Lineage for Protein: Thioredoxin reductase

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2849308Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
    core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander
  4. 2849309Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (9 families) (S)
  5. 2849878Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (25 proteins)
    duplication: both domains have similar folds and functions
    most members of the family contain common C-terminal alpha+beta domain
  6. 2850173Protein Thioredoxin reductase [51950] (2 species)
    lacks the "interface" C-terminal alpha+beta domain

Species:

  1. 2850174Escherichia coli [TaxId:562] [51951] (5 PDB entries)
    1. Domains for 1cl0:
      1. 2850181Domain d1cl0a1: 1cl0 A:1-118,A:245-317 [30535]
        complexed with fad
        missing some secondary structures that made up less than one-third of the common domain
      2. 2850182Domain d1cl0a2: 1cl0 A:119-244 [30536]
        complexed with fad
        missing some secondary structures that made up less than one-third of the common domain
    2. Domains for 1f6m:
      1. 2850183Domain d1f6ma1: 1f6m A:1-118,A:245-320 [30537]
        Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
        complexed with thioredoxin
        protein/RNA complex; complexed with 3aa, fad
        missing some secondary structures that made up less than one-third of the common domain
      2. 2850184Domain d1f6ma2: 1f6m A:119-244 [30538]
        Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
        complexed with thioredoxin
        protein/RNA complex; complexed with 3aa, fad
        missing some secondary structures that made up less than one-third of the common domain
      3. 2850185Domain d1f6mb1: 1f6m B:1-118,B:245-320 [30539]
        Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
        complexed with thioredoxin
        protein/RNA complex; complexed with 3aa, fad
        missing some secondary structures that made up less than one-third of the common domain
      4. 2850186Domain d1f6mb2: 1f6m B:119-244 [30540]
        Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
        complexed with thioredoxin
        protein/RNA complex; complexed with 3aa, fad
        missing some secondary structures that made up less than one-third of the common domain
      5. 2850187Domain d1f6me1: 1f6m E:1-118,E:245-320 [30541]
        Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
        complexed with thioredoxin
        protein/RNA complex; complexed with 3aa, fad
        missing some secondary structures that made up less than one-third of the common domain
      6. 2850188Domain d1f6me2: 1f6m E:119-244 [30542]
        Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
        complexed with thioredoxin
        protein/RNA complex; complexed with 3aa, fad
        missing some secondary structures that made up less than one-third of the common domain
      7. 2850189Domain d1f6mf1: 1f6m F:1-118,F:245-320 [30543]
        Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
        complexed with thioredoxin
        protein/RNA complex; complexed with 3aa, fad
        missing some secondary structures that made up less than one-third of the common domain
      8. 2850190Domain d1f6mf2: 1f6m F:119-244 [30544]
        Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
        complexed with thioredoxin
        protein/RNA complex; complexed with 3aa, fad
        missing some secondary structures that made up less than one-third of the common domain
    3. Domains for 1tde:
      1. 2850177Domain d1tdea1: 1tde A:1-118,A:245-316 [30531]
        complexed with fad
        missing some secondary structures that made up less than one-third of the common domain
      2. 2850178Domain d1tdea2: 1tde A:119-244 [30532]
        complexed with fad
        missing some secondary structures that made up less than one-third of the common domain
    4. Domains for 1tdf:
      1. 2850179Domain d1tdfa1: 1tdf A:1-118,A:245-316 [30533]
        complexed with fad, nap
        missing some secondary structures that made up less than one-third of the common domain
      2. 2850180Domain d1tdfa2: 1tdf A:119-244 [30534]
        complexed with fad, nap
        missing some secondary structures that made up less than one-third of the common domain
    5. Domains for 1trb:
      1. 2850175Domain d1trba1: 1trb A:1-118,A:245-316 [30529]
        complexed with fad
        missing some secondary structures that made up less than one-third of the common domain
      2. 2850176Domain d1trba2: 1trb A:119-244 [30530]
        complexed with fad
        missing some secondary structures that made up less than one-third of the common domain
  2. 2850191Thale cress (Arabidopsis thaliana) [TaxId:3702] [51952] (1 PDB entry)
    • Domains for 1vdc:
      1. 2850192Domain d1vdca1: 1vdc A:1-117,A:244-316 [30545]
        complexed with fad, so4
        missing some secondary structures that made up less than one-third of the common domain
      2. 2850193Domain d1vdca2: 1vdc A:118-243 [30546]
        complexed with fad, so4
        missing some secondary structures that made up less than one-third of the common domain

More info for Protein Thioredoxin reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains

Timeline for Protein Thioredoxin reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains: