Lineage for Family c.37.1.1: Nucleotide and nucleoside kinases

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2109203Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2109204Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2109205Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 protein domains)
    parallel beta-sheet of 5 strands, order 23145

Protein Domains:

  1. 21092065' polynucleotide kinase-3' phosphatase, C-terminal domain [142213] (1 species)
  2. 2109210Adenylate kinase [52554] (16 species)
    1. 2109211Species Bacillus globisporus [TaxId:1459] [102342] (1 PDB entry)
      contains a zinc-finger subdomain, residues 126-160
    2. 2109213Species Bacillus stearothermophilus [TaxId:1422] [52562] (3 PDB entries)
      contains a zinc-finger subdomain, residues 126-160
    3. 2109217Species Bacillus subtilis [TaxId:1423] [102341] (1 PDB entry)
      contains a zinc-finger subdomain, residues 126-160
    4. 2109219Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52559] (4 PDB entries)
      contains a rudiment "zinc-finger" subdomain, residue 131-168
    5. 2109225Species Cow (Bos taurus), mitochondrial izozyme-2 [TaxId:9913] [52558] (2 PDB entries)
      contains a rudiment "zinc-finger" subdomain, residue 147-176
    6. 2109228Species Cow (Bos taurus), mitochondrial izozyme-3 [TaxId:9913] [52557] (1 PDB entry)
      contains a rudiment "zinc-finger" subdomain, residue 125-161
    7. 2109231Species Escherichia coli [TaxId:1133853] [256826] (1 PDB entry)
    8. 2109234Species Escherichia coli [TaxId:562] [52560] (8 PDB entries)
      contains a rudiment "zinc-finger" subdomain, residue 122-156
    9. 2109251Species Human (Homo sapiens), isoenzyme 6 [TaxId:9606] [117527] (1 PDB entry)
      Uniprot Q9Y3D8
    10. 2109253Species Maize (Zea mays) [TaxId:4577] [52561] (1 PDB entry)
    11. 2109256Species Methanococcus thermolithotrophicus [TaxId:2186] [89661] (1 PDB entry)
    12. 2109260Species Methanococcus voltae [TaxId:2188] [89660] (1 PDB entry)
    13. 2109264Species Mycobacterium tuberculosis [TaxId:1773] [102343] (2 PDB entries)
      contains no zinc finger-like insertion
    14. 2109267Species Pig (Sus scrofa) [TaxId:9823] [52555] (1 PDB entry)
    15. 2109269Species Sulfolobus acidocaldarius [TaxId:2285] [52556] (1 PDB entry)
    16. 2109276Species Thermus thermophilus [TaxId:274] [188607] (1 PDB entry)
  3. 2109278CMP kinase [52548] (3 species)
    1. 2109279Species Escherichia coli [TaxId:562] [52549] (6 PDB entries)
    2. 2109290Species Pneumococcus (Streptococcus pneumoniae) [TaxId:1313] [110525] (1 PDB entry)
      Uniprot Q97PK6
    3. 2109292Species Staphylococcus aureus [TaxId:1280] [187794] (1 PDB entry)
  4. 2109296Deoxycytidine kinase [89657] (1 species)
  5. 2109394Deoxyguanosine kinase [69480] (1 species)
  6. 2109412Deoxynucleoside monophosphate kinase [52546] (1 species)
    contains insert 4-helical bundle subdomain, residues 35-145
  7. 2109418Deoxyribonucleoside kinase [69478] (1 species)
  8. 2109462Dephospho-CoA kinase [75187] (4 species)
    1. 2109463Species Escherichia coli [TaxId:562] [82394] (5 PDB entries)
    2. 2109479Species Haemophilus influenzae [TaxId:727] [75188] (1 PDB entry)
    3. 2109481Species Thermotoga maritima [TaxId:2336] [187766] (1 PDB entry)
    4. 2109490Species Thermus thermophilus [TaxId:274] [102344] (1 PDB entry)
      TT1252
  9. 2109494Guanylate kinase [52542] (5 species)
