SCOPe 2.05: Family c.1.2.4: Tryptophan biosynthesis enzymes

Lineage for Family c.1.2.4: Tryptophan biosynthesis enzymes

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (7 families)

5. Family c.1.2.4: Tryptophan biosynthesis enzymes [51381] (4 proteins)

Proteins:

1. Indole-3-glycerophosphate synthase, IPGS [51385] (4 species)

   1. Species Escherichia coli [TaxId:562] [51386] (2 PDB entries)
      merged in bifunctional enzyme with PRA isomerase

   2. Species Sulfolobus solfataricus [TaxId:2287] [51387] (6 PDB entries)

   3. Species Thermotoga maritima [TaxId:2336] [75052] (2 PDB entries)
      TM0140

   4. Species Thermus thermophilus [TaxId:274] [102037] (1 PDB entry)

2. N-(5'phosphoribosyl)antranilate isomerase, PRAI [51382] (3 species)

   1. Species Escherichia coli [TaxId:562] [51383] (1 PDB entry)
      merged in bifunctional enzyme with IPG synthase

   2. Species Thermotoga maritima [TaxId:2336] [51384] (3 PDB entries)

   3. Species Thermus thermophilus [TaxId:274] [102036] (1 PDB entry)

3. Trp synthase alpha-subunit [51388] (8 species)

   1. Species Escherichia coli [TaxId:562] [117360] (3 PDB entries)
      Uniprot P00928

   2. Species Maize (Zea mays) [TaxId:4577] [117361] (2 PDB entries)
      Uniprot P42390

   3. Species Pyrococcus furiosus [TaxId:186497] [279285] (1 PDB entry)

   4. Species Pyrococcus furiosus [TaxId:2261] [51390] (10 PDB entries)

   5. Species Salmonella enterica [TaxId:90371] [229811] (5 PDB entries)

   6. Species Salmonella typhimurium [TaxId:90371] [51389] (41 PDB entries)

   7. Species Shewanella frigidimarina [TaxId:56812] [224873] (1 PDB entry)

   8. Species Thermus thermophilus [TaxId:274] [102038] (1 PDB entry)

4. automated matches [190053] (8 species)
   not a true protein

   1. Species Artificial gene [TaxId:32630] [188991] (7 PDB entries)

   2. Species Escherichia coli [TaxId:562] [186794] (2 PDB entries)

   3. Species Maize (Zea mays) [TaxId:4577] [186774] (1 PDB entry)

   4. Species Salmonella typhimurium [TaxId:90371] [189632] (10 PDB entries)

   5. Species Sulfolobus solfataricus [TaxId:2287] [190005] (7 PDB entries)

   6. Species Sulfolobus solfataricus [TaxId:273057] [196207] (2 PDB entries)

   7. Species Thermus thermophilus HB8 [TaxId:300852] [186840] (1 PDB entry)

   8. Species Vibrio cholerae [TaxId:243277] [189383] (1 PDB entry)

More info for Family c.1.2.4: Tryptophan biosynthesis enzymes

Timeline for Family c.1.2.4: Tryptophan biosynthesis enzymes:

• Family c.1.2.4: Tryptophan biosynthesis enzymes first appeared (with stable ids) in SCOP 1.55
  
• Family c.1.2.4: Tryptophan biosynthesis enzymes appears in SCOPe 2.04
  
• Family c.1.2.4: Tryptophan biosynthesis enzymes appears in SCOPe 2.06
  
• Family c.1.2.4: Tryptophan biosynthesis enzymes appears in the current release, SCOPe 2.08