Lineage for Family c.37.1.1: Nucleotide and nucleoside kinases

  1. Root: SCOPe 2.08
  2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families) (S)
    division into families based on beta-sheet topologies
  5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 proteins)
    parallel beta-sheet of 5 strands, order 23145

Proteins:

  1. 5' polynucleotide kinase-3' phosphatase, C-terminal domain [142213] (1 species)
  2. Adenylate kinase [52554] (16 species)
    1. Species Bacillus globisporus [TaxId:1459] [102342] (1 PDB entry)
      contains a zinc-finger subdomain, residues 126-160
    2. Species Bacillus stearothermophilus [TaxId:1422] [52562] (3 PDB entries)
      contains a zinc-finger subdomain, residues 126-160
    3. Species Bacillus subtilis [TaxId:1423] [102341] (1 PDB entry)
      contains a zinc-finger subdomain, residues 126-160
    4. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52559] (4 PDB entries)
      contains a rudiment "zinc-finger" subdomain, residue 131-168
    5. Species Cow (Bos taurus), mitochondrial izozyme-2 [TaxId:9913] [52558] (2 PDB entries)
      contains a rudiment "zinc-finger" subdomain, residue 147-176
    6. Species Cow (Bos taurus), mitochondrial izozyme-3 [TaxId:9913] [52557] (1 PDB entry)
      contains a rudiment "zinc-finger" subdomain, residue 125-161
    7. Species Escherichia coli [TaxId:1133853] [256826] (1 PDB entry)
    8. Species Escherichia coli [TaxId:562] [52560] (9 PDB entries)
      contains a rudiment "zinc-finger" subdomain, residue 122-156
    9. Species Human (Homo sapiens), isoenzyme 6 [TaxId:9606] [117527] (1 PDB entry)
      Uniprot Q9Y3D8
    10. Species Maize (Zea mays) [TaxId:4577] [52561] (1 PDB entry)
    11. Species Methanococcus thermolithotrophicus [TaxId:2186] [89661] (2 PDB entries)
    12. Species Methanococcus voltae [TaxId:2188] [89660] (1 PDB entry)
    13. Species Mycobacterium tuberculosis [TaxId:1773] [102343] (2 PDB entries)
      contains no zinc finger-like insertion
    14. Species Pig (Sus scrofa) [TaxId:9823] [52555] (1 PDB entry)
    15. Species Sulfolobus acidocaldarius [TaxId:2285] [52556] (1 PDB entry)
    16. Species Thermus thermophilus [TaxId:274] [188607] (1 PDB entry)
  3. CMP kinase [52548] (3 species)
    1. Species Escherichia coli [TaxId:562] [52549] (6 PDB entries)
    2. Species Pneumococcus (Streptococcus pneumoniae) [TaxId:1313] [110525] (1 PDB entry)
      Uniprot Q97PK6
    3. Species Staphylococcus aureus [TaxId:1280] [187794] (1 PDB entry)
  4. Deoxycytidine kinase [89657] (1 species)
  5. Deoxyguanosine kinase [69480] (1 species)
  6. Deoxynucleoside monophosphate kinase [52546] (1 species)
    contains insert 4-helical bundle subdomain, residues 35-145
  7. Deoxyribonucleoside kinase [69478] (1 species)
  8. Dephospho-CoA kinase [75187] (4 species)
    1. Species Escherichia coli [TaxId:562] [82394] (5 PDB entries)
    2. Species Haemophilus influenzae [TaxId:727] [75188] (1 PDB entry)
    3. Species Thermotoga maritima [TaxId:2336] [187766] (1 PDB entry)
    4. Species Thermus thermophilus [TaxId:274] [102344] (1 PDB entry)
      TT1252
  9. Guanylate kinase [52542] (5 species)
    1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52543] (6 PDB entries)
    2. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [189750] (1 PDB entry)
    3. Species Escherichia coli [TaxId:562] [102338] (6 PDB entries)
