-263 [112341] Other proteins in same PDB: d1t9ca1, d1t9ca3, d1t9cb1, d1t9cb3 complexed with 1sm, fad, k, mg, p22, p23 |
Domain d1t9cb2: 1t9c B:89-263 [112344] Other proteins in same PDB: d1t9ca1, d1t9ca3, d1t9cb1, d1t9cb3 complexed with 1sm, fad, k, mg, p22, p23 |
Domain d1t9da2: 1t9d A:89-263 [112347] Other proteins in same PDB: d1t9da1, d1t9da3, d1t9db1, d1t9db3, d1t9dc1, d1t9dc3, d1t9dd1, d1t9dd3 complexed with 1mm, fad, k, mg, p22, p25, pyd |
Domain d1t9db2: 1t9d B:89-263 [112350] Other proteins in same PDB: d1t9da1, d1t9da3, d1t9db1, d1t9db3, d1t9dc1, d1t9dc3, d1t9dd1, d1t9dd3 complexed with 1mm, fad, k, mg, p22, p25, pyd |
Domain d1t9dc2: 1t9d C:89-263 [112353] Other proteins in same PDB: d1t9da1, d1t9da3, d1t9db1, d1t9db3, d1t9dc1, d1t9dc3, d1t9dd1, d1t9dd3 complexed with 1mm, fad, k, mg, p22, p25, pyd |
Domain d1t9dd2: 1t9d D:89-263 [112356] Other proteins in same PDB: d1t9da1, d1t9da3, d1t9db1, d1t9db3, d1t9dc1, d1t9dc3, d1t9dd1, d1t9dd3 complexed with 1mm, fad, k, mg, p22, p25, pyd |
Domain d6bd3a1: 6bd3 A:83-270 [341189] Other proteins in same PDB: d6bd3a2, d6bd3a3, d6bd3b2, d6bd3b3 automated match to d1n0ha2 complexed with act, co2, fad, htl, k, mg, oxy, po4, tpp |
Domain d6bd3b1: 6bd3 B:84-270 [341191] Other proteins in same PDB: d6bd3a2, d6bd3a3, d6bd3b2, d6bd3b3 automated match to d1n0ha2 complexed with act, co2, fad, htl, k, mg, oxy, po4, tpp |
Domain d6bd9a1: 6bd9 A:83-271 [341294] Other proteins in same PDB: d6bd9a2, d6bd9a3, d6bd9b2, d6bd9b3 automated match to d1n0ha2 complexed with fad, k, mg, oxy, po4, pyr, tpp |
Domain d6bd9b1: 6bd9 B:83-270 [341350] Other proteins in same PDB: d6bd9a2, d6bd9a3, d6bd9b2, d6bd9b3 automated match to d1n0ha2 complexed with fad, k, mg, oxy, po4, pyr, tpp |
Timeline for Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] from c.36.1.5 Acetohydroxyacid synthase catalytic subunit: