Lineage for Protein: Acetohydroxyacid synthase catalytic subunit

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2445862Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 2445863Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 2445864Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module [88724] (8 protein domains)
    the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpha/beta domain of Rossmann-like topology
    automatically mapped to Pfam PF02776
  6. 2445865Protein Acetohydroxyacid synthase catalytic subunit [88733] (3 species)

Species:

  1. 2445866Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88734] (8 PDB entries)
    Uniprot P07342 84-687
    1. Domains for 1jsc:
      1. 2445867Domain d1jsca2: 1jsc A:83-270 [67225]
        Other proteins in same PDB: d1jsca1, d1jsca3, d1jscb1, d1jscb3
        complexed with 2hp, fad, k, mg, tpp
      2. 2445868Domain d1jscb2: 1jsc B:82-272 [67228]
        Other proteins in same PDB: d1jsca1, d1jsca3, d1jscb1, d1jscb3
        complexed with 2hp, fad, k, mg, tpp
    2. Domains for 1n0h:
      1. 2445883Domain d1n0ha2: 1n0h A:83-270 [79735]
        Other proteins in same PDB: d1n0ha1, d1n0ha3, d1n0hb1, d1n0hb3
        complexed with ayd, cie, dtt, fad, k, mg, tpp
      2. 2445884Domain d1n0hb2: 1n0h B:83-270 [79738]
        Other proteins in same PDB: d1n0ha1, d1n0ha3, d1n0hb1, d1n0hb3
        complexed with ayd, cie, dtt, fad, k, mg, tpp
    3. Domains for 1t9a:
      1. 2445881Domain d1t9aa2: 1t9a A:89-263 [112329]
        Other proteins in same PDB: d1t9aa1, d1t9aa3, d1t9ab1, d1t9ab3
        complexed with 1tb, fad, k, mg, p23, yf3, yf4
      2. 2445882Domain d1t9ab2: 1t9a B:89-263 [112332]
        Other proteins in same PDB: d1t9aa1, d1t9aa3, d1t9ab1, d1t9ab3
        complexed with 1tb, fad, k, mg, p23, yf3, yf4
    4. Domains for 1t9b:
      1. 2445871Domain d1t9ba2: 1t9b A:89-263 [112335]
        Other proteins in same PDB: d1t9ba1, d1t9ba3, d1t9bb1, d1t9bb3
        complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3
      2. 2445872Domain d1t9bb2: 1t9b B:89-263 [112338]
        Other proteins in same PDB: d1t9ba1, d1t9ba3, d1t9bb1, d1t9bb3
        complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3
    5. Domains for 1t9c:
      1. 2445879Domain d1t9ca2: 1t9c A:89-263 [112341]
        Other proteins in same PDB: d1t9ca1, d1t9ca3, d1t9cb1, d1t9cb3
        complexed with 1sm, fad, k, mg, p22, p23
      2. 2445880Domain d1t9cb2: 1t9c B:89-263 [112344]
        Other proteins in same PDB: d1t9ca1, d1t9ca3, d1t9cb1, d1t9cb3
        complexed with 1sm, fad, k, mg, p22, p23
    6. Domains for 1t9d:
      1. 2445875Domain d1t9da2: 1t9d A:89-263 [112347]
        Other proteins in same PDB: d1t9da1, d1t9da3, d1t9db1, d1t9db3, d1t9dc1, d1t9dc3, d1t9dd1, d1t9dd3
        complexed with 1mm, fad, k, mg, p22, p25, pyd
      2. 2445876Domain d1t9db2: 1t9d B:89-263 [112350]
        Other proteins in same PDB: d1t9da1, d1t9da3, d1t9db1, d1t9db3, d1t9dc1, d1t9dc3, d1t9dd1, d1t9dd3
        complexed with 1mm, fad, k, mg, p22, p25, pyd
      3. 2445877Domain d1t9dc2: 1t9d C:89-263 [112353]
        Other proteins in same PDB: d1t9da1, d1t9da3, d1t9db1, d1t9db3, d1t9dc1, d1t9dc3, d1t9dd1, d1t9dd3
        complexed with 1mm, fad, k, mg, p22, p25, pyd
      4. 2445878Domain d1t9dd2: 1t9d D:89-263 [112356]
        Other proteins in same PDB: d1t9da1, d1t9da3, d1t9db1, d1t9db3, d1t9dc1, d1t9dc3, d1t9dd1, d1t9dd3
        complexed with 1mm, fad, k, mg, p22, p25, pyd
    7. Domains for 6bd3:
      1. 2445873Domain d6bd3a1: 6bd3 A:83-270 [341189]