    4. Species Mouse (Mus musculus) [TaxId:10090] [82393] (1 PDB entry)
    5. Species Mycobacterium tuberculosis [TaxId:1773] [102339] (2 PDB entries)
      Rv1389
  10. Guanylate kinase-like domain of Cask [69474] (1 species)
  11. Guanylate kinase-like domain of Psd-95 [69476] (1 species)
  12. Guanylate kinase-like domain of the L-type calcium channel [110527] (2 species)
    1. Species Norway rat (Rattus norvegicus) [TaxId:10116] [110529] (5 PDB entries)
      Uniprot P54287 38-362
    2. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [110528] (5 PDB entries)
      Uniprot P54288 234-451
  13. Hypothetical protein YorR [142211] (1 species)
  14. Polynucleotide kinase, kinase domain [75191] (1 species)
  15. Probable kinase LmjF30.1890 [117528] (1 species)
  16. Thymidine kinase [52552] (4 species)
    contains insert all-alpha subdomain, res. 251-322
    1. Species Equine herpesvirus type 4 [TaxId:10331] [102340] (4 PDB entries)
    2. Species Herpes simplex virus type 1, different strains [TaxId:10298] [52553] (33 PDB entries)
      Uniprot P03176 46-375
    3. Species Herpes simplex virus type i [311159] (1 PDB entry)
    4. Species Varicella-Zoster virus [TaxId:10335] [89659] (1 PDB entry)
  17. Thymidylate kinase [52563] (5 species)
    1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52564] (3 PDB entries)
    2. Species Escherichia coli [TaxId:562] [52565] (2 PDB entries)
    3. Species Human (Homo sapiens) [TaxId:9606] [64010] (20 PDB entries)
    4. Species Mycobacterium tuberculosis [TaxId:1773] [69482] (9 PDB entries)
    5. Species Mycobacterium tuberculosis [TaxId:83332] [346929] (5 PDB entries)
  18. Transcriptional regulator NadR, ribosylnicotinamide kinase domain [75189] (1 species)
  19. UMP/CMP kinase [52550] (2 species)
    1. Species Human (Homo sapiens) [TaxId:9606] [110526] (1 PDB entry)
      Uniprot P30085
    2. Species Slime mold (Dictyostelium discoideum) [TaxId:44689] [52551] (6 PDB entries)
  20. Uridylate kinase [52544] (1 species)
  21. automated matches [190087] (15 species)
    not a true protein
    1. Species Bacillus subtilis [TaxId:1423] [189093] (1 PDB entry)
    2. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [311340] (1 PDB entry)
    3. Species Escherichia coli [TaxId:562] [187701] (2 PDB entries)
    4. Species Escherichia coli [TaxId:83333] [356329] (1 PDB entry)
    5. Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [233748] (6 PDB entries)
    6. Species Herpes simplex virus type i [311158] (1 PDB entry)
    7. Species Human (Homo sapiens) [TaxId:9606] [187523] (7 PDB entries)
    8. Species Methanococcus maripaludis [TaxId:39152] [189067] (1 PDB entry)
    9. Species Methanotorris igneus [TaxId:2189] [379246] (3 PDB entries)
    10. Species Mycobacterium tuberculosis [TaxId:1773] [186809] (11 PDB entries)
    11. Species Black rockcod (Notothenia coriiceps) [TaxId:8208] [353563] (3 PDB entries)
    12. Species Poecilia reticulata [TaxId:8081] [357578] (1 PDB entry)
    13. Species Vibrio cholerae [TaxId:243277] [225848] (2 PDB entries)
    14. Species Xiphophorus maculatus [TaxId:8083] [357570] (1 PDB entry)
    15. Species Yersinia pseudotuberculosis [TaxId:502800] [226541] (1 PDB entry)

More info for Family c.37.1.1: Nucleotide and nucleoside kinases

Timeline for Family c.37.1.1: Nucleotide and nucleoside kinases: