SCOPe 2.05: Protein: Trp synthase alpha-subunit

Lineage for Protein: Trp synthase alpha-subunit

Root: SCOPe 2.05
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
the first seven superfamilies have similar phosphate-binding sites

Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (7 families)
Family c.1.2.4: Tryptophan biosynthesis enzymes [51381] (4 proteins)
Protein Trp synthase alpha-subunit [51388] (8 species)

Species:

Escherichia coli [TaxId:562] [117360] (3 PDB entries)
Uniprot P00928
1. Domain for 1v7y:
  - Domain d1v7ya1: 1v7y A:1-268 [119865]
    Other proteins in same PDB: d1v7yb_
    complexed with so4
2. Domains for 1xc4:
  1. Domain d1xc4a_: 1xc4 A: [115104]
    complexed with gol, so4
  2. Domain d1xc4b_: 1xc4 B: [115105]
    complexed with gol, so4
3. Domains for 1xcf:
  1. Domain d1xcfa_: 1xcf A: [115118]
  2. Domain d1xcfb_: 1xcf B: [115119]
Maize (Zea mays) [TaxId:4577] [117361] (2 PDB entries)
Uniprot P42390
1. Domains for 1rd5:
  1. Domain d1rd5a_: 1rd5 A: [111772]
    complexed with mla
  2. Domain d1rd5b_: 1rd5 B: [111773]
    complexed with mla
2. Domain for 1tjr:
  - Domain d1tjra1: 1tjr A:86-346 [119292]
    Other proteins in same PDB: d1tjrb_
    complexed with so4
Pyrococcus furiosus [TaxId:186497] [279285] (1 PDB entry)
- Domains for 5e0k:
  1. Domain d5e0ka_: 5e0k A: [279286]
    Other proteins in same PDB: d5e0kb_, d5e0kd_, d5e0kf_, d5e0kh_, d5e0kj_, d5e0kl_
    automated match to d1geqa_
    complexed with po4
  2. Domain d5e0kc_: 5e0k C: [279288]
    Other proteins in same PDB: d5e0kb_, d5e0kd_, d5e0kf_, d5e0kh_, d5e0kj_, d5e0kl_
    automated match to d1geqa_
    complexed with po4
  3. Domain d5e0ke_: 5e0k E: [279295]
    Other proteins in same PDB: d5e0kb_, d5e0kd_, d5e0kf_, d5e0kh_, d5e0kj_, d5e0kl_
    automated match to d1geqa_
    complexed with po4
  4. Domain d5e0kg_: 5e0k G: [279289]
    Other proteins in same PDB: d5e0kb_, d5e0kd_, d5e0kf_, d5e0kh_, d5e0kj_, d5e0kl_
    automated match to d1geqa_
    complexed with po4
  5. Domain d5e0ki_: 5e0k I: [279293]
    Other proteins in same PDB: d5e0kb_, d5e0kd_, d5e0kf_, d5e0kh_, d5e0kj_, d5e0kl_
    automated match to d1geqa_
    complexed with po4
  6. Domain d5e0kk_: 5e0k K: [279294]
    Other proteins in same PDB: d5e0kb_, d5e0kd_, d5e0kf_, d5e0kh_, d5e0kj_, d5e0kl_
    automated match to d1geqa_
    complexed with po4
Pyrococcus furiosus [TaxId:2261] [51390] (10 PDB entries)
1. Domains for 1geq:
  1. Domain d1geqa_: 1geq A: [28589]
    CASP4
  2. Domain d1geqb_: 1geq B: [28590]
    CASP4
2. Domains for 1wdw:
  1. Domain d1wdwa_: 1wdw A: [120916]
    Other proteins in same PDB: d1wdwb_, d1wdwd_, d1wdwf_, d1wdwh_, d1wdwj_, d1wdwl_
    automated match to d1geqa_
    complexed with plp
  2. Domain d1wdwc_: 1wdw C: [120918]
    Other proteins in same PDB: d1wdwb_, d1wdwd_, d1wdwf_, d1wdwh_, d1wdwj_, d1wdwl_
    automated match to d1geqa_
    complexed with plp
  3. Domain d1wdwe_: 1wdw E: [120920]
    Other proteins in same PDB: d1wdwb_, d1wdwd_, d1wdwf_, d1wdwh_, d1wdwj_, d1wdwl_
    automated match to d1geqa_
    complexed with plp
  4. Domain d1wdwg_: 1wdw G: [120922]
    Other proteins in same PDB: d1wdwb_, d1wdwd_, d1wdwf_, d1wdwh_, d1wdwj_, d1wdwl_
    automated match to d1geqa_
    complexed with plp
  5. Domain d1wdwi_: 1wdw I: [120924]
    Other proteins in same PDB: d1wdwb_, d1wdwd_, d1wdwf_, d1wdwh_, d1wdwj_, d1wdwl_
    automated match to d1geqa_
    complexed with plp
  6. Domain d1wdwk_: 1wdw K: [120926]
    Other proteins in same PDB: d1wdwb_, d1wdwd_, d1wdwf_, d1wdwh_, d1wdwj_, d1wdwl_
    automated match to d1geqa_
    complexed with plp
3. Domains for 2dzp:
  1. Domain d2dzpa_: 2dzp A: [163755]
    automated match to d1geqa_
    mutant
  2. Domain d2dzpb_: 2dzp B: [163756]
    automated match to d1geqa_
    mutant
4. Domains for 2dzs:
  1. Domain d2dzsa_: 2dzs A: [163757]
    automated match to d1geqa_
    mutant
  2. Domain d2dzsb_: 2dzs B: [163758]
    automated match to d1geqa_
    mutant
5. Domains for 2dzt:
  1. Domain d2dzta_: 2dzt A: [163759]
    automated match to d1geqa_
    mutant
  2. Domain d2dztb_: 2dzt B: [163760]
    automated match to d1geqa_
    mutant
6. Domains for 2dzu:
  1. Domain d2dzua_: 2dzu A: [163761]
    automated match to d1geqa_
    mutant
  2. Domain d2dzub_: 2dzu B: [163762]
    automated match to d1geqa_
    mutant
7. Domains for 2dzv:
  1. Domain d2dzva_: 2dzv A: [163763]
    automated match to d1geqa_
    mutant
  2. Domain d2dzvb_: 2dzv B: [163764]
    automated match to d1geqa_
    mutant
8. Domains for 2dzw:
  1. Domain d2dzwa_: 2dzw A: [163765]
    automated match to d1geqa_
    mutant
  2. Domain d2dzwb_: 2dzw B: [163766]
    automated match to d1geqa_
    mutant
9. Domains for 2dzx:
  1. Domain d2dzxa_: 2dzx A: [163767]
    automated match to d1geqa_
    mutant
  2. Domain d2dzxb_: 2dzx B: [163768]
    automated match to d1geqa_
    mutant
10. Domains for 2e09:
  1. Domain d2e09a_: 2e09 A: [163779]
    automated match to d1geqa_
    mutant
  2. Domain d2e09b_: 2e09 B: [163780]
    automated match to d1geqa_
    mutant
Salmonella enterica [TaxId:90371] [229811] (5 PDB entries)
1. Domain for 4hn4:
  - Domain d4hn4a_: 4hn4 A: [230037]
    Other proteins in same PDB: d4hn4b_
    automated match to d1k8ya_
    complexed with 0jo, bcn, cs, f9f, peg
2. Domain for 4hpj:
  - Domain d4hpja_: 4hpj A: [230039]
    Other proteins in same PDB: d4hpjb_
    automated match to d1k8ya_
    complexed with 1d0, bcn, cl, cs, f9f, peg
3. Domain for 4hpx:
  - Domain d4hpxa_: 4hpx A: [229812]
    Other proteins in same PDB: d4hpxb_
    automated match to d1k8ya_
    complexed with 0jo, bcn, bzi, cs, f9f, peg
4. Domain for 4ht3:
  - Domain d4ht3a_: 4ht3 A: [230250]
    Other proteins in same PDB: d4ht3b_
    automated match to d1k8ya_
    complexed with bcn, cl, cs, edo, f9f, peg, pg5, pge, plp
5. Domain for 4kkx:
  - Domain d4kkxa_: 4kkx A: [230258]
    Other proteins in same PDB: d4kkxb_
    automated match to d1k8ya_
    complexed with aq3, edo, f6f, na, peg, pge
Salmonella typhimurium [TaxId:90371] [51389] (41 PDB entries)
1. Domain for 1a50:
  - Domain d1a50a_: 1a50 A: [28580]
    Other proteins in same PDB: d1a50b_
    complexed with fip, na, plp
2. Domain for 1a5a:
  - Domain d1a5aa_: 1a5a A: [28576]
    Other proteins in same PDB: d1a5ab_
    complexed with k, plp; mutant
3. Domain for 1a5b:
  - Domain d1a5ba_: 1a5b A: [28575]
    Other proteins in same PDB: d1a5bb_
    complexed with igp, k, plp; mutant
4. Domain for 1a5s:
  - Domain d1a5sa_: 1a5s A: [28581]
    Other proteins in same PDB: d1a5sb_
    complexed with fip, na, plp, ser
5. Domain for 1beu:
  - Domain d1beua_: 1beu A: [28574]
    Other proteins in same PDB: d1beub_
    complexed with ipl, k, pls
6. Domain for 1bks:
  - Domain d1bksa_: 1bks A: [28585]
    Other proteins in same PDB: d1bksb_
    complexed with na, plp
7. Domain for 1c29:
  - Domain d1c29a_: 1c29 A: [28587]
    Other proteins in same PDB: d1c29b_
    complexed with he1, na, plp
8. Domain for 1c8v:
  - Domain d1c8va_: 1c8v A: [28582]
    Other proteins in same PDB: d1c8vb_
    complexed with he1, na, plp
9. Domain for 1c9d:
  - Domain d1c9da_: 1c9d A: [28586]
    Other proteins in same PDB: d1c9db_
    complexed with hf1, na, plp
10. Domain for 1cw2:
  - Domain d1cw2a_: 1cw2 A: [28578]
    Other proteins in same PDB: d1cw2b_
    complexed with hsp, na, plp
11. Domain for 1cx9:
  - Domain d1cx9a_: 1cx9 A: [28584]
    Other proteins in same PDB: d1cx9b_
    complexed with na, nhp, plp
12. Domain for 1fuy:
  - Domain d1fuya_: 1fuy A: [28579]
    Other proteins in same PDB: d1fuyb_
    complexed with fip, na, plp; mutant
13. Domain for 1k3u:
  - Domain d1k3ua_: 1k3u A: [72030]
    Other proteins in same PDB: d1k3ub_
    complexed with iad, na, plp
14. Domain for 1k7e:
  - Domain d1k7ea_: 1k7e A: [72097]
    Other proteins in same PDB: d1k7eb_
    complexed with iag, na, plp
15. Domain for 1k7f:
  - Domain d1k7fa_: 1k7f A: [72099]
    Other proteins in same PDB: d1k7fb_
    complexed with iav, plp
16. Domain for 1k7x:
  - Domain d1k7xa_: 1k7x A: [72134]
    Other proteins in same PDB: d1k7xb_
    complexed with na, plp; mutant
17. Domain for 1k8x:
  - Domain d1k8xa_: 1k8x A: [77288]
    Other proteins in same PDB: d1k8xb_
    complexed with na, plp; mutant
18. Domain for 1k8y:
  - Domain d1k8ya_: 1k8y A: [72183]
    Other proteins in same PDB: d1k8yb_
    complexed with 13p, na, plp; mutant
19. Domain for 1k8z:
  - Domain d1k8za_: 1k8z A: [72185]
    Other proteins in same PDB: d1k8zb_
    complexed with iag, na, plp; mutant
20. Domain for 1kfb:
  - Domain d1kfba_: 1kfb A: [77369]
    Other proteins in same PDB: d1kfbb_
    complexed with igp, plp; mutant
21. Domain for 1kfc:
  - Domain d1kfca_: 1kfc A: [77371]
    Other proteins in same PDB: d1kfcb_
    complexed with ipl, na, plp; mutant
22. Domain for 1kfe:
  - Domain d1kfea_: 1kfe A: [77373]
    Other proteins in same PDB: d1kfeb_
    complexed with na, pls; mutant
23. Domain for 1kfj:
  - Domain d1kfja_: 1kfj A: [90958]
    Other proteins in same PDB: d1kfjb_
    complexed with na, pls
24. Domain for 1kfk:
  - Domain d1kfka_: 1kfk A: [90960]
    Other proteins in same PDB: d1kfkb_
    complexed with na, plp
25. Domain for 1qop:
  - Domain d1qopa_: 1qop A: [28570]
    Other proteins in same PDB: d1qopb_
    complexed with ipl, na, plp
26. Domain for 1qoq:
  - Domain d1qoqa_: 1qoq A: [28571]
    Other proteins in same PDB: d1qoqb_
    complexed with igp, plp
27. Domain for 1tjp:
  - Domain d1tjpa_: 1tjp A: [119290]
    Other proteins in same PDB: d1tjpb_
    automated match to d1a5aa_
    complexed with hpf, na, plp
28. Domain for 1ttp:
  - Domain d1ttpa_: 1ttp A: [28569]
    Other proteins in same PDB: d1ttpb_
    complexed with cs, plp
29. Domain for 1ttq:
  - Domain d1ttqa_: 1ttq A: [28568]
    Other proteins in same PDB: d1ttqb_
    complexed with k, plp
30. Domain for 1ubs:
  - Domain d1ubsa_: 1ubs A: [28573]
    Other proteins in same PDB: d1ubsb_
    complexed with na, plp, ser; mutant
31. Domain for 2cle:
  - Domain d2clea1: 2cle A:2-267 [130572]
    Other proteins in same PDB: d2cleb1
    automatically matched to d1k3ua_
    complexed with f6f, na, plp
32. Domain for 2clh:
  - Domain d2clha1: 2clh A:1-267 [130574]
    Other proteins in same PDB: d2clhb1
    automatically matched to d1k3ua_
    complexed with f19, na, plp
33. Domain for 2rh9:
  - Domain d2rh9a_: 2rh9 A: [152034]
    Other proteins in same PDB: d2rh9b_
    automated match to d1a5aa_
    complexed with igp, na, plp
34. Domain for 2rhg:
  - Domain d2rhga_: 2rhg A: [152050]
    Other proteins in same PDB: d2rhgb_
    automated match to d1a5aa_
    complexed with igp, na, plp
35. Domain for 2trs:
  - Domain d2trsa_: 2trs A: [28577]
    Other proteins in same PDB: d2trsb_
    complexed with ipl, na, pls; mutant
36. Domain for 2tsy:
  - Domain d2tsya_: 2tsy A: [28583]
    Other proteins in same PDB: d2tsyb_
    complexed with g3p, na, pls; mutant
37. Domain for 2tys:
  - Domain d2tysa_: 2tys A: [28572]
    Other proteins in same PDB: d2tysb_
    complexed with na, plt; mutant
38. Domain for 2wsy:
  - Domain d2wsya_: 2wsy A: [28588]
    Other proteins in same PDB: d2wsyb_
    complexed with na, plp
39. Domain for 3cep:
  - Domain d3cepa_: 3cep A: [156532]
    Other proteins in same PDB: d3cepb_
    automated match to d1k3ua_
    complexed with cs, g3p, plp
40. Domain for 3pr2:
  - Domain d3pr2a_: 3pr2 A: [183929]
    Other proteins in same PDB: d3pr2b_
    automated match to d1a50a_
    complexed with 7mn, cs, f9f
41. Domain for 4wx2:
  - Domain d4wx2a_: 4wx2 A: [279501]
    Other proteins in same PDB: d4wx2b_
    automated match to d1k8ya_
    complexed with edo, f6f, na, peg, plp
Shewanella frigidimarina [TaxId:56812] [224873] (1 PDB entry)
- Domains for 3vnd:
  1. Domain d3vnda_: 3vnd A: [194115]
    automated match to d3nava_
    complexed with pe8, so4
  2. Domain d3vndb_: 3vnd B: [194123]
    automated match to d3nava_
    complexed with pe8, so4
  3. Domain d3vndc_: 3vnd C: [194117]
    automated match to d3nava_
    complexed with pe8, so4
  4. Domain d3vndd_: 3vnd D: [194119]
    automated match to d3nava_
    complexed with pe8, so4
  5. Domain d3vnde_: 3vnd E: [194118]
    automated match to d3nava_
    complexed with pe8, so4
  6. Domain d3vndf_: 3vnd F: [194120]
    automated match to d3nava_
    complexed with pe8, so4
  7. Domain d3vndg_: 3vnd G: [194116]
    automated match to d3nava_
    complexed with pe8, so4
  8. Domain d3vndh_: 3vnd H: [194122]
    automated match to d3nava_
    complexed with pe8, so4
Thermus thermophilus [TaxId:274] [102038] (1 PDB entry)
- Domain for 1ujp:
  - Domain d1ujpa_: 1ujp A: [99462]
    complexed with cit

More info for Protein Trp synthase alpha-subunit from c.1.2.4: Tryptophan biosynthesis enzymes

Timeline for Protein Trp synthase alpha-subunit from c.1.2.4: Tryptophan biosynthesis enzymes:

Protein Trp synthase alpha-subunit from c.1.2.4: Tryptophan biosynthesis enzymes first appeared (with stable ids) in SCOP 1.55
Protein Trp synthase alpha-subunit from c.1.2.4: Tryptophan biosynthesis enzymes appears in SCOPe 2.04
Protein Trp synthase alpha-subunit from c.1.2.4: Tryptophan biosynthesis enzymes appears in SCOPe 2.06
Protein Trp synthase alpha-subunit from c.1.2.4: Tryptophan biosynthesis enzymes appears in the current release, SCOPe 2.08