        Other proteins in same PDB: d6bd3a2, d6bd3a3, d6bd3b2, d6bd3b3
        automated match to d1n0ha2
        complexed with act, co2, fad, htl, k, mg, oxy, po4, tpp
      2. 2445874Domain d6bd3b1: 6bd3 B:84-270 [341191]
        Other proteins in same PDB: d6bd3a2, d6bd3a3, d6bd3b2, d6bd3b3
        automated match to d1n0ha2
        complexed with act, co2, fad, htl, k, mg, oxy, po4, tpp
    8. Domains for 6bd9:
      1. 2445869Domain d6bd9a1: 6bd9 A:83-271 [341294]
        Other proteins in same PDB: d6bd9a2, d6bd9a3, d6bd9b2, d6bd9b3
        automated match to d1n0ha2
        complexed with fad, k, mg, oxy, po4, pyr, tpp
      2. 2445870Domain d6bd9b1: 6bd9 B:83-270 [341350]
        Other proteins in same PDB: d6bd9a2, d6bd9a3, d6bd9b2, d6bd9b3
        automated match to d1n0ha2
        complexed with fad, k, mg, oxy, po4, pyr, tpp
  2. 2445885Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [314106] (3 PDB entries)
    1. Domains for 5fem:
      1. 2445888Domain d5fema1: 5fem A:83-270 [314121]
        Other proteins in same PDB: d5fema2, d5fema3, d5femb2, d5femb3
        automated match to d1n0ha2
        complexed with 60g, fad, mg, tpp
      2. 2445889Domain d5femb1: 5fem B:83-270 [314107]
        Other proteins in same PDB: d5fema2, d5fema3, d5femb2, d5femb3
        automated match to d1n0ha2
        complexed with 60g, fad, mg, tpp
    2. Domains for 5ims:
      1. 2445886Domain d5imsa1: 5ims A:83-271 [329726]
        Other proteins in same PDB: d5imsa2, d5imsa3, d5imsb2, d5imsb3
        automated match to d1n0ha2
        complexed with act, fad, k, mg, oxy, po4, tpp
      2. 2445887Domain d5imsb1: 5ims B:83-270 [329799]
        Other proteins in same PDB: d5imsa2, d5imsa3, d5imsb2, d5imsb3
        automated match to d1n0ha2
        complexed with act, fad, k, mg, oxy, po4, tpp
    3. Domains for 5wkc:
      1. 3048134Domain d5wkca1: 5wkc A:85-267 [348196]
        Other proteins in same PDB: d5wkca2, d5wkca3, d5wkcb2, d5wkcb3, d5wkcd2, d5wkcd3, d5wkce2, d5wkce3
        automated match to d1n0ha2
        complexed with auj, f50, fad, mg, pxd, tp9
      2. 3048154Domain d5wkcd1: 5wkc D:84-269 [348216]
        Other proteins in same PDB: d5wkca2, d5wkca3, d5wkcb2, d5wkcb3, d5wkcd2, d5wkcd3, d5wkce2, d5wkce3
        automated match to d1n0ha2
        complexed with auj, f50, fad, mg, pxd, tp9
      3. 3048240Domain d5wkce1: 5wkc E:84-269 [348302]
        Other proteins in same PDB: d5wkca2, d5wkca3, d5wkcb2, d5wkcb3, d5wkcd2, d5wkcd3, d5wkce2, d5wkce3
        automated match to d1n0ha2
        complexed with auj, f50, fad, mg, pxd, tp9
      4. 3048283Domain d5wkcb1: 5wkc B:83-269 [348346]
        Other proteins in same PDB: d5wkca2, d5wkca3, d5wkcb2, d5wkcb3, d5wkcd2, d5wkcd3, d5wkce2, d5wkce3
        automated match to d1n0ha2
        complexed with auj, f50, fad, mg, pxd, tp9
  3. 2445890Thale cress (Arabidopsis thaliana), chloroplast [TaxId:3702] [142204] (12 PDB entries)
    Uniprot P17597 86-280
    1. Domain for 1ybh:
    2. Domain for 1yhy:
    3. Domain for 1yhz:
    4. Domain for 1yi0:
    5. Domain for 1yi1:
    6. Domain for 1z8n:
    7. Domain for 5k2o:
    8. Domain for 5k3s:
    9. Domain for 5k6q:
    10. Domain for 5k6r:
    11. Domain for 5k6t:
    12. Domain for 5wj1:

More info for Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module

Timeline for Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module:

  • Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module first appeared in SCOP 1.65
  • Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module appears in SCOPe 2.06