SCOPe 2.05: Domain d2clha1: 2clh A:1-267

Lineage for d2clha1 (2clh A:1-267)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (7 families)

5. Family c.1.2.4: Tryptophan biosynthesis enzymes [51381] (4 proteins)

6. Protein Trp synthase alpha-subunit [51388] (8 species)

7. Species Salmonella typhimurium [TaxId:90371] [51389] (41 PDB entries)

8. Domain d2clha1: 2clh A:1-267 [130574]
   Other proteins in same PDB: d2clhb1
   automatically matched to d1k3ua_
   complexed with f19, na, plp

Details for d2clha1

PDB Entry: 2clh, 1.7 Å

PDB Description: tryptophan synthase in complex with (naphthalene-2'-sulfonyl)-2-amino- 1-ethylphosphate (f19)

PDB Compounds: (A:) tryptophan synthase alpha chain

SCOPe Domain Sequences for d2clha1:

Sequence, based on SEQRES records:

>d2clha1 c.1.2.4 (A:1-267) Trp synthase alpha-subunit {Salmonella typhimurium [TaxId: 90371]}
meryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdplad
gptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceq
vgvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsrs
gvtgaenrgalplhhlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivki
ieknlaspkqmlaelrsfvsamkaasr

Sequence, based on observed residues (ATOM records):

>d2clha1 c.1.2.4 (A:1-267) Trp synthase alpha-subunit {Salmonella typhimurium [TaxId: 90371]}
meryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdplad
gptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceq
vgvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsrs
gvtghhlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivkiieknlaspk
qmlaelrsfvsamkaasr

Timeline for d2clha1:

• d2clha1 first appeared in SCOP 1.73
  
• d2clha1 appears in SCOPe 2.04
  
• d2clha1 appears in SCOPe 2.06
  
• d2clha1 appears in the current release, SCOPe 2.08