    1. 2109495Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52543] (6 PDB entries)
    2. 2109507Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [189750] (1 PDB entry)
    3. 2109510Species Escherichia coli [TaxId:562] [102338] (6 PDB entries)
    4. 2109530Species Mouse (Mus musculus) [TaxId:10090] [82393] (1 PDB entry)
    5. 2109532Species Mycobacterium tuberculosis [TaxId:1773] [102339] (2 PDB entries)
      Rv1389
  10. 2109535Guanylate kinase-like domain of Cask [69474] (1 species)
  11. 2109538Guanylate kinase-like domain of Psd-95 [69476] (1 species)
  12. 2109544Guanylate kinase-like domain of the L-type calcium channel [110527] (2 species)
    1. 2109545Species Norway rat (Rattus norvegicus) [TaxId:10116] [110529] (5 PDB entries)
      Uniprot P54287 38-362
    2. 2109554Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [110528] (4 PDB entries)
      Uniprot P54288 234-451
  13. 2109559Hypothetical protein YorR [142211] (1 species)
  14. 2109563Polynucleotide kinase, kinase domain [75191] (1 species)
  15. 2109582Probable kinase LmjF30.1890 [117528] (1 species)
  16. 2109585Thymidine kinase [52552] (4 species)
    contains insert all-alpha subdomain, res. 251-322
    1. 2109586Species Equine herpesvirus type 4 [TaxId:10331] [102340] (4 PDB entries)
    2. 2109599Species Herpes simplex virus type 1, different strains [TaxId:10298] [52553] (33 PDB entries)
      Uniprot P03176 46-375
    3. 2109663Species Herpes simplex virus type i [311159] (1 PDB entry)
    4. 2109665Species Varicella-Zoster virus [TaxId:10335] [89659] (1 PDB entry)
  17. 2109670Thymidylate kinase [52563] (4 species)
    1. 2109671Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52564] (3 PDB entries)
    2. 2109684Species Escherichia coli [TaxId:562] [52565] (2 PDB entries)
    3. 2109687Species Human (Homo sapiens) [TaxId:9606] [64010] (20 PDB entries)
    4. 2109708Species Mycobacterium tuberculosis [TaxId:1773] [69482] (9 PDB entries)
  18. 2109721Transcriptional regulator NadR, ribosylnicotinamide kinase domain [75189] (1 species)
  19. 2109724UMP/CMP kinase [52550] (2 species)
    1. 2109725Species Human (Homo sapiens) [TaxId:9606] [110526] (1 PDB entry)
      Uniprot P30085
    2. 2109727Species Slime mold (Dictyostelium discoideum) [TaxId:44689] [52551] (6 PDB entries)
  20. 2109734Uridylate kinase [52544] (1 species)
  21. 2109738automated matches [190087] (10 species)
    not a true protein
    1. 2109739Species Bacillus subtilis [TaxId:1423] [189093] (1 PDB entry)
    2. 2109742Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [311340] (1 PDB entry)
    3. 2109745Species Escherichia coli [TaxId:562] [187701] (2 PDB entries)
    4. 2109748Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [233748] (5 PDB entries)
    5. 2109772Species Herpes simplex virus type i [311158] (1 PDB entry)
    6. 2109775Species Human (Homo sapiens) [TaxId:9606] [187523] (7 PDB entries)
    7. 2109786Species Methanococcus maripaludis [TaxId:39152] [189067] (1 PDB entry)
    8. 2109791Species Mycobacterium tuberculosis [TaxId:1773] [186809] (11 PDB entries)
    9. 2109809Species Vibrio cholerae [TaxId:243277] [225848] (2 PDB entries)
    10. 2109813Species Yersinia pseudotuberculosis [TaxId:502800] [226541] (1 PDB entry)

More info for Family c.37.1.1: Nucleotide and nucleoside kinases

Timeline for Family c.37.1.1: Nucleotide and nucleoside kinases: